2005年12月
Development of useful reactions based on the novel reactivities of allenic compounds and their application to tandem cyclizations
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
- 巻
- 125
- 号
- 12
- 開始ページ
- 899
- 終了ページ
- 925
- 記述言語
- 日本語
- 掲載種別
- DOI
- 10.1248/yakushi.125.899
- 出版者・発行元
- PHARMACEUTICAL SOC JAPAN
This review highlights a recent study on allenic compounds by the author's group. In the first section, the organocopper-mediated ring-opening reaction of ethynylaziridines and palladium-catalyzed reductive synthesis of allenes are described. In the second section, palladium-catalyzed stereoselective cyclization of allenes, including the tandem reaction, leading to aziridines, pyrrolidines, benzoisoindoles, and cyclopropanes is presented. The final section reviews aziridination and medium-ring formation due to the intramolecular reaction of bromoallenes. The latter reaction is based on the author's recent discovery that bromoallenes can act as allylic dication equivalents in the presence of a palladium catalyst and alcohol.
- リンク情報
- ID情報
-
- DOI : 10.1248/yakushi.125.899
- ISSN : 0031-6903
- PubMed ID : 16327237
- Web of Science ID : WOS:000234103600001