1997年7月
A telomerase mutant defective in sister chromatid separation at mitosis
BIOESSAYS
- ,
- 巻
- 19
- 号
- 7
- 開始ページ
- 557
- 終了ページ
- 559
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1002/bies.950190706
- 出版者・発行元
- COMPANY OF BIOLOGISTS LTD
The telomere is a functional domain of the chromosome, located at the extreme ends, and is essential for normal chromosome stability. Chromosomes lacking telomeres are inherited improperly, and mutations in the telomeric repeat sequences are thought to lead to senescence and possibly to cancer. The molecular mechanisms maintaining chromosomes by telomeres, however, have been unclear. Results recently reported by Kirk et al.((1)) offer an insight into new telomerase function. They have identified a novel telomerase mutation that blocks sister chromatid separation in mitosis.
- リンク情報
- ID情報
-
- DOI : 10.1002/bies.950190706
- ISSN : 0265-9247
- PubMed ID : 9230688
- Web of Science ID : WOS:A1997XK26200005