2001年8月
Expression of vinexin alpha in the dorsal half of the eye and in the cardiac outflow tract and atrioventricular canal
MECHANISMS OF DEVELOPMENT
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- 巻
- 106
- 号
- 1-2
- 開始ページ
- 147
- 終了ページ
- 150
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/S0925-4773(01)00421-X
- 出版者・発行元
- ELSEVIER SCIENCE BV
Vinexin, a recently identified cytoskeletal protein, contains three SH3 domains and plays important roles in regulation of cytoskeletal organization and signal transduction. Using whole-mount in situ hybridization, we showed here that expression of vinexin alpha, the longer vinexin transcript, is strictly regulated, although the shorter transcript, vinexin beta, is expressed almost ubiquitously during embryonic development in mice. Expression of vinexin alpha was limited to within part of the eye and heart in 10.5 dpc embryos. Analysis of cryosections of 10.5 dpc embryos showed that vinexin alpha was expressed in a dorsal half of the retinal pigment epithelium and in the outflow tract and atrioventricular canal of the heart. Furthermore, we also found that vinexin a was expressed in the gonad and in a ventral part of the pons of 12.5 dpc embryos. These results indicated that the expression of vinexin et is strictly regulated in a temporally and spatially restricted manner. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
- リンク情報
- ID情報
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- DOI : 10.1016/S0925-4773(01)00421-X
- ISSN : 0925-4773
- PubMed ID : 11472845
- Web of Science ID : WOS:000170370900015