2010年11月
Optimization of silica surface with nanosize holes for immobilization of biomolecules and analysis of their interactions
ANALYTICA CHIMICA ACTA
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- 巻
- 680
- 号
- 1-2
- 開始ページ
- 72
- 終了ページ
- 78
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/j.aca.2010.09.028
- 出版者・発行元
- ELSEVIER SCIENCE BV
An evanescent-field-coupled waveguide-mode sensor of the Kretschmann configuration with a silica waveguide having nanoscale holes is an ideal tool for detection of bimolecular reactions. In the present research, an optimized surface of the sensor with cylindrical nanoscale holes was modified with sodium (1-{[6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]oxy}-2,5-dioxopyrrolidine-3-sulfonate) (Sulfo-EMCS) to facilitate the attachment of biomolecules; the resulting surface could be cleaned for reuse simply by changing the pH of the buffering solution. The modification is expected to be useful for wide range of molecular detection. (C) 2010 Elsevier B.V. All rights reserved.
- リンク情報
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- DOI
- https://doi.org/10.1016/j.aca.2010.09.028
- CiNii Articles
- http://ci.nii.ac.jp/naid/80021428894
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/20969994
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000284385800011&DestApp=WOS_CPL
- ID情報
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- DOI : 10.1016/j.aca.2010.09.028
- ISSN : 0003-2670
- CiNii Articles ID : 80021428894
- PubMed ID : 20969994
- Web of Science ID : WOS:000284385800011