1989年
Nasal T-Cell Lymphoma Associated with Double Gammopathy; a Case Report
Practica Oto-Rhino-Laryngologica
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- 巻
- 82
- 号
- 12
- 開始ページ
- 1739
- 終了ページ
- 1744
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.5631/jibirin.82.1739
Nasal T-cell lymphoma associated with double gammopathy (IgG and IgA) was found in a 78-year-old man with a necrotic tumor in his right nasal cavity. He was treated with radiotherapy and CVP chemotherapy but the lymphoma relapsed in his left nasal cavity 1 year later. He was treated again with the same therapy and is now alive and tumor-free. Two serum M-components (IgG and IgA) were detected through his clinical course. To our knowledge, this is the first report of T-cell lymphoma associated with double gammopathy. The significance of M-components in T-cell lymphocytic proliferation remains unclear, but it may be that the M-components appear because of the inappropriate regulation of the T-B immune-response system in the presence of T-cell lymphoma. Histology in this case is also noteworthy. The first nasal tumor showed granulation and necrotic tissue with plasma cell infiltration
it was diagnosed as non-Hodgkin diffuse lymphoma, mixed type, by surface marker analysis. This indicates that immuno-histochemical study is indispensable for the diagnosis of nasal non-healing granuloma with necrosis. © 1989, The Society of Practical Otolaryngology. All rights reserved.
it was diagnosed as non-Hodgkin diffuse lymphoma, mixed type, by surface marker analysis. This indicates that immuno-histochemical study is indispensable for the diagnosis of nasal non-healing granuloma with necrosis. © 1989, The Society of Practical Otolaryngology. All rights reserved.
- ID情報
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- DOI : 10.5631/jibirin.82.1739
- ISSN : 0032-6313
- SCOPUS ID : 85007965899