論文

査読有り 国際誌
2020年

The Accuracy of the Patient Health Questionnaire-9 Algorithm for Screening to Detect Major Depression: An Individual Participant Data Meta-Analysis.

Psychotherapy and psychosomatics
  • Chen He
  • ,
  • Brooke Levis
  • ,
  • Kira E Riehm
  • ,
  • Nazanin Saadat
  • ,
  • Alexander W Levis
  • ,
  • Marleine Azar
  • ,
  • Danielle B Rice
  • ,
  • Ankur Krishnan
  • ,
  • Yin Wu
  • ,
  • Ying Sun
  • ,
  • Mahrukh Imran
  • ,
  • Jill Boruff
  • ,
  • Pim Cuijpers
  • ,
  • Simon Gilbody
  • ,
  • John P A Ioannidis
  • ,
  • Lorie A Kloda
  • ,
  • Dean McMillan
  • ,
  • Scott B Patten
  • ,
  • Ian Shrier
  • ,
  • Roy C Ziegelstein
  • ,
  • Dickens H Akena
  • ,
  • Bruce Arroll
  • ,
  • Liat Ayalon
  • ,
  • Hamid R Baradaran
  • ,
  • Murray Baron
  • ,
  • Anna Beraldi
  • ,
  • Charles H Bombardier
  • ,
  • Peter Butterworth
  • ,
  • Gregory Carter
  • ,
  • Marcos Hortes Nisihara Chagas
  • ,
  • Juliana C N Chan
  • ,
  • Rushina Cholera
  • ,
  • Kerrie Clover
  • ,
  • Yeates Conwell
  • ,
  • Janneke M de Man-van Ginkel
  • ,
  • Jesse R Fann
  • ,
  • Felix H Fischer
  • ,
  • Daniel Fung
  • ,
  • Bizu Gelaye
  • ,
  • Felicity Goodyear-Smith
  • ,
  • Catherine G Greeno
  • ,
  • Brian J Hall
  • ,
  • Patricia A Harrison
  • ,
  • Martin Härter
  • ,
  • Ulrich Hegerl
  • ,
  • Leanne Hides
  • ,
  • Stevan E Hobfoll
  • ,
  • Marie Hudson
  • ,
  • Thomas N Hyphantis
  • ,
  • Masatoshi Inagaki
  • ,
  • Khalida Ismail
  • ,
  • Nathalie Jetté
  • ,
  • Mohammad E Khamseh
  • ,
  • Kim M Kiely
  • ,
  • Yunxin Kwan
  • ,
  • Femke Lamers
  • ,
  • Shen-Ing Liu
  • ,
  • Manote Lotrakul
  • ,
  • Sonia R Loureiro
  • ,
  • Bernd Löwe
  • ,
  • Laura Marsh
  • ,
  • Anthony McGuire
  • ,
  • Sherina Mohd-Sidik
  • ,
  • Tiago N Munhoz
  • ,
  • Kumiko Muramatsu
  • ,
  • Flávia L Osório
  • ,
  • Vikram Patel
  • ,
  • Brian W Pence
  • ,
  • Philippe Persoons
  • ,
  • Angelo Picardi
  • ,
  • Katrin Reuter
  • ,
  • Alasdair G Rooney
  • ,
  • Iná S da Silva Dos Santos
  • ,
  • Juwita Shaaban
  • ,
  • Abbey Sidebottom
  • ,
  • Adam Simning
  • ,
  • Lesley Stafford
  • ,
  • Sharon Sung
  • ,
  • Pei Lin Lynnette Tan
  • ,
  • Alyna Turner
  • ,
  • Henk C P M van Weert
  • ,
  • Jennifer White
  • ,
  • Mary A Whooley
  • ,
  • Kirsty Winkley
  • ,
  • Mitsuhiko Yamada
  • ,
  • Brett D Thombs
  • ,
  • Andrea Benedetti

89
1
開始ページ
25
終了ページ
37
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1159/000502294

BACKGROUND: Screening for major depression with the Patient Health Questionnaire-9 (PHQ-9) can be done using a cutoff or the PHQ-9 diagnostic algorithm. Many primary studies publish results for only one approach, and previous meta-analyses of the algorithm approach included only a subset of primary studies that collected data and could have published results. OBJECTIVE: To use an individual participant data meta-analysis to evaluate the accuracy of two PHQ-9 diagnostic algorithms for detecting major depression and compare accuracy between the algorithms and the standard PHQ-9 cutoff score of ≥10. METHODS: Medline, Medline In-Process and Other Non-Indexed Citations, PsycINFO, Web of Science (January 1, 2000, to February 7, 2015). Eligible studies that classified current major depression status using a validated diagnostic interview. RESULTS: Data were included for 54 of 72 identified eligible studies (n participants = 16,688, n cases = 2,091). Among studies that used a semi-structured interview, pooled sensitivity and specificity (95% confidence interval) were 0.57 (0.49, 0.64) and 0.95 (0.94, 0.97) for the original algorithm and 0.61 (0.54, 0.68) and 0.95 (0.93, 0.96) for a modified algorithm. Algorithm sensitivity was 0.22-0.24 lower compared to fully structured interviews and 0.06-0.07 lower compared to the Mini International Neuropsychiatric Interview. Specificity was similar across reference standards. For PHQ-9 cutoff of ≥10 compared to semi-structured interviews, sensitivity and specificity (95% confidence interval) were 0.88 (0.82-0.92) and 0.86 (0.82-0.88). CONCLUSIONS: The cutoff score approach appears to be a better option than a PHQ-9 algorithm for detecting major depression.

リンク情報
DOI
https://doi.org/10.1159/000502294
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/31593971
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960351

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