2021年4月
Regio- and stereoselective synthesis of cyclobutanes by nickel-catalyzed homodimerizative [2 + 2] cycloaddition using allenamides
Tetrahedron Letters
- ,
- ,
- ,
- 巻
- 69
- 号
- 開始ページ
- 152974
- 終了ページ
- 152974
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.tetlet.2021.152974
- 出版者・発行元
- Elsevier {BV}
Highly regio- and stereoselective homodimerizative [2 + 2] cycloaddition of allenamides under nickel catalysis was developed. Xantphos is an essential ligand to give “tail to tail” products and DFT studies revealed that oxidative addition between a nickel(0) complex and two distal C[dbnd]C bonds of the allenamides would be a key process. Sequential formation of the metallacycle intermediate would proceed in both a regio- and stereoselective manner to give the corresponding cyclobutane as a single isomer.
- リンク情報
- ID情報
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- DOI : 10.1016/j.tetlet.2021.152974
- ISSN : 0040-4039
- eISSN : 1873-3581
- ORCIDのPut Code : 101295687
- SCOPUS ID : 85102866449