2013年7月
ATP depletion inhibits retraction of chromatophores induced by GABA in cephalopod Todarodes pacificus
FISHERIES SCIENCE
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- ,
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- 巻
- 79
- 号
- 4
- 開始ページ
- 605
- 終了ページ
- 610
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1007/s12562-013-0630-9
- 出版者・発行元
- SPRINGER JAPAN KK
Color changes in cephalopods are generated by the expansion or retraction of chromatophores located under the dermis. The behavior of the chromatophores is regulated by neurotransmitters; l-glutamate (l-Glu) is an excitatory transmitter that causes the chromatophores to expand. To date, serotonin [5-hydroxytryptamine (5-HT)] is the only neurotransmitter known to stimulate retraction of chromatophores. We found that the chromatophores in the Japanese squid Todarodes pacificus were regulated by gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, and that GABA caused expanded chromatophores to retract. We also found that adenosine 5'-triphosphate (ATP) concentrations in skin samples remained stable at their initial values for more than 24 h after the death of each squid; therefore, the chromatophores could respond to both l-Glu and GABA during that period. Furthermore, we attempted to reduce the levels of ATP by storing skin sample in sodium azide solution. The chromatophores in sodium azide-treated skin samples were induced to expand by l-Glu, but these expanded chromatophores could not be induced to retract by GABA. Based on these observations, we conclude that ATP is essential for retraction, but not expansion, of chromatophores.
- リンク情報
- ID情報
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- DOI : 10.1007/s12562-013-0630-9
- ISSN : 0919-9268
- Web of Science ID : WOS:000322008300007