Safe and robust batteries are urgently requested today for power sources of electric vehicles. Thus, a growing interest has been noted for fabricating those with solid electrolytes. Materials search by density functional theory (DFT) methods offers great promise for finding new solid electrolytes but the evaluation is known to be computationally expensive, particularly on ion migration property. In this work, we proposed a Bayesian-optimization-driven DFT-based approach to efficiently screen for compounds with low ion migration energies (Eb). We demonstrated this on 318 tavorite-type Li- and Nacontaining compounds. We found that the scheme only requires ∼30% of the total DFT-Eb evaluations on the average to recover the optimal compound ∼90% of the time. Its recovery performance for desired compounds in the tavorite search space is ∼2× more than random search (i.e., for Eb &lt
0.3 eV). Our approach offers a promising way for addressing computational bottlenecks in large-scale material screening for fast ionic conductors.