Kotaro Sugimoto

Profile Information

Affiliation: Associate Professor, Basic Pathology, Fukushima Medical University School of Medicine

Degree: PhD (Medicine)(Sapporo Medical University)
MD(Sapporo Medical University)

Researcher number: 40791009
ORCID ID: https://orcid.org/0000-0002-5299-7610
J-GLOBAL ID: 201601017297586550
researchmap Member ID: B000265053

External link: http://www.fmu.ac.jp/home/p2/index.html

Google Scholar
https://scholar.google.co.jp/citations?user=nj_tuf8AAAAJ&hl=en

Research Gate
https://www.researchgate.net/profile/Kotaro_Sugimoto

PubMed
https://pubmed.ncbi.nlm.nih.gov

福島県立医科大学研究者データベース
https://www.fmu.ac.jp/kenkyu/html/1852_ja.html

Research Interests

Research Areas

Research History

Jul, 2019 - Present

Associate Professor, Department of Pathology, Fukushima Medical University
Aug, 2016 - Jun, 2019

Assistant Professor/Acting Associate Professor, Department of Pathology, Fukushima Medical University
Apr, 2015 - Jul, 2016

Research Fellow in Abroad, JSPS
Apr, 2013 - Jul, 2016

Postdoctoral Scientist, Cardiac Regeneration Lab, Victor Chang Cardiac Research Institute
Apr, 2011 - Mar, 2013

Research Fellow, DC2, JSPS

Education

Apr, 2010 - Mar, 2013

Graduate School of Medicine, Sapporo Medical University
Apr, 2002 - Mar, 2008

School of Medicine, Sapporo Medical University

Major Papers

The Src-Family Kinases SRC and BLK Contribute to the CLDN6-Adhesion Signaling.

Naoki Ichikawa-Tomikawa, Kotaro Sugimoto, Korehito Kashiwagi, Hideki Chiba

Cells, 12(13), Jun 23, 2023 Peer-reviewedInvitedLead author
Aberrant phosphorylation of human LRH1 at serine 510 is predictable of hepatocellular carcinoma recurrence.

Atsushi Nishimagi, Makoto Kobayashi, Kotaro Sugimoto, Yasuhide Kofunato, Naoya Sato, Junichiro Haga, Teruhide Ishigame, Takashi Kimura, Akira Kenjo, Yasuyuki Kobayashi …

Clinical and experimental medicine, Jun 7, 2023 Peer-reviewedCorresponding author
Claudin-4-adhesion signaling drives breast cancer metabolism and progression via liver X receptor β.

Yuko Murakami-Nishimagi, Kotaro Sugimoto, Makoto Kobayashi, Kazunoshin Tachibana, Manabu Kojima, Maiko Okano, Yuko Hashimoto, Shigehira Saji, Tohru Ohtake, Hideki Chiba

Breast cancer research : BCR, 25(1) 41-41, Apr 14, 2023 Peer-reviewedLead authorCorresponding author
Claudin‑9 is a novel prognostic biomarker for endometrial cancer.

Yuta Endo, Kotaro Sugimoto, Makoto Kobayashi, Yasuyuki Kobayashi, Manabu Kojima, Shigenori Furukawa, Shu Soeda, Takafumi Watanabe, Atsuko Y Higashi, Tomohito Higashi …

International journal of oncology, 61(5), Nov, 2022 Peer-reviewedCorresponding author
The claudin-transcription factor signaling pathway.

Kotaro Sugimoto, Hideki Chiba

Tissue barriers, 1908109-1908109, Apr 27, 2021 Peer-reviewedInvitedLead author
Krüppel-like factor 1 is a core cardiomyogenic trigger in zebrafish.

Masahito Ogawa, Fan-Suo Geng, David T Humphreys, Esther Kristianto, Delicia Z Sheng, Subhra P Hui, Yuxi Zhang, Kotaro Sugimoto, Maki Nakayama, Dawei Zheng …

Science (New York, N.Y.), 372(6538) 201-205, Apr 9, 2021 Peer-reviewed
Reduced Claudin-12 Expression Predicts Poor Prognosis in Cervical Cancer.

Abidur Rahman, Makoto Kobayashi, Kotaro Sugimoto, Yuta Endo, Manabu Kojima, Shigenori Furukawa, Takafumi Watanabe, Shu Soeda, Yuko Hashimoto, Keiya Fujimori …

International journal of molecular sciences, 22(7), Apr 6, 2021 Peer-reviewedLead authorCorresponding author
Aberrant Claudin-6-Adhesion Signaling Promotes Endometrial Cancer Progression via Estrogen Receptor α.

Manabu Kojima, Kotaro Sugimoto, Makoto Kobayashi, Naoki Ichikawa-Tomikawa, Korehito Kashiwagi, Takafumi Watanabe, Shu Soeda, Keiya Fujimori, Hideki Chiba

Molecular cancer research : MCR, 19(7) 1208-1220, Mar 16, 2021 Peer-reviewedLead authorCorresponding author
The region-selective regulation of endothelial claudin-5 expression and signaling in brain health and disorders.

Hideki Chiba, Naoki Ichikawa-Tomikawa, Tetsuya Imura, Kotaro Sugimoto

Journal of cellular physiology, 236(10) 7134-7143, Mar 10, 2021 Peer-reviewedLast author
Soluble JAM-C Ectodomain Serves as the Niche for Adipose-Derived Stromal/Stem Cells.

Morio Yamazaki, Kotaro Sugimoto, Yo Mabuchi, Rina Yamashita, Naoki Ichikawa-Tomikawa, Tetsuharu Kaneko, Chihiro Akazawa, Hiroshi Hasegawa, Tetsuya Imura, Hideki Chiba

Biomedicines, 9(3), Mar 10, 2021 Peer-reviewedLead authorCorresponding author
Serotonin/5-HT1A Signaling in the Neurovascular Unit Regulates Endothelial CLDN5 Expression.

Kotaro Sugimoto, Naoki Ichikawa-Tomikawa, Keisuke Nishiura, Yasuto Kunii, Yasuteru Sano, Fumitaka Shimizu, Akiyoshi Kakita, Takashi Kanda, Tetsuya Imura, Hideki Chiba

International journal of molecular sciences, 22(1), Dec 29, 2020 Peer-reviewedInvitedLead author
Prognostic Significance of Aberrant Claudin-6 Expression in Endometrial Cancer.

Manabu Kojima, Kotaro Sugimoto, Mizuko Tanaka, Yuta Endo, Hitomi Kato, Tsuyoshi Honda, Shigenori Furukawa, Hiroshi Nishiyama, Takafumi Watanabe, Shu Soeda …

Cancers, 12(10), Sep 24, 2020 Peer-reviewedLead authorCorresponding author
Cell adhesion signals regulate the nuclear receptor activity.

Sugimoto K, Ichikawa-Tomikawa N, Kashiwagi K, Endo C, Tanaka S, Sawada N, Watabe T, Higashi T, Chiba H

Proc Natl Acad Sci USA, 116(49) 24600-24609, Nov, 2019 Peer-reviewedLead author
Zebrafish Regulatory T Cells Mediate Organ-Specific Regenerative Programs

Subhra P. Hui, Delicia Z. Sheng, Kotaro Sugimoto, Alvaro Gonzalez-Rajal, Shinichi Nakagawa, Daniel Hesselson, Kazu Kikuchi

DEVELOPMENTAL CELL, 43(6) 659-+, Dec, 2017 Peer-reviewed
NAD Deficiency, Congenital Malformations, and Niacin Supplementation

Hongjun Shi, Annabelle Enriquez, Melissa Rapadas, Ella M. M. A. Martin, Roni Wang, Julie Moreau, Chai K. Lim, Justin O. Szot, Eddie Ip, James N. Hughes …

NEW ENGLAND JOURNAL OF MEDICINE, 377(6) 544-552, Aug, 2017 Peer-reviewed
Zebrafish FOXP3 is required for the maintenance of immune tolerance

Kotaro Sugimoto, Subhra P. Hui, Delicia Z. Sheng, Maki Nakayama, Kazu Kikuchi

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 73 156-162, Aug, 2017 Peer-reviewedLead author
Dissection of zebrafish shha function using site-specific targeting with a Cre-dependent genetic switch

Kotaro Sugimoto, Subhra P. Hui, Delicia Z. Sheng, Kazu Kikuchi

eLife, 6, May, 2017 Peer-reviewedLead author
Tight junction protein claudin-4 is modulated via Delta Np63 in human keratinocytes

Terufumi Kubo, Kotaro Sugimoto, Takashi Kojima, Norimasa Sawada, Noriyuki Sato, Shingo Ichimiya

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 455(3-4) 205-211, Dec, 2014 Peer-reviewedCorresponding author
The Tight-Junction Protein Claudin-6 Induces Epithelial Differentiation from Mouse F9 and Embryonic Stem Cells

Kotaro Sugimoto, Naoki Ichikawa-Tomikawa, Seiro Satohisa, Yushi Akashi, Risa Kanai, Tsuyoshi Saito, Norimasa Sawada, Hideki Chiba

PLOS ONE, 8(10) e75106, Oct, 2013 Peer-reviewedLead author
Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca(2+) absorption between enterocytes

Hiroki Fujita, Kotaro Sugimoto, Shuichiro Inatomi, Toshihiro Maeda, Makoto Osanai, Yasushi Uchiyama, Yoko Yamamoto, Takuro Wada, Takashi Kojima, Hiroshi Yokozaki …

MOLECULAR BIOLOGY OF THE CELL, 19(5) 1912-1921, May, 2008 Peer-reviewedLead author