2011年3月
Impaired ability to organize information in individuals with autism spectrum disorders and their siblings
NEUROSCIENCE RESEARCH
- ,
- ,
- ,
- ,
- 巻
- 69
- 号
- 3
- 開始ページ
- 252
- 終了ページ
- 257
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.neures.2010.11.007
- 出版者・発行元
- ELSEVIER IRELAND LTD
Despite rigorous research on disturbances of executive function and social cognition in autism spectrum disorders (ASD), little information has been available concerning higher cognitive functions, such as the ability to focus and associate relevant features to form categories, or 'organizing of information'. The purpose of this study was to investigate this issue by using the Wisconsin Card Sorting Test (WCST) and the Verbal Learning Task (VLT). Cognitive assessments were conducted in 22 individuals with ASD, 14 non-affected siblings, and 15 age-matched control subjects. Overall, individuals with ASD performed significantly worse on the WCST and VLT compared to their siblings and normal control subjects. Although siblings performed generally well on both tasks, they exhibited similar degree of perseverative responses in the WCST compared to the probands. A linear increase of the memory organization score in the VLT was also absent in siblings as well as the ASD group. These results suggest an impaired ability to organize information is one of the cognitive endophenotypes for ASD. (C) 2010 Elsevier Ireland Ltd and the japan Neuroscience Society. All rights reserved.
- リンク情報
-
- DOI
- https://doi.org/10.1016/j.neures.2010.11.007
- CiNii Articles
- http://ci.nii.ac.jp/naid/80021558360
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/21129422
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000287794600010&DestApp=WOS_CPL
- ID情報
-
- DOI : 10.1016/j.neures.2010.11.007
- ISSN : 0168-0102
- eISSN : 1872-8111
- CiNii Articles ID : 80021558360
- PubMed ID : 21129422
- Web of Science ID : WOS:000287794600010