2005年4月
Chlorotrimethylsilane as a mild and effective source of acid catalyst in reductive benzylation
CHEMISTRY LETTERS
- ,
- 巻
- 34
- 号
- 4
- 開始ページ
- 594
- 終了ページ
- 595
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1246/cl.2005.594
- 出版者・発行元
- CHEMICAL SOC JAPAN
New reductive benzylation of hydroxy functions was effected by using the combination of benzaldehyde, TMSCl, and Et3SiH. TMSCl first reacts with alcohols to form HCl, which is probably the ultimate catalyst for this reaction system. TMSCl can also trap water and thus effectively promote dehydration reactions when more than stoichiometric amount of TMSCl is used. Although excess TMSCl was required for the foregoing reactions, TMSCl could be readily removed by simple evaporation.
- リンク情報
- ID情報
-
- DOI : 10.1246/cl.2005.594
- ISSN : 0366-7022
- eISSN : 1348-0715
- Web of Science ID : WOS:000228541600069