Yamamoto Shinichi

Profile Information

Affiliation: Research Collaborator, School of Medicine Department of Microbiology and Immunology, Keio University
: Assistant professor, Center for Immune Therapeutics and Diagnosis, Advanced Research Institute for Health Science, Juntendo University

Degree: Doctor (Engineering)(Soka University)

Researcher number: 10634800
J-GLOBAL ID: 201301005908668084
researchmap Member ID: 7000004244

Research Interests

Research Areas

Education

Apr, 2009 - Mar, 2012

生命情報工学専攻, 工学研究科, Soka University
Apr, 2007 - Mar, 2009

生命情報工学専攻, 工学研究科, Soka University
Apr, 2003 - Mar, 2007

生命情報工学科, 工学部, Soka University

Awards

Papers

In Vitro Generation of Brain Regulatory T Cells by Co-culturing With Astrocytes

Shinichi Yamamoto, Ako Matsui, Masaki Ohyagi, Chie Kikutake, Yoshihiro Harada, Mana Iizuka-Koga, Mikita Suyama, Akihiko Yoshimura, Minako Ito

Frontiers in Immunology, 13 960036-960036, Jul 15, 2022 Peer-reviewed
Targeting mantle cell lymphoma metabolism and survival through simultaneous blockade of mTOR and nuclear transporter exportin-1

Sekihara K, Saitoh K, Han L, Ciurea S, Yamamoto S, Kikkawa M, Kazuno S, Taka H, Kaga N, Arai H …

Oncotarget, 8(21) 34552-34564, May 23, 2017 Peer-reviewed
Bone Marrow Adipocytes Facilitate Fatty Acid Oxidation Activating AMPK and a Transcriptional Network Supporting Survival of Acute Monocytic Leukemia Cells

Tabe Y, Yamamoto S, Saitoh K, Sekihara K, Monma N, Ikeo K, Mogushi K, Shikami M, Ruvolo V, Ishizawa J …

Cancer Research, 77(6) 1453-1464, Mar 15, 2017 Peer-reviewed
Integrative genomic and proteomic analyses identifies glycerol-3-phosphate acyltransferase as a target of low-dose ionizing radiation in EBV infected-B cells

Tabe Y, Hatanaka Y, Nakashiro M, Sekihara K, Yamamoto S, Matsushita H, Kazuno S, Fujimura T, Ikegami T, Nakanaga K …

International Journal of Radiation Bioly, 92(1) 24-34, 2016 Peer-reviewed
The novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor AZD1208 inhibits growth in acute myeloid leukemia via HSF pathway suppression

Harada M, Benito J, Yamamoto S, Kaur S, Arslan D, Ramirez S, Jacamo R, Platanias L, Matsushita H, Fujimura T …

Oncotarget, 6(35) 37930-47, Nov 10, 2015 Peer-reviewed
Ribosomal biogenesis and translational flux inhibition by the selective inhibitor of nuclear export (SINE) XPO1 antagonist KPT-185

Tabe Y, Kojima K, Yamamoto S, Sekihara K, Matsushita H, Davis RE, Wang Z, Ma W, Ishizawa J, Kazuno S …

PLoS One, 10(9) e0137210, Sep 4, 2015 Peer-reviewed
Functional down-regulation of axotomized rat facial motoneurons

Ichimiya T, Yamamoto S, Honda Y, Kikuchi R, Kohsaka S, Nakajima K

Brain Research, 1507 35-44, Apr 24, 2013 Peer-reviewed
Role of cell cycle-associated proteins in microglial proliferation in the axotomized rat facial nucleus

Yamamoto S, Kohsaka S, Nakajima K

Glia, 60(4) 570-581, Apr, 2012 Peer-reviewed
Superoxide anion contributes to the induction of tumor necrosis factor alpha (TNFα) through activation of the MKK3/6-p38 MAPK cascade in rat microglia

Yoshino Y, Yamamoto S, Kohsaka S, Oshiro S, Nakajima K

Brain Research, 1422 1-12, Nov 8, 2011 Peer-reviewed
Macrophage-colony stimulating factor as an inducer of microglial proliferation in axotomized rat facial nucleus

Yamamoto S, Nakajima K, Kohsaka S

Journal of Neurochemistry, 115(4) 1057-1067, Nov, 2010 Peer-reviewed
Close association of p38 and JNK with plasminogen-dependent upregulation of PAI-1 in rat astrocytes in vitro

Nakajima K, Yamamoto S, Tohyama Y, Kohsaka S

471(2) 66-69, Mar 3, 2010 Peer-reviewed
Neuronal stimulation leading to upregulation of glutamate transporter-1 (GLT-1) in rat microglia in vitro

Nakajima K, Yamamoto S, Kohsaka S, Kurihara T

Neuroscience Letters, 436(3) 331-334, May 16, 2008 Peer-reviewed

Misc.

【神経免疫メカニズムと疾患神経系と免疫系を結ぶ分子機構の解明からバイオマーカー・治療標的の探索まで】(第1章)神経免疫のメカニズム神経炎症の誘導と制御(リンパ球) 制御性T細胞による中枢神経炎症制御

伊藤美菜子, 山本伸一, 大谷木正貴, 吉村昭彦

実験医学, 39(15) 2342-2347, Sep, 2021
Regulatory T cells and IL-33

伊藤美菜子, 大谷木正貴, 山本伸一, 吉村昭彦

臨床免疫・アレルギー科, 74(5) 470-476, Nov, 2020
Tissue regulatory T cells and tissue repair

伊藤美菜子, 山本伸一, 吉村昭彦

臨床免疫・アレルギー科, 72(6) 575-582, Dec, 2019

Books and Other Publications

生物の寿命延長 : 老化・長寿命の基盤研究最前線

山本伸一, 大谷木正貴, 安藝大輔, 伊藤美菜子, 吉村昭彦 (Role: Contributor, 免疫老化制御と寿命延長)

エヌ・ティー・エス, Mar, 2022 (ISBN: 9784860437732)
神経免疫 : メカニズムと疾患 : 神経系と免疫系を結ぶ分子機構の解明からバイオマーカー・治療標的の探索まで

伊藤美菜子, 山本伸一, 大谷木正貴, 吉村昭彦 (Role: Contributor, 制御性T細胞による中枢神経炎症制御)

羊土社, Sep, 2021 (ISBN: 9784758103978)

Research Projects

Acquisition mechanism of brain-specific properties for regulatory T cells in central nervous system diseases

科学研究費助成事業, 基盤研究（Ｃ）, 文部科学省・日本学術振興会, Apr, 2021 - Mar, 2024

Shinichi Yamamoto
高齢者脂肪髄中の白血病細胞の脂肪酸代謝-転写メカニズムと代謝制御マーカーの探索

学長特別共同プロジェクト研究費, 順天堂大学, Apr, 2015 - Mar, 2016

山本伸一
ラットの顔面神経傷害時における増殖性ミクログリアの免疫機能解析

研究開発推進, 創価大学, Apr, 2014 - Mar, 2015

山本伸一
神経傷害時におけるミクログリアの免疫機能発現調節に関する研究

学術研究振興資金, 日本私立学校振興・共済事業団, Apr, 2013 - Mar, 2014

山本伸一
Involvement of MAP kinase cascade in M-CSF-triggered microglial proliferation in transected rat facial nucleus

学術国際会議派遣, 創価大学, Apr, 2013 - Mar, 2014

山本伸一
Signaling mechanism by which microglial proliferate by M-CSF upregulated in the transected rat facial nucleus

学術国際会議派遣, 創価大学, Apr, 2012 - Mar, 2013

山本伸一

Profile Information

Research Interests

Research Areas

Education

Awards

Papers

Misc.

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