Haruhiro Higashida

Biosynthesis and Function of VIP and Oxytocin: Mechanisms of C-terminal Amidation, Oxytocin Secretion and Transport.

Hideto Yonekura, Ichiro Kato, Yasuhiko Yamamoto, Takayuki Ikeda, Haruhiro Higashida, Hiroshi Okamoto

Endocrinology, 164(9), Aug 1, 2023

Postnatal expression of CD38 in astrocytes regulates synapse formation and adult social memory.

Tsuyoshi Hattori, Stanislav M Cherepanov, Ryo Sakaga, Jureepon Roboon, Dinh Thi Nguyen, Hiroshi Ishii, Mika Takarada-Iemata, Takumi Nishiuchi, Takayuki Kannon, Kazuyoshi Hosomichi …

The EMBO journal, 42(15) e111247, Jun 26, 2023

Oral Supplementation with Maca Improves Social Recognition Deficits in the Valproic Acid Animal Model of Autism Spectrum Disorder.

Pinyue Fu, Shuxin Luo, Zhongyu Liu, Kazumi Furuhara, Takahiro Tsuji, Haruhiro Higashida, Shigeru Yokoyama, Jing Zhong, Chiharu Tsuji

Brain sciences, 13(2), Feb 13, 2023

Two oxytocin analogs, N-(p-fluorobenzyl) glycine and N-(3-hydroxypropyl) glycine, induce uterine contractions ex vivo in ways that differ from that of oxytocin

Stanislav M. Cherepanov, David Desseauve, Teruko Yuhi, Takashi Iizuka, Takashi Hosono, Masanori Ono, Hiroshi Fujiwara, Shigeru Yokoyama, Satoshi Shuto, Haruhiro Higashida

PLOS ONE, 18(2) e0281363, Feb 9, 2023 Peer-reviewed

Infant Stimulation Induced a Rapid Increase in Maternal Salivary Oxytocin.

Kana Minami, Teruko Yuhi, Haruhiro Higashida, Shigeru Yokoyama, Takahiro Tsuji, Chiharu Tsuji

Brain sciences, 12(9), Sep 15, 2022

Early-onset of social communication and locomotion activity in F2 pups of a valproic acid-induced mouse model of autism.

Chiharu Tsuji, Kazumi Furuhara, Ryuko Mizutani, Kana Minami, Pinyue Fu, Jing Zhong, Haruhiro Higashida, Shigeru Yokoyama, Takahiro Tsuji

Neuroscience letters, 788 136827-136827, Aug 6, 2022

Receptor for advanced glycation end-products and child neglect in mice: A possible link to postpartum depression

Haruhiro Higashida, Maria Gerasimenko, Yasuhiko Yamamoto

Comprehensive Psychoneuroendocrinology, 11 100146-100146, Aug, 2022

Oxytocin Dynamics in the Body and Brain Regulated by the Receptor for Advanced Glycation End-Products, CD38, CD157, and Nicotinamide Riboside

Haruhiro Higashida, Kazumi Furuhara, Olga Lopatina, Maria Gerasimenko, Osamu Hori, Tsuyoshi Hattori, Yasuhiko Hayashi, Stanislav M. Cherepanov, Anna A. Shabalova, Alla B. Salmina …

Frontiers in Neuroscience, 16, Jul 7, 2022

Dual Nature of RAGE in Host Reaction and Nurturing the Mother-Infant Bond.

Yu Oshima, Ai Harashima, Seiichi Munesue, Kumi Kimura, Nontaphat Leerach, Hisanori Goto, Mariko Tanaka, Akane Niimura, Kenjiro Hayashi, Hiroshi Yamamoto …

International journal of molecular sciences, 23(4), Feb 14, 2022

Oral Supplementation with L-Carnosine Attenuates Social Recognition Deficits in CD157KO Mice via Oxytocin Release.

Takahiro Tsuji, Kazumi Furuhara, Maria Gerasimenko, Anna Shabalova, Stanislav M Cherepanov, Kana Minami, Haruhiro Higashida, Chiharu Tsuji

Nutrients, 14(4), Feb 14, 2022

Use of Cocultures to Measure the Blood-Brain Barrier Permeability of Oxytocin.

Yasuhiko Yamamoto, Ai Harashima, Sei-Ichi Munesue, Haruhiro Higashida

Methods in molecular biology (Clifton, N.J.), 2384 247-255, 2022

An improved sample extraction method reveals that plasma receptor for advanced glycation end-products (RAGE) modulates circulating free oxytocin in mice.

Stanislav M Cherepanov, Maria Gerasimenko, Teruko Yuhi, Anna Shabalova, Hong Zhu, Shigeru Yokoyama, Alla B Salmina, Shei-Ichi Munesue, Ai Harashima, Yasuhiko Yamamoto …

Peptides, 146 170649-170649, Dec, 2021

Receptor for advanced glycation end-products (RAGE) plays a critical role in retrieval behavior of mother mice at early postpartum.

Maria Gerasimenko, Olga Lopatina, Seiichi Munesue, Ai Harashima, Shigeru Yokoyama, Yasuhiko Yamamoto, Haruhiro Higashida

Physiology & behavior, 235 113395-113395, Jun 1, 2021

Experimental Attempt on Walking Behavior and Stress Assessment in a Completely Darkened Tunnel

Miho Seike, Nobuyoshi Kawabata, Masato Hasegawa, Chiharu Tsuji, Haruhiro Higashida, Teruko Yuhi

Infrastructures, 6(5) 75-75, May 13, 2021

Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism.

Stanislav M Cherepanov, Maria Gerasimenko, Teruko Yuhi, Kazumi Furuhara, Chiharu Tsuji, Shigeru Yokoyama, Keiichi I Nakayama, Masaaki Nishiyama, Haruhiro Higashida

BMC neuroscience, 22(1) 32-32, May 1, 2021

Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD.

Jureepon Roboon, Tsuyoshi Hattori, Hiroshi Ishii, Mika Takarada-Iemata, Dinh Thi Nguyen, Collin D Heer, Denis O'Meally, Charles Brenner, Yasuhiko Yamamoto, Hiroshi Okamoto …

Journal of neurochemistry, 158(2) 311-327, Apr 19, 2021

Transport of oxytocin to the brain after peripheral administration by membrane-bound or soluble forms of receptors for advanced glycation end-products.

Sei-Ichi Munesue, MingKun Liang, Ai Harashima, Jing Zhong, Kazumi Furuhara, Elizabeta B Boitsova, Stanislav M Cherepanov, Maria Gerasimenko, Teruko Yuhi, Yasuhiko Yamamoto …

Journal of neuroendocrinology, 33(3) e12963, Mar, 2021

A huggable device can reduce the stress of calling an unfamiliar person on the phone for individuals with ASD.

Hidenobu Sumioka, Hirokazu Kumazaki, Taro Muramatsu, Yuichiro Yoshikawa, Hiroshi Ishiguro, Haruhiro Higashida, Teruko Yuhi, Masaru Mimura

PloS one, 16(7) e0254675, 2021

Oxytocin-Trust Link in Oxytocin-Sensitive Participants and Those Without Autistic Traits.

Hirofumi Kurokawa, Yusuke Kinari, Hiroko Okudaira, Kiyotaka Tsubouchi, Yoshimichi Sai, Mitsuru Kikuchi, Haruhiro Higashida, Fumio Ohtake

Frontiers in neuroscience, 15 659737-659737, 2021

Glycation reaction and the role of the receptor for advanced glycation end-products in immunity and social behavior.

Nontaphat Leerach, Ai Harashima, Seiichi Munesue, Kumi Kimura, Yu Oshima, Hisanori Goto, Hiroshi Yamamoto, Haruhiro Higashida, Yasuhiko Yamamoto

Glycoconjugate journal, 38(3) 303-310, Oct 27, 2020

Papers

Menu

Coauthors