Ryo Murakami

Profile Information

Affiliation: Epsilon Molecular Engineering co., ltd.

J-GLOBAL ID: 201801013429491382
researchmap Member ID: B000289899

Research Interests

Research Areas

Life sciences / Molecular biology /

Research History

Apr, 2021 - Present

主任研究員, 医薬開発事業部, 株式会社Epsilon Molecular Engineering
Mar, 2018 - Mar, 2021

Faculty of Science, Department of Biophysics and Biochemistry, The University of Tokyo
May, 2016 - Feb, 2018

特任研究員, 理学系研究科, 東京大学大学院
Apr, 2016 - Apr, 2016

Specialized Course of Life and Food Sciences, Graduate School of Science and Technology, Niigata University
Apr, 2015 - Mar, 2016

Specialized Course of Life and Food Sciences, Graduate School of Science and Technology, Niigata University

Education

Apr, 2013 - Mar, 2016

Specialized Course of Life and Food Sciences, Graduate School of Science and Technology, Niigata University
Apr, 2011 - Mar, 2013

Specialized Course of Life and Food Sciences, Graduate School of Science and Technology, Niigata University
Apr, 2007 - Mar, 2011

Department of Biology, Faculty of Science, Niigata University

Awards

Papers

Heterogeneous dissociation process of truncated RNAs by oligomerized Vasa helicase

Yoshimi Kinoshita, Ryo Murakami, Nao Muto, Shintaroh Kubo, Ryo Iizuka, Sotaro Uemura

Communications Biology, 4(1) 1386, Dec, 2021 Peer-reviewed
Structural insights into the Switching Off of the Interaction between the Archaeal Ribosomal Stalk and aEF1A by Nucleotide Exchange Factor aEF1B.

Takahiro Suzuki, Kosuke Ito, Tomohiro Miyoshi, Ryo Murakami, Toshio Uchiumi

Journal of molecular biology, 433(15) 167046-167046, Jul 23, 2021 Peer-reviewed
DEAD-box polypeptide 43 facilitates piRNA amplification by actively liberating RNA from Ago3-piRISC.

Ryo Murakami, Tetsutaro Sumiyoshi, Lumi Negishi, Mikiko C Siomi

EMBO reports, 22(4) e51313, Apr 7, 2021 Peer-reviewed
The Interaction between the Ribosomal Stalk Proteins and Translation Initiation Factor 5B Promotes Translation Initiation

Murakami R, Singh CR, Morris J, Tang L, Harmon I, Takasu A, Miyoshi T, Ito K, Asano K, Uchiumi

Molecular and Cellular Biology, 38(16), Jul, 2018 Peer-reviewed
Hierarchical roles of mitochondrial Papi and Zucchini in Bombyx germline piRNA biogenesis.

Kazumichi M Nishida, Kazuhiro Sakakibara, Yuka W Iwasaki, Hiromi Yamada, Ryo Murakami, Yukiko Murota, Takeshi Kawamura, Tatsuhiko Kodama, Haruhiko Siomi, Mikiko C Siomi

Nature, 555(7695) 260-264, Mar 8, 2018 Peer-reviewed
Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute

Tomohiro Miyoshi, Kosuke Ito, Ryo Murakami, Toshio Uchiumi

NATURE COMMUNICATIONS, 7 11846, Jun, 2016 Peer-reviewed
Crystal structure of translation initiation factor 5B from the crenarchaeon Aeropyrum pernix

Ryo Murakami, Tomohiro Miyoshi, Toshio Uchiumi, Kosuke Ito

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 84(5) 712-717, May, 2016 Peer-reviewed
Functional role of the C-terminal tail of the archaeal ribosomal stalk in recruitment of two elongation factors to the sarcin/ricin loop of 23S rRNA

Hirotatsu Imai, Tomohiro Miyoshi, Ryo Murakami, Kosuke Ito, Yoshizumi Ishino, Toshio Uchiumi

GENES TO CELLS, 20(7) 613-624, Jul, 2015 Peer-reviewed
Molecular insights into the interaction of the ribosomal stalk protein with elongation factor 1 alpha

Kosuke Ito, Takayoshi Honda, Takahiro Suzuki, Tomohiro Miyoshi, Ryo Murakami, Min Yao, Toshio Uchiumi

NUCLEIC ACIDS RESEARCH, 42(22) 14042-14052, Dec, 2014 Peer-reviewed
Structural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolase

Kosuke Ito, Ryo Murakami, Masahiro Mochizuki, Hao Qi, Yoshihiro Shimizu, Kin-ichiro Miura, Takuya Ueda, Toshio Uchiumi

NUCLEIC ACIDS RESEARCH, 40(20) 10521-10531, Nov, 2012 Peer-reviewed
Crystallization and preliminary X-ray analysis of peptidyl-tRNA hydrolase from Escherichia coli in complex with the acceptor-T?C domain of tRNA

Kosuke Ito, Hao Qi, Yoshihiro Shimizu, Ryo Murakami, Kin-ichiro Miura, Takuya Ueda, Toshio Uchiumi

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, 67(Pt 12) 1566-1569, Dec, 2011 Peer-reviewed

Books and Other Publications

生物工学会誌、第92巻、第11号

村上僚 (Role: Contributor, バイオミディア: 何気にホットな古細菌)

日本生物工学会, 2014

Presentations

Identification and molecular analysis of a novel RNA helicase driving ping-pong cycle

Ryo Murakami

20th Annual Meeting of the RNA Society of Japan, Jul 9, 2018
Newly identified RNA helicase BmDDX43 dissociates cleaved target RNA from Ago3 in silkworm.

Ryo Murakami, Lumi Negishi, Mikiko C. Siomi

Japanese-Russian Symposium on piRNA Silencing and Heterochromatin, Mar 13, 2018
リボソームサブユニット会合における翻訳開始因子IF5Bとリボソームストーク間相互作用の構造・機能基盤

村上僚, 伊東孝祐, Jacob Morris, Leiming Tang, 三好智博, 浅野桂, 内海利男

第38回日本分子生物学会年会・第88回日本生化学会大会合同大会 (BMB2015), Dec, 2015
Structural analysis of the archaeal translation initiation factor 5B in complex with ribosomal stalk protein P1.

Ryo Murakami, Kosuke Ito, Tomohiro Miyoshi, Toshio Uchiumi

The 3rd International Congress on Natural Sciences with Sisterhood Universities (ICNS 2013), Oct, 2013

Professional Memberships

Research Projects

生殖組織特異的RNAヘリカーゼによるPIWIタンパク質の認識メカニズムの解明

科学研究費助成事業, 若手研究, 日本学術振興会, Apr, 2020 - Mar, 2021

村上僚
ピンポンサイクル経路を駆動する新奇RNAヘリカーゼの機能解析

若手研究, 日本学術振興会, Apr, 2018 - Mar, 2020

村上僚
生殖細胞特異的RNAヘリカーゼによるRNA発現制御メカニズムの解明

基礎科学研究助成, 公益財団法人住友財団, Nov, 2018 - Oct, 2019

村上僚
翻訳開始及びリボソーム成熟化におけるIF5B-ストークタンパク質複合体の機能解析

特別研究員奨励費, 日本学術振興会, Apr, 2015 - Mar, 2017

村上僚

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Education

Awards

Papers

Books and Other Publications

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