Kiyoshi Nakahara

Profile Information

Affiliation: Professor, Research Center for Brain Communication, Kochi University of Technology (KUT)
: (Concurrent)Professor, School of Informatics
: Kochi University

Degree: PhD(Kyoto University)

Researcher number: 50372363
ORCID ID: https://orcid.org/0000-0001-6701-6216
J-GLOBAL ID: 201101088772361670
researchmap Member ID: B000219037

External link: https://sites.google.com/view/nakahara-lab

Our lab is based in Research Center for Brain Communication (BrainCom) at Kochi University of Technology (KUT).

We use fMRI, EEG, TMS, tA/DCS in human participants, as well as high-density ECoG in non-human primates (macaques and marmosets), to explore the dynamics of brain activity that supports our cognitive functions.

Research Areas

Papers

Multimodal deep neural decoding reveals highly resolved spatiotemporal profile of visual object representation in humans

Noriya Watanabe, Kosuke Miyoshi, Koji Jimura, Daisuke Shimane, Ruedeerat Keerativittayayut, Kiyoshi Nakahara, Masaki Takeda

NeuroImage, 275 120164, Jul 15, 2023 Peer-reviewed
The Stroop effect involves an excitatory–inhibitory fronto–cerebellar loop

Moe Okayasu, Tensei Inukai, Daiki Tanaka, Kaho Tsumura, Reiko Shintaki, Masaki Takeda, Kiyoshi Nakahara, Koji Jimura

Nature Communications, 14(27), Jan 11, 2023 Peer-reviewed
Perceptual uncertainty alternates top-down and bottom-up fronto-temporal network signaling during response inhibition

Kaho Tsumura, Reiko Shintaki, Masaki Takeda, Junichi Chikazoe, Kiyoshi Nakahara, Koji Jimura

The Journal of Neuroscience, 42(22) 4567-4579, Jun 1, 2022 Peer-reviewed
Reversible Fronto-occipitotemporal Signaling Complements Task Encoding and Switching under Ambiguous Cues

Kaho Tsumura, Keita Kosugi, Yoshiki Hattori, Ryuta Aoki, Masaki Takeda, Junichi Chikazoe, Kiyoshi Nakahara, Koji Jimura

Cerebral Cortex, 32(9) 1911-1931, May 1, 2022 Peer-reviewed
Decoding distributed oscillatory signals driven by memory and perception in the prefrontal cortex

Hisashi Tanigawa, Kei Majima, Ren Takei, Keisuke Kawasaki, Hirohito Sawahata, Kiyoshi Nakahara, Atsuhiko Iijima, Takafumi Suzuki, Yukiyasu Kamitani, Isao Hasegawa

Cell Reports, 39(2) 110676-110676, Apr, 2022 Peer-reviewed
Executive control by fronto-parietal activity explains counterintuitive decision behavior in complex value-based decision-making

Teppei Matsui, Yoshiki Hattori, Kaho Tsumura, Ryuta Aoki, Masaki Takeda, Kiyoshi Nakahara, Koji Jimura

NeuroImage, 249 118892, Apr, 2022 Peer-reviewed
Cross-hemispheric complementary prefrontal mechanisms during task switching under perceptual uncertainty

Kaho Tsumura, Ryuta Aoki, Masaki Takeda, Kiyoshi Nakahara, Koji Jimura

The Journal of Neuroscience, 41(10) 2197-2213, Mar 10, 2021 Peer-reviewed
Functional heterogeneity in the left lateral posterior parietal cortex during visual and haptic crossmodal dot-surface matching

Jiajia Yang, Yinghua Yu, Hiroaki Shigemasu, Hiroshi Kadota, Kiyoshi Nakahara, Takanori Kochiyama, Yoshimichi Ejima, Jinglong Wu

Brain and Behavior, e02033, Jan 19, 2021 Peer-reviewed
Development of a self-paced sequential letterstring reading task to capture the temporal dynamics of reading a natural language

Kasedo Ryutaro, Iijima Atsuhiko, Nakahara Kiyoshi, Adachi Yusuke, Hasegawa Isao

Advanced Biomedical Engineering, 10 26-31, 2021 Peer-reviewed
Self-controlled choice arises from dynamic prefrontal signals that enable future anticipation

Daiki Tanaka, Ryuta Aoki, Shinsuke Suzuki, Masaki Takeda, Kiyoshi Nakahara, Koji Jimura

The Journal of Neuroscience, 40(50) 9736-9750, Dec 9, 2020 Peer-reviewed
Elucidating the role of the posterior medial frontal cortex in social conflict processing.

Wake SJ, Aoki R, Nakahara K, Izuma K

Neuropsychologia, 132 107124-107124, Sep, 2019 Peer-reviewed
Neural signals in amygdala predict implicit prejudice toward an ethnic outgroup.

Izuma K, Aoki R, Shibata K, Nakahara K

NeuroImage, 189 341-352, Apr, 2019 Peer-reviewed
Locally induced neuronal synchrony precisely propagates to specific cortical areas without rhythm distortion

Haruo Toda, Keisuke Kawasaki, Sho Sato, Masao Horie, Kiyoshi Nakahara, Asim K. Bepari, Hirohito Sawahata, Takafumi Suzuki, Haruo Okado, Hirohide Takebayashi …

Scientific Reports, 8(1) 7678, Dec 1, 2018 Peer-reviewed
Large-scale network integration in the human brain tracks temporal fluctuations in memory encoding performance.

Keerativittayayut R, Aoki R, Sarabi MT, Jimura K, Nakahara K

eLife, 7, Jun, 2018 Peer-reviewedLast authorCorresponding author
Visual perceptual training reconfigures post-task resting-state functional connectivity with a feature-representation region

Mitra Taghizadeh Sarabi, Ryuta Aoki, Kaho Tsumura, Ruedeerat Keerativittayayut, Koji Jimura, Kiyoshi Nakahara

PLoS ONE, 13(5) e0196866, May 1, 2018 Peer-reviewedLast authorCorresponding author
Altered KYN/TRP, Gln/Glu, and Met/methionine sulfoxide ratios in the blood plasma of medication-free patients with major depressive disorder

Hidehiro Umehara, Shusuke Numata, Shin-ya Watanabe, Yutaka Hatakeyama, Makoto Kinoshita, Yukiko Tomioka, Kiyoshi Nakahara, Takeshi Nikawa, Tetsuro Ohmori

Scientific Reports, 7(1) 4855, Jul, 2017 Peer-reviewed
Associative-memory representations emerge as shared spatial patterns of theta activity spanning the primate temporal cortex

Kiyoshi Nakahara, Ken Adachi, Keisuke Kawasaki, Takeshi Matsuo, Hirohito Sawahata, Kei Majima, Masaki Takeda, Sayaka Sugiyama, Ryota Nakata, Atsuhiko Iijima …

Nature Communications, 7 11827, Jun, 2016 Peer-reviewedLead authorCorresponding author
LOCAL AND RETROGRADE GENE TRANSFER INTO PRIMATE NEURONAL PATHWAYS VIA ADENO-ASSOCIATED VIRUS SEROTYPE 8 AND 9

Y. Masamizu, T. Okada, K. Kawasaki, H. Ishibashi, S. Yuasa, S. Takeda, I. Hasegawa, K. Nakahara

Neuroscience, 193 249-258, Oct, 2011 Peer-reviewedLast authorCorresponding author
Intrasulcal electrocorticography in macaque monkeys with minimally invasive neurosurgical protocols

Takeshi Matsuo, Keisuke Kawasaki, Takahiro Osada, Hirohito Sawahata, Takafumi Suzuki, Masahiro Shibata, Naohisa Miyakawa, Kiyoshi Nakahara, Atsuhiko Iijima, Noboru Sato …

Frontiers in Systems Neuroscience, 5(2011) 34, May 12, 2011 Peer-reviewed
Efficient gene transfer into neurons in monkey brain by adeno-associated virus 8

Yoshito Masamizu, Takashi Okada, Hidetoshi Ishibashi, Shin&apos, ichi Takeda, Shigeki Yuasa, Kiyoshi Nakahara

Neuroreport, 21(6) 447-451, Apr, 2010 Peer-reviewedLast authorCorresponding author

Misc.

Multi-modal deep neural decoding of visual object representation in humans

Noriya Watanabe, Kosuke Miyoshi, Koji Jimura, Daisuke Shimane, Ruedeerat Keerativittayayut, Kiyoshi Nakahara, Masaki Takeda

bioRxiv, Apr 10, 2022
An excitatory-inhibitory fronto-cerebellar loop resolves the Stroop effect

Moe Okayasu, Tensei Inukai, Daiki Tanaka, Kaho Tsumura, Maho Hosono, Reiko Shintaki, Masaki Takeda, Kiyoshi Nakahara, Koji Jimura

bioRxiv, Jan 20, 2022
学際領域研究の拠点形成に向けて — 脳コミュニケーション研究センターの2020 年度の活動—

門田宏, 岩田誠, 繁桝博昭, 竹田昂典, 竹田真己, 松崎公紀, 吉田真一, 渡邊言也, 王瑞敏, 中原潔

高知工科大学紀要, 18(1) 147-156, Dec 28, 2021 Last author
Perceptual uncertainty alternates top-down and bottom-up fronto-temporal network signaling during response inhibition

Kaho Tsumura, Reiko Shintaki, Masaki Takeda, Junichi Chikazoe, Kiyoshi Nakahara, Koji Jimura

bioRxiv, Dec 28, 2021
硬膜上高密度多点電極を用いたサル一次視覚野における網膜視野の再構成

土屋貴大, 飯島淳彦, 川嵜圭祐, 鈴木隆文, 長谷川功, 中原潔

日本生理学雑誌, 82(1) 11-12, Feb, 2020
1文字連続呈示課題を用いた文理解中の2重構造化処理に寄与する神経基盤の解明

加世堂竜太郎, 飯島淳彦, 中原潔, 足立雄哉, 長谷川功

日本生理学雑誌, 82(1) 12-12, Feb, 2020
うつ病患者の血漿におけるキヌレニン/トリプトファン比、グルタミン/グルタミン酸比、メチオニン/メチオニンスルホキシド比

梅原英裕, 渡部真也, 木下誠, 富岡有紀子, 中瀧理仁, 畠山豊, 中原潔, 二川健, 沼田周助, 大森哲郎

日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集, 28回・48回 151-151, Nov, 2018
難治性うつ病に対する電気けいれん治療によるBDNF遺伝子メチル化と安静時fMRIの変動

森信繁, 須賀楓介, 澤田健, 木村岳裕, 門田宏, 中原潔, 岩田誠, 淵上学, 岡田怜, 岡田剛 …

先進医薬研究振興財団研究成果報告集, 2015年度 52-53, Mar, 2016
Intrasulcal electrocorticography in macaque monkeys

Kawasaki Keisuke, Matsuo Takeshi, Osada Takahiro, Sawahata Hirohito, Suzuki Takafumi, Shibata Masahiro, Miyakawa Naohisa, Nakahara Kiyoshi, Sato Noboru, Kawai Kensuke …

NEUROSCIENCE RESEARCH, 71 E413-E414, 2011 Peer-reviewed
Gene transfer into the primate central nervous system via antero- and retrograde infections by adeno-associated viruses

Masamizu Yoshito, Okada Takashi, Kawasaki Keisuke, Ishibashi Hidetoshi, Takeda Shin'ichi, Yuasa Shigeki, Hasegawa Isao, Nakahara Kiyoshi

NEUROSCIENCE RESEARCH, 68 E219, 2010 Peer-reviewed
A non-magnetic mini-manipulator for an MRI-based method for localization of a microelectrode tip within monkey cerebral cortex

Koyano Kenji W, Ohashi Yohei, Matsui Teppei, Takeda Masaki, Nakahara Kiyoshi, Naya Yuji, Koyama Minoru, Watanabe Tomomi, Miyashita Yasushi

Proceedings of Annual Meeting of the Physiological Society of Japan, 2007 071-071, 2007 Peer-reviewed
Localization of a microelectrode tip within the monkey temporal cortex using high-resolution MRI

Kenji W. Koyano, Teppei Matsui, Yuji Naya, Minoru Koyama, Masaki Takeda, Kiyoshi Nakahara, Yasushi Miyashita

NEUROSCIENCE RESEARCH, 55 S71-S71, 2006
Functional magnetic resonance imaging of macaque monkeys

K Nakahara

IMAGING IN BIOLOGICAL RESEARCH, PT A, 385 84-90, 2004 Peer-reviewed
An fMRI study of Wisconsin Card Sorting Test: Transient activation in inferior prefrontal cortex time-locked to dimensional shift, and its load-dependent increase

Konishi S, Nakajima K, Uchida I, Kameyama M, Nakahara K, Sekihara K, Miyashita Y

NeuroImage, 7(4 PART II), 1998 Peer-reviewed

Presentations

脳広域ネットワークのダイナミクスー記憶記銘・表象・想起との関係

中原潔

第４７回日本神経心理学会学術集会・シンポジウム５「脳機能ネットワークの知見とその臨床への展開可能性」, Sep 8, 2023 Invited

Professional Memberships

Research Projects

非侵襲的かつ脳深部へ適応可能な新規刺激法を用いたヒト記憶脳回路の解明

科学研究費助成事業, 挑戦的研究(開拓), 日本学術振興会, Jul, 2021 - Mar, 2025

竹田真己, 中原潔, 長谷川功, 地村弘二, 渡邊言也
記憶形成を促進する睡眠中の脳回路メカニズムの因果的解明

科学研究費助成事業, 基盤研究(A), 日本学術振興会, Apr, 2020 - Mar, 2024

竹田真己, 中原潔, 長谷川功, 地村弘二, 渡邊言也
Brain organization for theory-of-mind and letter recognition-like behaviors in macaques—comparing homology with humans

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2023
Investigation of functional roles of ongoing brain activity in cognition and consciousness

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2021

Nakahara Kiyoshi
Reactivation of memory representation by pattern stimulation of the brain

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Research (Pioneering), Japan Society for the Promotion of Science, Jun, 2017 - Mar, 2020

Nakahara Kiyoshi
In-brain imaging analysis of spastic dysphonia by fMRI and development for treatment method development

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

Hirose Kahori
Neural mechanisms for the formation of self-controll choice preference

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

Jimura Koji
Exploration of brain activation patterns as memory engrams

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Nakahara Kiyoshi
Central neuroregulatory imaging on swallowing and therapeutic strategy for swallowing disorder based on brain plasticity

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Hyodo Masamitsu, NAGAO Asuka, NAKAHIRA Maya, NISHI Kouhei, YANOGAWA Taiki, YANO Minako
Neural mechanisms of visual communications revealed with electrocorticography.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

Hasegawa Isao, SUZUKI Takafumi, TODA Haruo, KAWASAKI Keisuke, IIJIMA Atsuhiko, NISHIYAMA Yuta
Research on memory retrieval mechanisms in the primate medial temporal lobe using high-density electrocorticography

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2017

Kiyoshi Nakahara, SAWAHATA Hirohito, ADACHI Ken
Exploration of relationship between gamma-band activity and memory function in the temporal lobe

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

Nakahara Kiyoshi, ADACHI Ken
Study of rodent "face areas" with high-densitity electrocorticogram and optogenetics

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

TODA Haruo, TANIGAWA Hisashi, NAKAHARA Kiyoshi
Neural mechanism of flexible cognition and use of symbols: a comparative macaque ECoG and human fMRI study

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2014

HASEGAWA ISAO, NAKAHARA Kiyoshi, KITAGAWA Junichi, KAWASAKI Keisuke
Optogenetic control of macaque temporal neurons

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2010 - 2012

NAKAHARA Kiyoshi, OKADA Takashi
Higy- resolution MRI-aided analysis of cortical circuit in monkey brains

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2005 - 2007

NAKAHARA Kiyoshi

Industrial Property Rights

特開2017-113182 MR画像の超解像化システム

岩田誠, 松崎公紀, 中原潔, 吉田真一, 繁桝博昭, 門田宏, 木村岳裕, 青木隆太, 朴啓彰, 森信繁