Makiko Shimizu - My portal - researchmap

Profile Information

Affiliation: Faculty of Pharmaceutical Sciences, Department of Bio-Pharmacy, Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University

Degree: (BLANK)
博士(昭和薬科大学)

J-GLOBAL ID: 200901090699096218
researchmap Member ID: 1000242976

Research Interests

2

Research Areas

3

Misc.

20

Possibility of influence of midazolam sedation on the diagnosis of brain death: Concentration of active metabolites after cessation of midazolam.

YAKUGAKU ZASSHI, 123 (9) 811, 2003
Correlation between the physicochemical property of some nonsteroidal anti-inflammatory drugs and changes in adenosine triphosphate, glutathione and hemoglobin in rat erythrocytes.

Biol. Pharm. Bull, 26(8) 1155, 2003
Effects of aspirin and/or salicylate on hydrolysis and glucuronidation of indomethacin in rat erythrocytes and hepatocytes.

Biol. Pharm. Bull., 26(5) 675, 2003
医師は薬剤師に何を望んでいるか，―評価される薬剤師とは―

薬学雑誌, 123 (3) 173, 2003
Glucuronidation of propofol and its analogs by human and rat liver microsomes.

Biol Pharm Bull., 26(2) 216, 2003
Testicular toxicity of mono-n-butyl phthalate and related phthalates on bound iron in rat red blood cells

Nobuo Watanabe, Makiko Shimizu, Yoshiaki Matsumoto, Masamichi Fukuoka

Journal of Health Science, 48(6) 527-533, Dec, 2002
Testicular toxicity of mone-n-Butyl Phthalate and related Phthalate on bound Iron in rat red blood cells

Journal of Health Science, 48(6), 527, 2002
Possible origin of rat testicular atropny induced by Di-n-Butyl Phtatate: Changes in the activities of some enzymes during rat testis perfusion under a hypoxic cordition and with hone-n-Butyl Phthalate

Journal of Health Science, 48(6), 503, 2002
Sulfation of bisphene/A abolished its estrogenicity based on proliferation and gene expression in human breast cancer MCF-7 cells

Toxicology in Vitro, 16(5), 549, 2002
Possible origin of rat testicular atropny induced by Di-n-Butyl Phtatate: Changes in the activities of some enzymes during rat testis perfusion under a hypoxic cordition and with hone-n-Butyl Phthalate

Journal of Health Science, 48(6), 503, 2002
Sulfation of bisphene/A abolished its estrogenicity based on proliferation and gene expression in human breast cancer MCF-7 cells

Toxicology in Vitro, 16(5), 549, 2002
PK/PDモデリングの考え方

TDM研究, 18(1) 6, 2001
Simultaneous modeling of pharmacokinetics and pharmacodynamics

The japanese Journal of therapeutic drug monitoring, 18(1) 6, 2001
Practical Application of Pharmacokinetic-Pharmacodynamic Modeling.

MATSUMOTO Yoshiaki, SHIMIZU Makiko, FUKUOKA Masamichi

Drug Metabolism and Pharmacokinetics, 15(5) 452-460, 2000
Genetic Polymorphism of Human Tissue Phenol Sulfotransferases

OZAWA Shogo, SHIMIZU Makiko, MATSUMOTO Yoshiaki, FUKUOKA Masamichi, KATO Takahiko, OHNO Yasuo

15(2) 171-176, 2000
Practical application of pharmacokinetic-pharmacodynamic modeling

Yoshiaki MATSUMOTO, Makiko SHIMIZU, Masamichi FUKUOKA

Xenobiotic metabolism and disposition, 15(5) 452-460, 2000
Genetic polymorphism of human tissue phenol sulfotransferases

Shogo OZAWA, Makiko SHIMIZU, Yoshiaki MATSUMOTO, Masamichi FUKUOKA, Takahiko KATO, Yasuo OHNO

Xenobiotic metabolism and disposition, 15(2) 171-176, 2000
Metabolic activation of ο-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone : role of human CYP1A2 and rat CYP2C11/CYP2E1

Xenobiotica, 30(10) 1005-1017, 2000
A computer program for pharmacokinetics based on maximum likelihood estimation using the gamma distribution with a probability density function : comparison with the normal distribution.

Koji TANIKAWA, Yoshiaki MATSUMOTO, Takashi MATSUZAKI, Makiko SHIMIZU, Mitsuo MATSUMOTO, Masamichi FUKUOKA

Biol. Pharm. Bull., 23(2) 235-239, 2000
Sulfating-activity and stability of cDNA-expressed allozymes of human phenol sulfotransferase, ST1A3*1 ((213)Arg) and ST1A3*2 ((213)His), both of which exist in Japanese as well as Caucasians

S Ozawa, M Shimizu, T Katoh, A Miyajima, Y Ohno, Y Matsumoto, M Fukuoka, YM Tang, NP Lang, FF Kadlubar

JOURNAL OF BIOCHEMISTRY, 126(2) 271-277, Aug, 1999

Professional Memberships

3

Research Projects

3