Yoshinaka Murai - My portal

Profile Information

Affiliation: Associate Professor, School of Medicine, Dpt. of Physiology, Kurume University

Degree: PhD(Mar, 1998, Kyushu University)

J-GLOBAL ID: 200901064443576475
researchmap Member ID: 1000309290

External link: http://www.med.kurume-u.ac.jp/med/physiol1/index.html

Research Interests

Research Areas

Research History

Education

- 1998

Kyushu University
- 1998

Graduate School, Division of Medical Sciences, Kyushu University

Committee Memberships

2006

- 日本生理学会評議委員

Papers

Activation of cathepsin L contributes to the irreversible depolarization induced by oxygen and glucose deprivation in rat hippocampal CA1 neurons

Shogo Kikuta, Yoshinaka Murai, Eiichiro Tanaka

NEUROSCIENCE LETTERS, 636 120-126, Jan, 2017 Peer-reviewed
Clinical Trials in Acute Ischemic Stroke

Kiyoshi Kikuchi, Eiichiro Tanaka, Yoshinaka Murai, Salunya Tancharoen

CNS DRUGS, 28(10) 929-938, Oct, 2014 Peer-reviewed
Potential of the Angiotensin Receptor Blockers (ARBs) Telmisartan, Irbesartan, and Candesartan for Inhibiting the HMGB1/RAGE Axis in Prevention and Acute Treatment of Stroke

Kiyoshi Kikuchi, Salunya Tancharoen, Takashi Ito, Yoko Morimoto-Yamashita, Naoki Miura, Ko-ichi Kawahara, Ikuro Maruyama, Yoshinaka Murai, Eiichiro Tanaka

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 14(9) 18899-18924, Sep, 2013 Peer-reviewed
Edaravone (Radicut), a free radical scavenger, is a potentially useful addition to thrombolytic therapy in patients with acute ischemic stroke.

Kikuchi K, Miura N, Kawahara KI, Murai Y, Morioka M, Lapchak PA, Tanaka E

Biomedical reports, 1(1) 7-12, Jan, 2013 Peer-reviewed
Clinical Neuroprotective Drugs for Treatment and Prevention of Stroke

Kiyoshi Kikuchi, Hisaaki Uchikado, Motohiro Morioka, Yoshinaka Murai, Eiichiro Tanaka

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 13(6) 7739-7761, Jun, 2012 Peer-reviewed
Two opposing roles of 4-AP-sensitive K+ current in initiation and invasion of spikes in rat mesencephalic trigeminal neurons

Mitsuru Saito, Yoshinaka Murai, Hajime Sato, Yong-Chul Bae, Tadashi Akaike, Masahiko Takada, Youngnam Kang

JOURNAL OF NEUROPHYSIOLOGY, 96(4) 1887-1901, Oct, 2006 Peer-reviewed

Misc.

The efficacy of edaravone (radicut), a free radical scavenger, for cardiovascular disease

Kikuchi K, Tancharoen S, Takeshige N, Yoshitomi M, Morioka M, Murai Y, Tanaka E

Int J Mol Sci., 14 18899-18924, Jul 1, 2013 Peer-reviewed
Activation of protein kinase A and C prevents recovery from persistent depolarization produced by oxygen and glucose deprivation in rat hippocampal neurons

Y. Murai, Y. Okabe, E. Tanaka

JOURNAL OF NEUROPHYSIOLOGY, 107(9) 2517-2525, May, 2012 Peer-reviewed
Neural development of methyl-CpG-binding protein 2 null embryonic stem cells: A system for studying Rett syndrome

Yasunori Okabe, Akira Kusaga, Tomoyuki Takahashi, Chiaki Mitsumasu, Yoshinaka Murai, Eiichiro Tanaka, Hideho Higashi, Toyojiro Matsuishi, Ken-ichiro Kosai

BRAIN RESEARCH, 1360 17-27, Nov, 2010 Peer-reviewed
Thiamylal antagonizes the inhibitory effects of dorsal column stimulation on dorsal horn activities in humans

Eiichiro Tanaka, Toshiyuki Tobita, Yoshinaka Murai, Yasunori Okabe, Aya Yamada, Tatsuhiko Kano, Hideho Higashi, Koki Shimoji

NEUROSCIENCE RESEARCH, 64(4) 391-396, Aug, 2009 Peer-reviewed
Two opposing roles of 4-AP-sensitive K+ current in initiation and invasion of spikes in rat mesencephalic trigeminal neurons

Mitsuru Saito, Yoshinaka Murai, Hajime Sato, Yong-Chul Bae, Tadashi Akaike, Masahiko Takada, Youngnam Kang

JOURNAL OF NEUROPHYSIOLOGY, 96(4) 1887-1901, Oct, 2006 Peer-reviewed
Neuroprotective mechanisms of lidocaine against in vitro ischemic insult of the rat hippocampal CA1 pyramidal neurons

S Niiyama, E Tanaka, S Tsuji, Y Murai, M Satani, H Sakamoto, K Takahashi, M Kuroiwa, A Yamada, M Noguchi …

NEUROSCIENCE RESEARCH, 53(3) 271-278, Nov, 2005
Neuroprotective mechanisms of lidocaine against in vitro ischemic insult of the rat hippocampal CA1 pyramidal neurons

S Niiyama, E Tanaka, S Tsuji, Y Murai, M Satani, H Sakamoto, K Takahashi, M Kuroiwa, A Yamada, M Noguchi …

NEUROSCIENCE RESEARCH, 53(3) 271-278, Nov, 2005
Excitatory GABAergic synaptic potentials in the mesencephalic trigerninal nucleus of adult rat in vitro

Y Yokomizo, Y Murai, E Tanaka, H Inokuchi, J Kusukawa, H Higashi

NEUROSCIENCE RESEARCH, 51(4) 463-474, Apr, 2005
Excitatory GABAergic synaptic potentials in the mesencephalic trigerninal nucleus of adult rat in vitro

Y Yokomizo, Y Murai, E Tanaka, H Inokuchi, J Kusukawa, H Higashi

NEUROSCIENCE RESEARCH, 51(4) 463-474, Apr, 2005
Orexins cause depolarization via nonselective cationic and K+ channels in isolated locus coeruleus neurons

Y Murai, T Akaike

NEUROSCIENCE RESEARCH, 51(1) 55-65, Jan, 2005
Orexins cause depolarization via nonselective cationic and K+ channels in isolated locus coeruleus neurons

Y Murai, T Akaike

NEUROSCIENCE RESEARCH, 51(1) 55-65, Jan, 2005
Functional, metabolic, and histological changes of vascular tissues after warm ischemia.

Moriyama. S, Utoh. J, Murai. Y, Hagiwara. S, Kunitomo. R, Nishi. K, Kitamura. N

Ann Thorac Cardiovasc Surg., 7 143-149, 2001
Noradrenaline receptor-mediated potentiation of caffeine-induced Ca2+-activated K+ currents in bovine ciliary muscle cells

T Okuda, N Tokutomi, Y Tokutomi, Y Murai, A Negi, K Nishi

CURRENT EYE RESEARCH, 23(6) 455-462, 2001
Functional, metabolic, and histological changes of vascular tissues after warm ischemia.

Moriyama. S, Utoh. J, Murai. Y, Hagiwara. S, Kunitomo. R, Nishi. K, Kitamura. N

Ann Thorac Cardiovasc Surg., 7 143-149, 2001
Noradrenaline receptor-mediated potentiation of caffeine-induced Ca2+-activated K+ currents in bovine ciliary muscle cells

T Okuda, N Tokutomi, Y Tokutomi, Y Murai, A Negi, K Nishi

CURRENT EYE RESEARCH, 23(6) 455-462, 2001
The prostaglandin E series modulates high-voltage-activated calcium channels probably through the EP3 receptor in rat paratracheal ganglia

Y Ito, Y Murai, H Ishibashi, H Onoue, N Akaike

NEUROPHARMACOLOGY, 39(2) 181-190, 2000
Preferential inhibition of L- and N-type calcium channels in the rat hippocampal neurons by cilnidipine

Y Murai, H Uneyama, H Ishibashi, K Takahama, N Akaike

BRAIN RESEARCH, 854(1-2) 6-10, Jan, 2000
The prostaglandin E series modulates high-voltage-activated calcium channels probably through the EP3 receptor in rat paratracheal ganglia

Y Ito, Y Murai, H Ishibashi, H Onoue, N Akaike

NEUROPHARMACOLOGY, 39(2) 181-190, 2000
Preferential inhibition of L- and N-type calcium channels in the rat hippocampal neurons by cilnidipine

Y Murai, H Uneyama, H Ishibashi, K Takahama, N Akaike

BRAIN RESEARCH, 854(1-2) 6-10, Jan, 2000
Effect of nilvadipine on the voltage-dependent Ca2+ channels in rat hippocampal CA1 pyramidal neurons

H Ishibashi, Y Murai, N Akaike

BRAIN RESEARCH, 813(1) 121-127, Nov, 1998

Teaching Experience

Professional Memberships

Works

Research Projects

統合失調症の発現過程にオキシトシンはどのように関与するのか

科研費基盤C（一般）, 日本学術振興会, Apr, 2014 - Mar, 2016

村井恵良
統合失調症の発現に関わる前頭前野および扁桃体に対するモノアミンの作用

科研費基盤C（一般）, 日本学術振興会, Apr, 2011 - Mar, 2013

田中永一郎
Generation of iPS cells derived form an Rett syndrome model mouse and drug screening for Rett syndrome using MeCP2 deficient iPS cells

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2010 - 2012

TAKAHASHI Tomoyuki, MATSUISHI Toyojiro, TANAKA Eiichiro, MURAI Yoshinaka, NISHI Yoshihiro, OKABE Yasunori
Health effect evaluation based on characteristics of nanoparticles

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2007 - 2009

ISHIHARA Yoko, HAGIWARA Hiromi, ARAI Masataka, TANAKA Eiichiro, HASEGAWA Go, KOYAMA Satoshi, NISHI Yoshihiro, MURAI Yoshinaka
Dose aromatase regulate the feeding behavior and induce the sexual difference on appetite?

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2007 - 2008

NISHI Yoshihiro, KAWAHARA Yukie, NONOSHITA Akiko, ISHIHARA Yoko, TAJIRI Yuji, MIFUNE Hiroharu, TANAKA Eiichiro, MURAI Yoshinaka, NAGAYAMA Masayo
虚血性神経細胞死に関与する細胞内機序

2008
Activation of protein kinase A contributes to the persistent depolarization induced by in vitro ischemia

2008
Do androgen receptors contribute to the expression of sex differences in the brain?

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2006 - 2007

TANAKA Eiichiro, NISHI Yoshihiro, MURAI Yoshinaka
機械的単離法を用いた三叉神経中脳路核ニューロンのシナプス電流解析

2002
GABAergic synaptic responses recorded from neurons in rat mesencephalic trigeminal nucleus in vitro

2002
三叉神経中脳路核ニューロンの活動電位生成に対するA型K⁺チャネルの関与

2001
A role of A-type K⁺ channel in regulation of spike generation in Rat mesencephalic trigeminal neurons

2001