2009年5月
Changes in Borna disease virus genome with adaptation to host
MICROBES AND INFECTION
- ,
- ,
- ,
- ,
- 巻
- 11
- 号
- 6-7
- 開始ページ
- 721
- 終了ページ
- 724
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/j.micinf.2009.03.011
- 出版者・発行元
- ELSEVIER SCIENCE BV
The CRNP5 variant of Borna disease virus (BDV) has stronger pathogenesis than the CRP3 variant in which only 4 nucleotides in the whole genome are different. The CRP3 is produced by 3 passages in rat brains of BDV, whereas the CRNP5 is produced by 5 passages in mouse brains after 2 passages in rat brains of the BDV. Thymidylic acids at nt 3608 and 3673 were replaced by cytidylic acids during 3 passages in mice. Three passages in mice caused replacement of adenylic acid at nt 7936 by guanylic acid. No replacement at nt 8742 occurred during passages in mice. (C) 2009 Elsevier Masson SAS. All rights reserved.
- リンク情報
- ID情報
-
- DOI : 10.1016/j.micinf.2009.03.011
- ISSN : 1286-4579
- Web of Science ID : WOS:000268423800012