SEIJU KOBAYASHI

Profile Information

Affiliation: -
: 院長, 心優会中江病院

Degree: 医学博士(札幌医科大学)

J-GLOBAL ID: 201901014888522740
researchmap Member ID: B000379185

老年精神医学、とくに認知症を専門にしております。日本老年精神医学会の専門医・指導医・評議員であります。

Research Interests

Research Areas

Life sciences / Psychiatry / 老年精神医学、認知症

Research History

Apr, 2017 - Present

Sapporo Medical University
Jun, 2013 - Mar, 2017

Sapporo Medical University
Oct, 2012 - May, 2013

Sapporo Medical University
Apr, 2012 - Sep, 2012

Sapporo Medical University
Apr, 2010 - Mar, 2012

Sapporo Medical University
Apr, 2008 - Mar, 2010

Hospital, Sapporo Medical University
Apr, 2004 - Mar, 2008

診療医, 精神神経科, 砂川市立病院
Apr, 2003 - Mar, 2004

Hospital, Sapporo Medical University
Apr, 2002 - Mar, 2003

臨床研修医, 精神科, 五稜会病院
Apr, 2001 - Mar, 2002

Hospital, Sapporo Medical University

Education

Apr, 1995 - Mar, 2001

School of Medicine, Sapporo Medical University
Apr, 1991 - Mar, 1994

北海道立札幌南高等学校

Committee Memberships

Awards

Papers

Current research of idiopathic normal pressure hydrocephalus: Pathogenesis, diagnosis and treatment

Tetsuro Ishida, Tomonori Murayama, Seiju Kobayashi

World Journal of Clinical Cases, 11(16) 3706-3713, Jun 6, 2023
A case report of an alcoholic with delirium tremens diagnosed with hypopharyngeal cancer: Psychiatrists played important roles in the smooth diagnosis and treatments

Tetsuro Ishida, Tomonori Murayama, Seiju Kobayashi

Psychiatry and Clinical Neurosciences Reports, 1(4), Dec, 2022
A case report of nonsurgical idiopathic normal pressure hydrocephalus differentiated from Alzheimer's dementia: Levetiracetam was effective in symptomatic epilepsy

Tetsuro Ishida, Tomonori Murayama, Seiju Kobayashi

Psychiatry and Clinical Neurosciences Reports, 1(3), Sep, 2022
Pneumonia and seizures due to hypereosinophilic syndrome-organ damage and eosinophilia without synchronisation: A case report.

Tetsuro Ishida, Tomonori Murayama, Seiju Kobayashi

World journal of clinical cases, 10(18) 6325-6332, Jun 26, 2022
Effectiveness of electroconvulsive therapy in patients with advanced Parkinson’s disease.

Tomonori Murayama, Seiju Kobayashi, Takeshi Matsuoka, Yoshiyasu Kigawa, Tomotaka Ishida, Kengo Hyakumachi, Kumiko Utsumi, Chiaki Kawanishi

The Journal of ECT, Oct, 2020 Peer-reviewed
Longitudinal observation of ten family members with idiopathic basal ganglia calcification: A case report.

Kobayashi S, Utsumi K, Tateno M, Iwamoto T, Murayama T, Sohma H, Ukai W, Hashimoto E, Kawanishi C

World journal of clinical cases, 7(12) 1483-1491, Jun, 2019 Peer-reviewed
Effect of Memantine on Brain Metabolic Activity and Perfusion in Drug-naïve Moderate Alzheimer’s Disease Patients.

Iwamoto T, Utsumi K, Kobayashi S, Yasumura S, Hatakeyama S, Hayashi A, Kawanishi C

Neuropsychiatry, 8(2) 546-554, 2018 Peer-reviewed
The usefulness of combined brain perfusion single-photon emission computed tomography, Dopamine-transporter single-photon emission computed tomography, and I-123-metaiodobenzylguanidine myocardial scintigraphy for the diagnosis of dementia with Lewy bodies

Seiju Kobayashi, Kanae Makino, Shigeki Hatakeyama, Takao Ishii, Masaru Tateno, Tomo Iwamoto, Hanako Tsujino, Kazuhito Kawasaki, Kouhei Mikuni, Wataru Ukai …

PSYCHOGERIATRICS, 17(4) 247-255, Jul, 2017 Peer-reviewed
統合失調症に若年性アルツハイマー型認知症の合併が疑われた一例その診断と治療経過について

松山清治, 出利葉健太, 小林清樹, 岩本倫, 牧野愛恵, 村山友規, 石田哲朗, 畠山茂樹, 相馬仁, 河西千秋

老年精神医学雑誌, 28(増刊II) 208-208, Jun, 2017
認知症の行動・心理症状と性差の関係

小林清樹, 牧野愛恵, 岩本倫, 松山清治, 中野倫仁, 内海久美子

精神神経学雑誌, (2017特別号) S506-S506, Jun, 2017 Peer-reviewed
加齢に伴い統合失調症患者にアルツハイマー型認知症の合併が疑われた一例

小林清樹, 出利葉健太, 松山清治, 河西千秋

日本抗加齢医学会総会プログラム・抄録集, 16回 237-237, Jun, 2016 Peer-reviewed
Pathological analysis of refractory depression using fetal alcohol and adolescent corticosterone double stress model

Kengo Furuse, Hanako Tsujino, Yoshiyasu Kigawa, Masaya Tayama, Wataru Ukai, Takao Ishii, Tomo Iwamoto, Masaki Shiraishi, Seiju Kobayashi, Eri Hashimoto …

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 19 119-120, Jun, 2016 Peer-reviewed
The effect of APOE ϵ4 allele on brain perfusion SPECT in late onset Alzheimer's disease by an automated program, 3DSRT

Seiju Kobayashi, Takao Ishii, Masaru Tateno, Hitoshi Sohma, Yasuo Kokai, Yoichi M. Ito, Tomo Iwamoto, Kengo Furuse, Hanako Tsujino, Hidetoshi Morii …

Neuropsychiatry, 6(2) 55-63, 2016 Peer-reviewed
統合失調症と若年性アルツハイマー型認知症の合併が疑われた一例

出利葉健太, 松山清治, 小林清樹, 石井貴男, 橋本恵理, 河西千秋

精神神経学雑誌, (2015特別) S563-S563, Jun, 2015 Peer-reviewed
Evaluation of SLC20A2 mutations that cause idiopathic basal ganglia calcification in Japan

Megumi Yamada, Masaki Tanaka, Mari Takagi, Seiju Kobayashi, Yoshiharu Taguchi, Shutaro Takashima, Kortaro Tanaka, Tetsuo Touge, Hiroyuki Hatsuta, Shigeo Murayama …

NEUROLOGY, 82(8) 705-712, Feb, 2014 Peer-reviewed
依存研究を基盤にした精神疾患の病因解明の試み精神疾患に対する再生医療的アプローチの可能性

鵜飼渉, 橋本恵理, 石井貴男, 木川昌康, 古瀬健吾, 辻野華子, 白坂知彦, 吉永敏弘, 小林清樹, 齋藤利和

日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集, 23回・43回 130-130, Oct, 2013
Effects of atelocollagen on neural stem cell function and its migrating capacity into brain in psychiatric disease model

Toshihiro Yoshinaga, Eri Hashimoto, Wataru Ukai, Takao Ishii, Tomohiro Shirasaka, Yoshiyasu Kigawa, Masaru Tateno, Hiroo Kaneta, Kimihiko Watanabe, Takeshi Igarashi …

JOURNAL OF NEURAL TRANSMISSION, 120(10) 1491-1498, Oct, 2013 Peer-reviewed
北海道におけるat risk mental state患者の受診経路に関する多施設調査

大久保亮, 橋本直樹, 伊藤かほり, 大宮友貴, 中右麻理子, 馬場俊明, 白坂知彦, 小林清樹, 立花蘭, 館農勝 …

精神神経学雑誌, (2012特別) S-412, May, 2012
Apolipoprotein E4 Frequencies in a Japanese Population with Alzheimer's Disease and Dementia with Lewy Bodies

Seiju Kobayashi, Masaru Tateno, Tae Woo Park, Kumiko Utsumi, Hitoshi Sohma, Yoichi M. Ito, Yasuo Kokai, Toshikazu Saito

PLOS ONE, 6(4) e18569, Apr, 2011 Peer-reviewed
若手はいかにしてサブスペシャリティに興味をもつのか

内田直樹, 上原久美, 小田陽彦, 川田良作, 菊地紗耶, 小林清樹, 柴田敬祐, 白坂知彦, 鈴木宗幸, 館農勝 …

九州神経精神医学, 56(3-4) 179-179, Dec, 2010

Misc.

家族性特発性基底核石灰化症の1家系の検討

小林清樹, 齋藤正樹, 山内理香, 岩本倫, 牧野愛恵, 松山清治, 畠山茂樹, 村山友規, 石田哲朗, 渡邊公彦 …

老年精神医学雑誌, 28(増刊II) 169-169, Jun, 2017
認知症の行動・心理症状と性差の関係

小林清樹, 牧野愛恵, 岩本倫, 松山清治, 中野倫仁, 内海久美子

精神神経学雑誌, (2017特別号) S506-S506, Jun, 2017
A Structure of Cognitive Disturbance, BPSD, and Disability of Daily Life in the Vascular Dementia

58(11) 953-958, Nov, 2016
Electroconvulsive Therapy in Advanced Parkinson Disease Patients with Psychosis

58(8) 677-684, Aug, 2016
統合失調症にアルツハイマー型認知症を合併した1例

DERIBA KENTA, MATSUYAMA KIYOJI, KOBAYASHI SEIJU, FURUSE KENGO, ISHII TAKAO, HASHIMOTO ERI

精神神経学雑誌, 116(12) 1039-1040, Dec 25, 2014
本邦における特発性大脳基底核石灰化症の臨床的・遺伝学的検討

山田恵, 田中真生, 高木麻里, 小林清樹, 田口芳治, 高嶋修太郎, 田中耕太郎, 峠哲男, 初田裕幸, 村山繁雄 …

臨床神経学, 54(Suppl.) S66-S66, Dec, 2014
レヴィー小体型認知症に対するECTの有効性

早坂郁, 松山清治, 坂田太, 白石将毅, 荻原英之, 小林清樹, 石井貴男, 橋本恵理

精神神経学雑誌, 116(12) 1039-1039, Dec, 2014
Apolipoprotein E4 frequencies in a Japanese population with Alzheimer's disease and dementia with Lewy bodies

Seiju Kobayashi, M. Tateno, T. Saito, H. Sohma, Y. Kokai, T. Park, K. Utsumi, Y. Ito

INTERNATIONAL PSYCHOGERIATRICS, 25 S137-S138, Oct, 2013
BASIC ASPECTS OF ALCOHOL USE DISORDER COMORBID WITH DEPRESSIVE DISORDER

E. Hashimoto, W. Ukai, T. Ishii, Y. Kigawa, T. Yoshinaga, K. Watanabe, T. Shirasaka, M. Tateno, S. Kobayashi, T. Saito

ALCOHOL AND ALCOHOLISM, 48 28-28, Sep, 2013
UNDERSTANDING OF MECHANISMS UNDERLYING BRAIN ABNORMALITY IN FASD AND ITS TRANSLATIONAL APPROACH

W. Ukai, E. Hashimoto, T. Shirasaka, T. Ishii, T. Yoshinaga, Y. Kigawa, M. Tateno, S. Kobayashi, T. Saito

ALCOHOL AND ALCOHOLISM, 48 19-19, Sep, 2013
統合失調症の成体脳神経産生機構に対する薬物・細胞投与の影響に関する研究

鵜飼渉, 金田博雄, 橋本恵理, 木川昌康, 白坂知彦, 石井貴男, 今井智之, 小林清樹, 吉永敏弘, 館農勝 …

統合失調症研究, 3(1), 2013
Two-layer appearance on brain perfusion SPECT in idiopathic normal pressure hydrocephalus: A qualitative analysis by using easy Z-score imaging system, eZIS

Seiju Kobayashi, Masaru Tateno, Kumiko Utsumi, Hidetoshi Morii, Toshikazu Saito

ASIA-PACIFIC PSYCHIATRY, 4 140-140, Oct, 2012
INTRAVENOUS NEURAL STEM CELL TRANSPLANTATION - A STRATEGY FOR FACILITATION OF NEURAL NETWORK AND BEHAVIORAL RECOVERY

T. Shirasaka, W. Ukai, E. Hashimoto, H. Kaneta, T. Igarashi, Y. Kigawa, K. Watanabe, T. Ishii, T. Yoshinaga, S. Kobayashi …

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 36 110A-110A, Sep, 2012
BDNF AS A POTENTIALBIOMARKER FOR FETAL ALCOHOL EFFECTS- COMPARATIVE STUDY OF SERUM CONSENTRATIONS IN RAT MODEL

T. Igarashi, K. Watanabe, W. Ukai, E. Hashimoto, T. Shirasaka, H. Kaneta, Y. Kigawa, T. Ishii, T. Yoshinaga, S. Kobayashi …

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 36 120A-120A, Sep, 2012
統合失調症の脳神経回路修復薬物・細胞コンバインド療法の可能性の検討

鵜飼渉, 小野貴文, 橋本恵理, 金田博雄, 白坂知彦, 五十嵐健史, 木川昌康, 渡邊公彦, 吉永敏弘, 石井貴男 …

日本生物学的精神医学会誌, 23(2) 109-114, 2012 Peer-reviewed
My life and Work.

10 32-33, 2011 Invited
内科医にも可能な認知症の診断と治療.

小林清樹

札幌市内科医会会報, 18 15-21, 2011 Invited
石灰沈着を伴うびまん性神経原線維変化病(DNTC)が疑われた1例-最新の画像診断技術を用いた機能画像所見を含めて-

小林清樹, 齊藤正樹, 館農勝, 内海久美子, 古瀬勉, 森井秀俊, 齋藤利和

精神科, 18(2) 223-233, 2011 Peer-reviewedInvited
Apolipoprotein E4 frequencies of dementia with Lewy bodies and Alzheimer's disease

Japanese journal of geriatric psychiatry, 21(2) 253-260, Feb, 2010
Tips for effective presentation.

9 12-12, 2010 Invited

Presentations

Comparison of the Usefulness of Brain Perfusion SPECT, DAT-SPECT, and MIBG Scintigraphy for the Diagnosis of Dementia with Lewy Bodies.

Seiju Kobayashi, Kanae Makino, Shigeki Hatakeyama, Tomo Iwamoto, Kumiko Utsumi, Chiaki Kawanishi

23rd International Symposium on Molecular Medicine, Mar 28, 2019
A long-term care community network to support people with dementia.

Seiju Kobayashi, Tomo Iwamoto, Masaru Tateno, Kumiko Utsumi, Chiaki Kawanishi

Korean Neuropsychiatry Association Annual meeting 2018, Apr, 2018
Comparison of the Usefulness of Brain Perfusion SPECT, DAT-SPECT, and MIBG Scintigraphy for the Diagnosis of Dementia with Lewy Bodies.

Seiju Kobayashi, Kanae Makino, Shigeki Hatakeyama, Tomo Iwamoto, Kumiko Utsumi, Chiaki Kawanishi

American Association for Geriatric Psychiatry 2018 Annual Meeting, Mar, 2018
The Usefulness of Combined Brain Perfusion SPECT, DAT-SPECT, and MIBG Scintigraphy for the Diagnosis of Dementia with Lewy Bodies.

Seiju Kobayashi, Kanae Makino, Shigeki Hatakeyama, Tomo Iwamoto, Hanako Tsujino, Wataru Ukai, Eri Hashimoto, Kumiko Utsumi, Chiaki Kawanishi

17th Global Neuroscience Conference, Oct, 2017
A long-term care community network to support people with dementia.

Seiju Kobayashi, Masaru Tateno, Tomo Iwamoto, Kumiko Utsumi, Chiaki Kawanishi

2017 Asia Pacific Meeting of WAPR, Sep, 2017
The Usefulness of Combined Brain Perfusion SPECT, DAT-SPECT, and MIBG Scintigraphy for the Diagnosis of Dementia with Lewy Bodies.

Seiju Kobayashi, Kanae Makino, Shigeki Hatakeyama, Tomo Iwamoto, Hanako Tsujino, Wataru Ukai, Tomonori Murayama, Eri Hashimoto, Kumiko Utsumi, Chiaki Kawanishi

Korean Association for Geriatric Psychiatry(KAGP), Nov 18, 2016 Invited
認知症における性差の影響

小林清樹

日本性差医学・医療学会学術集会, Jan, 2016 Invited
The usefulness of a blood flow analyzing program eZIS in the differential diagnosis between idiopathic Normal Pressure Hydrocephalus and Alzheimer’s disease.

Seiju Kobayashi, Masaru Tateno, Kumiko Utsumi, Tomo Iwamoto, Hidetoshi Morii, Chiaki Kawanishi

Asia-Pacific Conference Alzheimer's Disease International, Nov, 2015
A community network to support people with dementia.

Seiju Kobayashi, Masaru Tateno, Tomo Iwamoto, Kumiko Utsumi, Chiaki Kawanishi

World Congress of the World Association for Psychosocial Rehabilitation, Nov, 2015
The effect of Apolipoprotein E ε4 allele on the morphological and functional neuroimaging in late onset Alzheimer’s disease.

Seiju Kobayashi, Masaru Tateno, Kumiko Utsumi, Hitoshi Sohma, Yasuo Kokai, Yoichi M. Ito, Hidetoshi Morii, Chiaki Kawanishi

World Molecular Imaging Congress, Sep, 2015
A long-term care community network to support people with dementia.

Seiju Kobayashi, Masaru Tateno, Tomo Iwamoto, Kumiko Utsumi, Chiaki Kawanishi

WPA regional Congress, Jun, 2015 Invited
Apolipoprotein E4 in a Japanese population with Alzheimer's disease and dementia with Lewy bodies.

Kobayashi S, Tateno M, Tae Woo Park, Utsumi K, Sohma H, Yoichi M. Ito, Kokai Y, Saito T

The 14th the International College of Geriatric Psychoneuropharmacology, Oct 1, 2014
Apolipoprotein E4 frequencies in a Japanese population with Alzheimer's disease and dementia with Lewy bodies.

Kobayashi S, Tateno M, Tae Woo Park, Utsumi K, Sohma H, Yoichi M. Ito, Kokai Y, Saito T

The 16th International Psychogeriatrics Association Congress (IPA ), Oct 1, 2013
Comparison of the Usefulness of Brain Perfusion SPECT and MIBG Myocardial Scintigraphy for the Diagnosis of Dementia with Lewy Bodies.

Kobayashi S, Tateno M, Utsumi K, Morii H, Saito T

The 4th World Congress of Asian Psychiatry (WCAP), Aug 20, 2013
Apolipoprotein E4 in a Japanese population with Alzheimer's disease and dementia with Lewy bodies.

Kobayashi S, Tateno M, Tae Woo Park, Utsumi K, Sohma H, Yoichi M. Ito, Kokai Y, Saito T

Alzheimer's Association International Conference(AAIC), Jul 13, 2013
A long-term care community model to support people with dementia: the Naka-sorachi local network.

Kobayashi S, Tateno M, Utsumi K, Saito T

The 20th World Congress of the International Association of Gerontology and Geriatrics（IAGG), Jun 23, 2013
Two-Layer Appearance on Brain Perfusion SPECT in Idiopathic Normal Pressure Hydrocephalus.

Kobayashi S, Tateno M, Utsumi K, Morii H, Saito T

The 28th International Conference of Alzheimer’s Disease International (ADI), Apr 18, 2013
Two-Layer Appearance on Brain Perfusion SPECT in Idiopathic Normal Pressure Hydrocephalus: A Qualitative Analysis by Using Easy Z-Score Imaging System, eZIS.

Kobayashi S, Tateno M, Utsumi K, Morii H, Saito T

15th Pacific Rim College of Psychiatrists Socientific Meeting, Oct 25, 2012
Multiple support system for elderly people with Dementia.

Kobayashi S, Tateno M, Utsumi K, Saito T

International Psychogeriatrics Association International meeting, Sep 7, 2012
123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy and brain perfusion SPECT in dementia with Lewy bodies (DLB)

Kobayashi S, Tateno M, Utsumi K, Saito T

7th Taiwanese Society of Geriatric Psychiatry annual meeting, Apr 1, 2012 Invited

Teaching Experience

精神科 (札幌医科大学附属病院,五稜会病院,砂川市立病院,中江病院)

Professional Memberships

Research Projects

The application to the elucidation of pathology and the treatment of DLB focusing the gender difference

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2021 - Mar, 2024
DAT-SPECTを用いたレビー小体型認知症の症状発現の解明および新たな治療応用

科学研究費補助金(基盤研究(C)), 文部科学省, Apr, 2017 - Mar, 2020

小林清樹
レビー小体型認知症におけるレム睡眠行動障害の診断・治療法の応用

科学研究費補助金(若手研究(B)), 文部科学省, Apr, 2014 - Mar, 2016

小林清樹
レビー小体型認知症における診断マーカー

科学研究費補助金(若手研究(B)), 文部科学省, Apr, 2010 - Mar, 2012

小林清樹

Academic Activities

個人相談コーナー

札幌市医師会, May 12, 2018 - May 12, 2018

Social Activities

ただのもの忘れ？認知症？～診断と治療、その前に予防～

Lecturer

札幌市・札幌認知症の人と家族の会, 認知症の人を正しく理解する研修会, Sep 19, 2019 - Sep 19, 2019
認知症の予防と気づき～100歳まで元気に過ごすために～

Lecturer

札幌市医師会,さっぽろ北部認知症連携の会, 認知症市民フォーラム, Jul 7, 2019 - Jul 7, 2019
認知症の診断・治療・予防

Lecturer

札幌医科大学, 先端医学公開講座, Jan 16, 2016 - Jan 16, 2016
うつ病～老人性うつを中心に～

Lecturer

中央老人福祉センター, 健康講話, Nov 29, 2011 - Nov 29, 2011
認知症の診断・治療・ケア

Lecturer

江差町, 第4回江差町健康セミナー心の健康・脳の健康, Aug 19, 2011 - Aug 19, 2011

Media Coverage

単なる物忘れか、認知症によるものか、見分けるのは難しい

北海道新聞オントナ, Oct, 2008 Newspaper, magazine

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