1999年
ヘテロ分岐シクロデキストリンの合成とその性質
応用糖質科学 : oyo toshitsu kagaku = Journal of applied glycoscience
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- 巻
- 46
- 号
- 2
- 開始ページ
- 217
- 終了ページ
- 225
- 記述言語
- 日本語
- 掲載種別
- DOI
- 10.5458/jag.46.217
- 出版者・発行元
- The Japanese Society of Applied Glycoscience
Hetero-branched cyclodextrins (CDs) were synthesized by transglycosylation or the reverse action of several enzymes such as βββ-galactosidases, α-galactosidases, α-mannosidases, lysozyme and R-Nacetylhexosaminidase. Their structures were analyzed by methylation, FAB-MS, and NMR spectroscopies. β-Galactosidase and a-galactosidase from microorganisms synthesized hetero-branched CDs, of which the galactose residues were linked at side chains of the branched CDs. But these enzymes could not synthesize galactosyl-CDs, directly linked to the CD ring. However, α-galactosidase from coffee bean and α-mannosidase and N-acetylhexosaminidase from jack bean could bind galactosyl, mannosyl and N-acetylglucosaminyl residues directly to the CD rings, respectively, by transglycosylation or reverse action. The effects of the side-chain residues in branched CDs, on solubility, hemolytic activity, and inclusion reactions with 6-O-α-D-glucosyl-CDs, 6-O-α-D-galactosyl-CDs, and 6-O-α-Dmannosyl-CDs, were examined.
- リンク情報
- ID情報
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- DOI : 10.5458/jag.46.217
- ISSN : 1344-7882
- ISSN : 1880-7291
- CiNii Articles ID : 10008259068
- CiNii Books ID : AN10453916