2018年1月
A single-shot T-2 mapping protocol based on echo-split gradient-spin-echo acquisition and parametric multiplexed sensitivity encoding based on projection onto convex sets reconstruction
MAGNETIC RESONANCE IN MEDICINE
- ,
- ,
- ,
- 巻
- 79
- 号
- 1
- 開始ページ
- 383
- 終了ページ
- 393
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1002/mrm.26696
- 出版者・発行元
- WILEY
PurposeTo develop a high-speed T-2 mapping protocol that is capable of accurately measuring T-2 relaxation time constants from a single-shot acquisition.
TheoryA new echo-split single-shot gradient-spin-echo (GRASE) pulse sequence is developed to acquire multicontrast data while suppressing signals from most nonprimary echo pathways in Carr-Purcell-Meiboom-Gill (CPMG) echoes. Residual nonprimary pathway signals are taken into consideration when performing T-2 mapping using a parametric multiplexed sensitivity encoding based on projection onto convex sets (parametric-POCSMUSE) reconstruction method that incorporates extended phase graph modeling of GRASE signals.
MethodsThe single-shot echo-split GRASE-based T-2 mapping procedure was evaluated in human studies at 3 Tesla. The acquired data were compared with reference data obtained with a more time-consuming interleaved spin-echo echo planar imaging protocol. T-2 maps derived from conventional single-shot GRASE scans, in which nonprimary echo pathways were not appropriately addressed, were also evaluated.
ResultsUsing the developed single-shot T-2 mapping protocol, quantitatively accurate T-2 maps can be obtained with a short scan time (<0.2 seconds per slice).
ConclusionAccurate T-2 mapping with minimal signal contamination from CPMG high-order echo pathways can be achieved by the developed method that integrates single-shot echo-split GRASE acquisition and parametric-POCSMUSE reconstruction. Magn Reson Med 79:383-393, 2018. (c) 2017 International Society for Magnetic Resonance in Medicine.
TheoryA new echo-split single-shot gradient-spin-echo (GRASE) pulse sequence is developed to acquire multicontrast data while suppressing signals from most nonprimary echo pathways in Carr-Purcell-Meiboom-Gill (CPMG) echoes. Residual nonprimary pathway signals are taken into consideration when performing T-2 mapping using a parametric multiplexed sensitivity encoding based on projection onto convex sets (parametric-POCSMUSE) reconstruction method that incorporates extended phase graph modeling of GRASE signals.
MethodsThe single-shot echo-split GRASE-based T-2 mapping procedure was evaluated in human studies at 3 Tesla. The acquired data were compared with reference data obtained with a more time-consuming interleaved spin-echo echo planar imaging protocol. T-2 maps derived from conventional single-shot GRASE scans, in which nonprimary echo pathways were not appropriately addressed, were also evaluated.
ResultsUsing the developed single-shot T-2 mapping protocol, quantitatively accurate T-2 maps can be obtained with a short scan time (<0.2 seconds per slice).
ConclusionAccurate T-2 mapping with minimal signal contamination from CPMG high-order echo pathways can be achieved by the developed method that integrates single-shot echo-split GRASE acquisition and parametric-POCSMUSE reconstruction. Magn Reson Med 79:383-393, 2018. (c) 2017 International Society for Magnetic Resonance in Medicine.
- リンク情報
- ID情報
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- DOI : 10.1002/mrm.26696
- ISSN : 0740-3194
- eISSN : 1522-2594
- Web of Science ID : WOS:000417926300036