2019年4月1日
Chronic brain blood-flow imaging device for a behavioral experiment using mice.
Biomedical optics express
- 巻
- 10
- 号
- 4
- 開始ページ
- 1557
- 終了ページ
- 1566
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1364/BOE.10.001557
A chronic brain blood-flow imaging device was developed for cerebrovascular disease treatment. This device comprises a small complementary metal-oxide semiconductor image sensor and a chronic fiber-optic plate window on a mouse head. A long-term cerebral blood-flow imaging technique was established in a freely moving mouse. Brain surface images were visible for one month using the chronic FOP window. This device obtained brain surface images and blood-flow velocity. The blood-flow changes were measured in behavioral experiments using this device. The chronic brain blood-flow imaging device may contribute to determining the cause of cerebrovascular disease and the development of cerebrovascular disease treatment.
- リンク情報
- ID情報
-
- DOI : 10.1364/BOE.10.001557
- PubMed ID : 31086694
- PubMed Central 記事ID : PMC6484972