2017年
Arterial Stiffness is an Independent Risk Factor for Anemia After Percutaneous Native Kidney Biopsy
KIDNEY & BLOOD PRESSURE RESEARCH
- 巻
- 42
- 号
- 2
- 開始ページ
- 284
- 終了ページ
- 293
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1159/000477453
- 出版者・発行元
- KARGER
Background/Aims: Bleeding is the most common complication after renal biopsy. Although numerous predictors of bleeding have been reported, it remains unclear whether arterial stiffness affects bleeding complications. Method: We performed an observational study of the renal biopsies performed in our division over an approximately 6-year period (May 2010 to May 2016). The clinical and laboratory factors were analyzed to reveal the risk factors associated with bleeding, with a focus on anemia (defined as a >= 10% decrease in hemoglobin [Hb] after biopsy). The brachial-ankle pulse wave velocity (baPWV) was measured to evaluate arterial stiffness. Results: This study included 462 patients (male, n=244; female, n=218). Anemia (defined above) was observed in 54 patients (11.7%). The risk of anemia was higher in women, older patients, and patients with lower serum albumin, lower eGFR and lower diastolic blood pressure after biopsy. We then performed a further analysis of 187 patients whose baPWV data were available. Multivariate analysis revealed that a higher baPWV was an independent risk factor for anemia. ROC analysis for predicting anemia found that a baPWV value of 1839 cm/s had the best performance (AUC 0.689). Conclusion: An increased baPWV may be a more valuable predictor of bleeding than any of the other reported risk factors. (C) 2017 The Author(s) Published by S. Karger AG, Basel
- リンク情報
-
- DOI
- https://doi.org/10.1159/000477453
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000404365300009&DestApp=WOS_CPL
- URL
- https://www.ncbi.nlm.nih.gov/pubmed/28531895
- URL
- http://orcid.org/0000-0003-1468-5170
- ID情報
-
- DOI : 10.1159/000477453
- ISSN : 1420-4096
- eISSN : 1423-0143
- ORCIDのPut Code : 43365855
- Web of Science ID : WOS:000404365300009