論文

査読有り
2018年1月1日

Range in systolic blood pressure and care-needs certification in long-term care insurance in community-dwelling older patients with chronic kidney disease

Journal of International Medical Research
  • Taroh Himeno
  • ,
  • Tazuo Okuno
  • ,
  • Keisuke Watanabe
  • ,
  • Kumie Nakajima
  • ,
  • Osamu Iritani
  • ,
  • Hiroshi Yano
  • ,
  • Takuro Morita
  • ,
  • Yuta Igarashi
  • ,
  • Masashi Okuro
  • ,
  • Shigeto Morimoto

46
1
開始ページ
293
終了ページ
306
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1177/0300060517721795
出版者・発行元
SAGE Publications Ltd

Objective: Low systolic blood pressure (SBP) is associated with an increased risk for cardiovascular morbidity/mortality in older patients with chronic kidney disease (CKD). The present study evaluated the association between range in blood pressure and first care-needs certification in the Long-term Care Insurance (LTCI) system or death in community-dwelling older subjects with or without CKD. Methods: CKD was defined as an estimated glomerular filtration rate &lt
60 ml/min/1.73 m2 or dipstick proteinuria of + or greater. Our study was conducted in 1078 older subjects aged 65–94 years. Associations were estimated using the Cox proportional hazards model. Results: During 5 years of follow-up, 135 first certifications and 53 deaths occurred. Among patients with CKD, moderate SBP (130–159 mmHg) was associated with a significantly lower adjusted risk of subsequent total certification (hazard ratio [HR] = 0.44) and subsequent certification owing to dementia (HR = 0.17) compared with SBP &lt
130 mmHg. These relationships were not observed in non-CKD subjects. Conclusion: Lower SBP of &lt
130 mmHg may predict a higher risk for subsequent first care-needs certification in LTCI, especially for dementia, in community-dwelling patients with CKD.

リンク情報
DOI
https://doi.org/10.1177/0300060517721795
URL
http://www.ncbi.nlm.nih.gov/pubmed/28835151
ID情報
  • DOI : 10.1177/0300060517721795
  • ISSN : 1473-2300
  • ISSN : 0300-0605
  • SCOPUS ID : 85041395527

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