MASAHIDE YAZAKI - My portal

Profile Information

Affiliation: Professor, Interdisciplinary Cluster for Cutting Edge Research, Institute for Biomedical Sciences , Department of Biological Sciences for Intractable Neurological Diseases, Shinshu University

Degree: 医学博士(Mar, 1998, 信州大学大学院)

J-GLOBAL ID: 200901012319231125
researchmap Member ID: 5000069642

Research Areas

Research History

Apr, 2017

School of Medicine, Department of Health Sciences, Shinshu University
Apr, 2017

信州大学バイオメディカル研究所教授
Apr, 2014

准教授、部門長

Education

Apr, 1994 - Mar, 1998

Shinshu University

Awards

2014

公益財団ホクト生物科学振興財団研究奨励賞, 公益財団ホクト生物科学振興財団

Papers

181

Therapeutic Outcome of Lenalidomide-dexamethasone in Patients with Relapsed or Refractory Systemic Immunoglobulin Light Chain (AL) Amyloidosis : A Single-center Analysis and Review of the Literature

Ueno Akihiro, Katoh Nagaaki, Ezawa Naoki, Yoshinaga Tsuneaki, Yazaki Masahide, Sekijima Yoshiki

Shinshu Medical Journal, 70(1) 29-38, Feb, 2022
Somatostatin-derived amyloid deposition associated with duodenal neuroendocrine tumour (NET): a report of novel localised amyloidosis associated with NET

Ichimata, Shojiro, Katoh, Nagaaki, Abe, Ryuta, Yoshinaga, Tsuneaki, Kametani, Fuyuki, Yazaki, Masahide, Kusama, Yukiko, Sano, Kenji, Uehara, Takeshi, Sekijima, Yoshiki

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 29(1) 64-65, 2022
Reversible Leukoencephalopathy in a Man with Childhood-onset Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome

Hoshino, Yumi, Kodaira, Minori, Matsuno, Atsuhiro, Kaneko, Tomoki, Fukuyama, Tetsuhiro, Takano, Kyoko, Yazaki, Masahide, Sekijima, Yoshiki

INTERNAL MEDICINE, 61(4) 553-557, 2022
Novel histopathological deposition patterns of EGF-containing fibulin-like extracellular matrix protein 1 amyloidosis: an autopsy case exhibiting a possible association between AEFEMP1 amyloidosis and elastic fibres

Ichimata, Shojiro, Hata, Yukiko, Katoh, Nagaaki, Kametani, Fuyuki, Yazaki, Masahide, Sekijima, Yoshiki, Nishida, Naoki

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 29(2) 139-140, 2022
A case of asymmetric insulin-derived localised amyloid deposition associated with long-acting insulin analog administration

Hirai, Keiji, Imamura, Shigeki, Hirai, Aizan, Umemoto, Naoka, Oshiro, Hisashi, Kametani, Fuyuki, Katoh, Nagaaki, Yazaki, Masahide, Ookawara, Susumu, Morishita, Yoshiyuki

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 29(3) 205-207, 2022
AH amyloid neuropathy: a novel clinical phenotype confirmed by histopathology and mass spectrometry

Ohashi, Nobuhiko, Katoh, Nagaaki, Kasuga, Kazuki, Yoshinaga, Tsuneaki, Kametani, Fuyuki, Yazaki, Masahide, Sekijima, Yoshiki

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 29(2) 141-142, 2022
CSF/plasma levels, transthyretin stabilisation and safety of multiple doses of tolcapone in subjects with hereditary ATTR amyloidosis

Takahashi, Yusuke, Ohashi, Nobuhiko, Takasone, Ken, Yoshinaga, Tsuneaki, Yazaki, Masahide, Roberts, Michael, Glidden, Paul F., Sekijima, Yoshiki

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 29(3) 190-196, 2022
Food Preferences of Patients with Citrin Deficiency

Okamoto, Miki, Okano, Yoshiyuki, Okano, Mai, Yazaki, Masahide, Inui, Ayano, Ohura, Toshihiro, Murayama, Kei, Watanabe, Yoriko, Tokuhara, Daisuke, Takeshima, Yasuhiro

NUTRIENTS, 13(9) 3123, Sep, 2021
Analysis of daily energy, protein, fat, and carbohydrate intake in citrin-deficient patients: Towards prevention of adult-onset type II citrullinemia

Okano, Yoshiyuki, Okamoto, Miki, Yazaki, Masahide, Inui, Ayano, Ohura, Toshihiro, Murayama, Kei, Watanabe, Yoriko, Tokuhara, Daisuke, Takeshima, Yasuhiro

MOLECULAR GENETICS AND METABOLISM, 133(1) 63-70, May, 2021
Hereditary Apolipoprotein A-1 Amyloidosis With Glu34Lys Mutation Treated by Liver Transplantation: A Case Report

Sagawa, Takaomi, Kogiso, Tomomi, Ito, Taito, Yasuda, Hideo, Katoh, Nagaaki, Yoshinaga, Tsuneaki, Yazaki, Masahide, Kato, Takaaki, Omori, Akiko, Kotera, Yoshihito …

TRANSPLANTATION PROCEEDINGS, 53(4) 1327-1332, May, 2021
Development of diagnostic antibodies against immunoglobulin heavy chain variable region for heavy chain amyloidosis (AH amyloidosis)

Nakagawa, Mayuko, Yazaki, Masahide, Kametani, Fuyuki, Katoh, Nagaaki, Yoshinaga, Tsuneaki, Higuchi, Keiichi, Sekijima, Yoshiki

PATHOLOGY INTERNATIONAL, 71(4) 245-254, Apr, 2021
A case of novel amyloidosis: glucagon-derived amyloid deposition associated with pancreatic neuroendocrine tumour

Ichimata, Shojiro, Katoh, Nagaaki, Abe, Ryuta, Yoshinaga, Tsuneaki, Kametani, Fuyuki, Yazaki, Masahide, Uehara, Takeshi, Ichimata, Shojiro, Sekijima, Yoshiki

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 28(1) 72-73, 2021
Dialysis-related amyloidosis associated with a novel beta(2)-microglobulin variant

Mizuno, Hiroki, Hoshino, Junichi, So, Masatomo, Kogure, Yuta, Fujii, Takeshi, Ubara, Yoshifumi, Takaichi, Kenmei, Nakaniwa, Tetsuko, Tanaka, Hideaki, Kurisu, Genji …

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 28(1) 42-49, 2021
Distribution of amyloidosis subtypes based on tissue biopsy site - Consecutive analysis of 729 patients at a single amyloidosis center in Japan

Abe, Ryuta, Katoh, Nagaaki, Takahashi, Yusuke, Takasone, Ken, Yoshinaga, Tsuneaki, Yazaki, Masahide, Kametani, Fuyuki, Sekijima, Yoshiki

PATHOLOGY INTERNATIONAL, 71(1) 70-79, Jan, 2021
Giant Hepatomegaly with Spleno-testicular Enlargement in a Patient with Apolipoprotein A-I Amyloidosis: An Uncommon Type of Amyloidosis in Japan

Yoshinaga, Tsuneaki, Katoh, Nagaaki, Yazaki, Masahide, Sato, Mitsuto, Kametani, Fuyuki, Yasuda, Hideo, Watanabe, Kyohei, Kawata, Kazuhito, Nakagawa, Mayuko, Sekijima, Yoshiki

INTERNAL MEDICINE, 60(4) 575-581, 2021
Late-onset Hereditary ATTR Amyloidosis with a Novel p.P63S (P43S) Transthyretin Variant

Aono, Yuya, Hamatani, Yasuhiro, Katoh, Nagaaki, Nakagawa, Mayuko, Nakamura, Katsuya, Yazaki, Masahide, Kametani, Fuyuki, Iguchi, Moritake, Murakami, Ikuko, Ogawa, Hisashi …

INTERNAL MEDICINE, 60(4) 557-561, 2021
Absolute quantitative analysis of cardiac amyloidosis using SPECT/CT with Tc-99m-pyrophosphate

Yanagisawa, Shin, Takahashi, Yusuke, Sasaki, Jun, Takasone, Ken, Yoshie, Koji, Koyama, Jun, Katoh, Nagaaki, Yazaki, Masahide, Kuwahara, Koichiro, Fujinaga, Yasunari …

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 28(3) 213-214, 2021
JCS 2020 Guideline on Diagnosis and Treatment of Cardiac Amyloidosis

Kitaoka, Hiroaki, Izumi, Chisato, Izumiya, Yasuhiro, Inomata, Takayuki, Ueda, Mitsuharu, Kubo, Toru, Koyama, Jun, Sano, Motoaki, Sekijima, Yoshiki, Tahara, Nobuhiro …

CIRCULATION JOURNAL, 84(9) 1610-1671, Sep, 2020
An autopsy case of amyloid tubulopathy exhibiting characteristic spheroid-type deposition

Ichimata, Shojiro, Hata, Yukiko, Abe, Ryuta, Yoshinaga, Tsuneaki, Katoh, Nagaaki, Kametani, Fuyuki, Yazaki, Masahide, Sekijima, Yoshiki, Ehara, Takashi, Nishida, Naoki

VIRCHOWS ARCHIV, 477(1) 157-163, Jul, 2020
Late-onset familial Mediterranean fever in Japan

Kishida, Dai, Yazaki, Masahide, Nakamura, Akinori, Tsuchiya-Suzuki, Ayako, Shimojima, Yasuhiro, Sekijima, Yoshiki

MODERN RHEUMATOLOGY, 30(3) 564-567, 2020

Books and Other Publications

池田修一編：アミロイドーシスの基礎と臨床

矢崎正英

金原出版，東京, 2005

Professional Memberships

Research Projects

成人型シトルリン血症患者に対する経口LOLAの有効性

受託研究, Citrin Foundation, Singapore, Jan, 2018 - Dec, 2020

矢﨑正英
ドミノ肝移植における医原性アミロイド伝播機構の解明

科学研究費補助金（基盤研究(C)）, Apr, 2017 - Mar, 2020

矢﨑正英
アミロイドーシスの統合病理学：伝播現象の把握から新たな治療法を探る

科学研究費補助金（基盤研究B）, Apr, 2017

樋口京一
シトリン欠損症におけるCTLN2発症・重篤化に関わる遺伝因子・環境因子の解明

科学研究費補助金（基盤研究C）, Apr, 2015

佐伯武賴
改良型レーザーカッターによるアミロイド物質の生体構造と機能解析

科学研究費補助金（挑戦的萌芽研究）, Apr, 2014

樋口京一
伝播現象から見たアミロイドーシスの実験病理学的把握と予防治療法の開発

科学研究費補助金（基盤研究B）, Apr, 2013

樋口京一
FAPにおける低分子薬剤のアミロイド線維沈着抑制機序の解明と根治治療への応用

科学研究費補助金（基盤研究(C)）, Apr, 2013

矢﨑正英
トランスサイレチンアミロイドーシスにおける中枢神経病変の発生機序とその治療

科学研究費補助金（若手研究(B)）, Apr, 2004

矢崎正英
免疫グロブリン重鎖アミロイドーシスの簡便な診断法の開発とアミロイド形成機序の解明

科学研究費補助金（基板研究C）

矢﨑正英
Laser micro-dissectionを用いた微量アミロイド蛋白のプロテオーム解析

その他の資金, 公益財団ホクト生物科学振興財団

矢﨑正英
amyloidosis