Takeshi Mizuno

Profile Information

Affiliation: 特任助教, 東京大学附属動物医療センター

Degree: 博士（獣医学）(Jun, 2015, 麻布大学)

Researcher number: 50632741
ORCID ID: https://orcid.org/0000-0002-3274-7833
J-GLOBAL ID: 202001002533953254
researchmap Member ID: R000003845

Research Interests

Cardiovascular Surgery

Research Areas

Research History

Jun, 2020 - Present

循環器科, Ve.C. Japan 動物病院グループ
Sep, 2018 - Present

Project Assistant Professor, the University of Tokyo Veterinary Medical Center, Graduate School of Agricultural and Life Sciences
Apr, 2014 - Apr, 2020

JASMINE Veterinary Cardiovascular Medical Center
Apr, 2017 - Aug, 2018

Project Researcher, the University of Tokyo Veterinary Medical Center, Graduate School of Agricultural and Life Sciences
Apr, 2012 - Mar, 2015

Project Resercher, Department of Biomedical Engineering, National Cerebral and Cardiovascular Center, Research Institute
Apr, 2003 - Mar, 2012

株式会社ACプラザ苅谷動物病院

Education

Apr, 1997 - Mar, 2003

Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology

Committee Memberships

Oct, 2018 - Present

幹事, 日本獣医再生医療学会
Jun, 2013 - Jun, 2014

評議員, 日本獣医循環器学会

Awards

Papers

Case Report: Tricuspid Annuloplasty for Right-Sided Congestive Heart Failure Secondary to Pulmonary Hypertension in a Dog

Takeshi Mizuno, Kenta Sasaki, Sayaka Suzuki, Itsuma Nagao, Noriko Isayama

Frontiers in Veterinary Science, 9, Feb 22, 2022 Peer-reviewedLead authorCorresponding author
Application of Biosheets as Right Ventricular Outflow Tract Repair Materials in a Rat Model.

Takeshi Mizuno, Ryosuke Iwai, Takeshi Moriwaki, Yasuhide Nakayama

Frontiers in veterinary science, 9 837319-837319, 2022 Peer-reviewedLead authorCorresponding author
Analysis of mitral valve morphology in dogs undergoing mitral valve repair with three-dimensional transesophageal echocardiography.

T Mizuno, A Chen, K Mamada, A Takahashi, S Uchida, M Uechi

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 34 64-72, Jan 19, 2021 Peer-reviewedLead authorCorresponding author
Surgical correction for sinus venosus atrial septal defect with partial anomalous pulmonary venous connection in a dog.

T Mizuno, M Mizuno, K Harada, H Takano, A Shinoda, A Takahashi, K Mamada, K Takamura, A Chen, K Iwanaga …

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 28 23-30, Feb 11, 2020 Peer-reviewedLead author
Efficacy of pimobendan on survival and reoccurrence of pulmonary edema in canine congestive heart failure.

Masashi Mizuno, Shigeki Yamano, Shuichi Chimura, Atsushi Hirakawa, Yoshimi Takusagawa, Tamotsu Sawada, Shigeki Maetani, Arane Takahashi, Takeshi Mizuno, Kayoko Harada …

The Journal of veterinary medical science, 79(1) 29-34, Jan 20, 2017 Peer-reviewed
In-body tissue-engineered collagenous connective tissue membranes (BIOSHEETs) for potential corneal stromal substitution.

Naoaki Takiyama, Takeshi Mizuno, Ryosuke Iwai, Masami Uechi, Yasuhide Nakayama

Journal of tissue engineering and regenerative medicine, 10(10) E518-E526, Oct, 2016 Peer-reviewed
Pathologic Manifestations on Surgical Biopsy and Their Correlation with Clinical Indices in Dogs with Degenerative Mitral Valve Disease

J. Lee, M. Mizuno, T. Mizuno, K. Harada, M. Uechi

JOURNAL OF VETERINARY INTERNAL MEDICINE, 29(5) 1313-1321, Sep, 2015 Peer-reviewed
Plasma cytokine levels in dogs undergoing cardiopulmonary bypass.

Takeshi Mizuno, Hiroshi Kamiyama, Masashi Mizuno, Takahiro Mizukoshi, Asako Shinoda, Kayoko Harada, Shuhei Uchida, Joon-seok Lee, Arane Kasuya, Tamotsu Sawada …

Research in veterinary science, 101 99-105, Aug, 2015 Peer-reviewedLead author
Implantation study of a tissue-engineered self-expanding aortic stent graft (bio stent graft) in a beagle model.

Hidetake Kawajiri, Takeshi Mizuno, Takeshi Moriwaki, Ryosuke Iwai, Hatsue Ishibashi-Ueda, Masashi Yamanami, Keiichi Kanda, Hitoshi Yaku, Yasuhide Nakayama

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 18(1) 48-54, Mar, 2015 Peer-reviewed
Successful implantation of autologous valved conduits with self-expanding stent (stent-biovalve) within the pulmonary artery in beagle dogs.

Marina Funayama, Yuichi Matsui, Tsutomu Tajikawa, Taiki Sasagawa, Yuta Saito, Shoko Sagishima, Takeshi Mizuno, Masashi Mizuno, Kayoko Harada, Shuhei Uchida …

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 17(1) 54-61, Mar, 2015 Peer-reviewed
Development of tissue-engineered self-expandable aortic stent grafts (Bio stent grafts) using in-body tissue architecture technology in beagles.

Hidetake Kawajiri, Takeshi Mizuno, Takeshi Moriwaki, Hatsue Ishibashi-Ueda, Masashi Yamanami, Keiichi Kanda, Hitoshi Yaku, Yasuhide Nakayama

Journal of biomedical materials research. Part B, Applied biomaterials, 103(2) 381-6, Feb, 2015 Peer-reviewed
Preparation of an autologous heart valve with a stent (stent-biovalve) using the stent eversion method.

Takeshi Mizuno, Yoshiaki Takewa, Hirohito Sumikura, Kentaro Ohnuma, Takeshi Moriwaki, Masashi Yamanami, Tomonori Oie, Eisuke Tatsumi, Masami Uechi, Yasuhide Nakayama

Journal of biomedical materials research. Part B, Applied biomaterials, 102(5) 1038-45, Jul, 2014 Peer-reviewedLead author
Plasma atrial natriuretic peptide is an early diagnosis and disease severity marker of myxomatous mitral valve disease in dogs.

Takashi Ebisawa, Yuzuru Ohta, Marina Funayama, Shigeki Yamano, Masashi Mizuno, Takeshi Mizuno, Arane Kasuya, Tamotsu Sawada, Junseok Lee, Takahiro Mizukoshi …

Research in veterinary science, 94(3) 717-21, Jun, 2013 Peer-reviewed
Long-term outcome in dogs undergoing mitral valve repair with suture annuloplasty and chordae tendinae replacement.

T Mizuno, T Mizukoshi, M Uechi

The Journal of small animal practice, 54(2) 104-7, Feb, 2013 Peer-reviewedLead author
In Vitro and in vivo Performance of a Completely Autologous Aortic Valved Conduit (BIOVALVE Type VII) Prepared by in Body Tissue Architecture Technology Using a Novel Separable Mold

Yasuhide Nakayama, Yoshiaki Takewa, Hirohito Sumikura, Yuichi Matsui, Masashi Yamanami, Yuichiro Kishimoto, Mamoru Arakawa, Kentaro Omuma, Takeshi Mizuno, Tomonori Oie …

CIRCULATION, 126(21), Nov, 2012 Peer-reviewed
Mitral valve repair under cardiopulmonary bypass in small-breed dogs: 48 cases (2006-2009).

Masami Uechi, Takahiro Mizukoshi, Takeshi Mizuno, Masashi Mizuno, Kayoko Harada, Takashi Ebisawa, Junichirou Takeuchi, Tamotsu Sawada, Shuhei Uchida, Asako Shinoda …

Journal of the American Veterinary Medical Association, 240(10) 1194-201, May 15, 2012 Peer-reviewed
Post-mortem evaluation of expanded polytetrafluoroethylene (ePTFE) used in mitral valve repair in dogs.

Miki Nishida, Yumiko Kagawa, Takahiro Mizukoshi, Masashi Mizuno, Takeshi Mizuno, Kayoko Harada, Masami Uechi

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 14(1) 307-12, Mar, 2012 Peer-reviewed
Surgical treatment of severe pulmonic stenosis under cardiopulmonary bypass in small dogs.

M Fujiwara, K Harada, T Mizuno, M Nishida, T Mizukoshi, M Mizuno, M Uechi

The Journal of small animal practice, 53(2) 89-94, Feb, 2012 Peer-reviewed
Transcatheter Implantation of Autologous in vivo Tissue-Engineered, Valved Stents (BIOVALVED STENTs) in the Pulmonary Position in a Beagle Model

Masami Uechi, Marina Funayama, Yuichi Matsui, Takeshi Mizuno, Megumi Fujiwara, Tsutomu Tajikawa, Kenkichi Ohba, Masashi Yamanami, Taiji Watanabe, Keiichi Kanda …

CIRCULATION, 124(21), Nov, 2011 Peer-reviewed
Surgical closure of an atrial septal defect using cardiopulmonary bypass in a cat.

Masami Uechi, Kayoko Harada, Takahiro Mizukoshi, Takeshi Mizuno, Masashi Mizuno, Takashi Ebisawa, Yuzuru Ohta

Veterinary surgery : VS, 40(4) 413-7, Jun, 2011 Peer-reviewed

Misc.

101

急性呼吸不全に対して膜型人工肺(ECMO)が有効であった犬の一例

諌山紀子, 内村祐介, 佐々木健太, 高橋利尚, 前田英里香, 渡邉めぐみ, 濱本裕仁, 水野壮司, 水野壮司, 鈴木さやか

日本獣医麻酔外科学会オンライン学術集会抄録集(Web), 103rd, 2022
心タンポナーデに立ち向かう特発性心膜炎

水野壮司, 水野壮司

月刊CAP, (391), 2022
まずはここから循環器疾患の標準知識犬の僧帽弁閉鎖不全症

水野壮司

CLINICNOTE, 187(2), Feb, 2021 Invited
犬・猫の全身性高血圧-高血圧の「標的臓器障害」を知る-総論全身性高血圧の概要

水野壮司, 水野壮司

Clinic Note, 17(7), 2021
肺高血圧症に伴う二次性三尖弁閉鎖不全症に対して体外循環下三尖弁輪形成術を実施した犬の1例

佐々木健太, 諌山紀子, 鈴木さやか, 前田英里香, 内村祐介, 長尾乙磨, 水野壮司, 水野壮司

日本獣医循環器学会抄録, 114th (CD-ROM), 2021
症例報告ドキソルビシン投与により、心毒性が認められた症例 (特集これだけは押さえておきたい抗がん薬治療による有害事象への対応(前編))

水野壮司

Veterinary board : 臨床の選択肢を広げるケーススタディ・マガジン, 2(3) 46-54, Mar, 2020
静脈洞型心房中隔欠損症に対して体外循環下修復術を実施した犬の6例

水野壮司, 水野祐, 原田佳代子, 高野裕史, 篠田麻子, 高橋新音, 侭田和也, 陳郁佳, 高村一樹, 新居康行 …

日本獣医麻酔外科学雑誌(Web), 50(Supplement 2), 2019
心筋症に伴う血栓塞栓症による消化管壊死が疑われた猫1例

石川恭平, 中川泰輔, 水野壮司, 水野壮司, 山本貴恵, 木之下怜平, 長久保大, 坪井誠也, チェンバーズジェームズ, 内田和幸 …

日本獣医麻酔外科学雑誌(Web), 50(Supplement 1), 2019
循環器科の診療室(第12回)心膜液貯留

水野壮司

Clinic note : journal of clinical daily treatment for small animals, 14(8) 78-91, Aug, 2018
僧帽弁修復術を実施した犬の8例

多田裕治, 水野壮司, 長谷川寛, 吉政甫, 片山遼平, 水野拓, 高野裕史, 侭田和也, 作野幸孝, 上地正実

動物臨床医学会年次大会プロシーディング, 39th(2), 2018
犬の僧帽弁修復術における心筋保護液の比較検討

侭田和也, 水野祐, 水野壮司, 原田佳代子, 高野裕史, 高橋新音, 篠田麻子, 陳郁佳, 竹内さやか, 上地正実

日本獣医学会学術集会講演要旨集, 161st, 2018
JASMINEどうぶつ循環器病センターにおける犬の僧帽弁修復術の近況報告

水野祐, 陳郁佳, 高村一樹, 水野壮司, 原田佳代子, 高野裕史, 高橋新音, 篠田麻子, 侭田和也, 竹内さやか …

日本獣医麻酔外科学雑誌, 49(Supplement 1), 2018
Influence of persistent left cranial vena cava on mitral valve repair in two dogs

Mizukoshi Takahiro, Uechi Masami, Mizuno Takeshi, Mizuno Masashi, Harada Kayoko, Sawada Tamotsu, Takeuchi Junichiro, Uchida Shuhei, Takahashi Arane, Shinoda Asako

Journal of Veterinary Cardiovascular Medicine, 2(2) 18-24, 2018
Surgical debulking of a right atrial mass using cardiopulmonary bypass in a dog

Mamada Kazuya, Mizuno Takeshi, Mizuno Masashi, Harada Kayoko, Takano Hiroshi, Takahashi Arane, Shinoda Asako, Chen Ayaka, Uechi Masami

Journal of Veterinary Cardiovascular Medicine, 2(1) 6-12, 2018
JASMINEどうぶつ循環器病センターの取り組み (特集僧帽弁閉鎖不全症の治療 : 気になるあの病院の取り組み(後編))

水野壮司

Veterinary circulation : 小動物循環器科専門誌, 6(3) 46-56, Aug, 2017
犬の開心術後に認められる横隔神経麻痺に関する回顧的調査

侭田和也, 水野祐, 水野壮司, 原田佳代子, 高野裕史, 高橋新音, 篠田麻子, 陳郁佳, 高村一樹, 竹内さやか …

関東・東京合同地区獣医師大会・獣医学術関東・東京合同地区学会, 2017, 2017
Management of acute renal failure in a cat using peritoneal dialysis

Harada Kayoko, Mizuno Takeshi, Mamada Kazuya, Uechi Masami

Journal of Veterinary Cardiovascular Medicine, 1(2) 25-30, 2017
Right heart failure secondary to cardiac chondrosarcoma in a dog

Mamada Kazuya, Mizuno Takeshi, Kagawa Yumiko, Uechi Masami

Journal of Veterinary Cardiovascular Medicine, 1(1) 15-19, 2017
心原性チアノーゼ (特集チアノーゼ : 原因をすばやく見極めて適確な救命を)

水野壮司

Veterinary circulation : 小動物循環器科専門誌, 5(3) 18-27, Aug, 2016
循環器科の診療室 : Case Study(第6回)心拡大

水野壮司

Clinic note : journal of clinical daily treatment for small animals, 12(5) 66-79, May, 2016

Books and Other Publications

伴侶動物治療指針 : 臓器・疾患別最新の治療法33

石田, 卓夫, 水野壮司 (Role: Contributor, 心疾患治療における心臓バイオマーカーの活用)

チクサン出版社,緑書房 (発売), 2013 (ISBN: 9784885006753)
猫の血栓塞栓症に対するtissue-Plasminogen activator (t-PA)製剤による血栓溶解療法

水野壮司

動物の循環器（日本獣医循環器学会発行）, 2012
液状フィブリン製剤の紹介

水野壮司, 上地正実

Surgeon Vol. 74（インターズー）, Mar, 2009

Presentations

ベーシック技術講座：刺して採る技術心膜穿刺

水野壮司

日本獣医内科学アカデミー学術集会, Feb 22, 2020 Invited
MRの診断と治療 -ACVIM consensus guideline 2019-

水野壮司

VMCセミナー, Sep 20, 2019
MRの治療時に迷う利尿剤のアートな部分

水野壮司

まちだ小動物クリニカルカンファレンス, Jun 30, 2019 Invited
これって肺高血圧症？

水野壮司

まちだ小動物クリニカルカンファレンス, Jun 30, 2019 Invited
猫の心疾患の救急治療

水野壮司

六青会, Mar 7, 2019
古くて新しいフィラリア治療（薬物療法？虫体摘出？）

水野壮司

日本獣医内科学アカデミー学術集会, Feb 15, 2019 Invited
僧帽弁閉鎖不全症に対する外科治療と内科治療

水野壮司

静岡県獣医師会学術セミナー, Nov 3, 2018 Invited
救急医療の最前線〜専門医と生討論〜循環器科

水野壮司

日本動物病院協会年次大会, Oct 28, 2018 Invited
見直そう尿検査

水野壮司

第２回動物循環器病学会学術集会, Sep 30, 2017
心電図の読み方

水野壮司

第１回動物循環器病学会学術集会, Mar 11, 2017
僧帽弁閉鎖不全症に対する開心術の現状手術適応症例の見極め

水野壮司

日本獣医内科学アカデミー学術集会, Feb 18, 2017
獣医心臓外科のいま

水野壮司

埼玉動物医療センター獣医師向けセミナー, Apr 20, 2016
生体内組織形成技術による心臓人工弁

水野壮司

第 7 回動物用ワクチン─バイオ医薬品研究会シンポジウム, Sep 9, 2015 Invited
重度僧帽弁閉鎖不全症における心房細動が僧帽弁形成術後に消失した犬の2例

藤原めぐみ, 上地正実, 水越崇博, 海老澤崇史, 水野祐, 水野壮司, 原田佳代子, 西田幹, 鯉江洋, 坂井学, 滝山直昭

獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, Dec 20, 2008
心房静止を診断するにあたりANP血中濃度測定が有用であった猫の3例

豊福健, 岩永孝治, 水野壮司, 原口純子, 伊藤裕行, 大倉真紀子, 溝口期子, 内田恵子, 苅谷和廣

獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, Nov 20, 2007
心タンポナーデと左室収縮機能低下が認められた犬の1例

岩永孝治, 水野壮司, 豊福建, 原口純子, 内田恵子, 苅谷和廣

獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, Nov 20, 2007
重度僧帽弁閉鎖不全症に対して僧帽弁形成術を行い2年余り経過した犬の3例

水野壮司, 上地正実, 岩永孝治, 豊福建, 森重純子, 海老澤崇史, 水越隆博, 南毅生, 内田恵子, 苅谷和廣

獣医麻酔外科学雑誌 = Japanese journal of veterinary anesthesia & surgery, Nov 20, 2007
左室2腔症の猫の一例

水野壮司, 岩永孝治, 内田恵子, 苅谷和廣

日本獣医循環器学会抄録, Jun 25, 2005
一過性の求心性心肥大を認め急性心筋炎を疑った犬の一例

岩永孝治, 酒井康二, 豊福健, 水野壮司, 内田恵子, 苅谷和廣

日本獣医循環器学会抄録, Jun 25, 2005
腱索断裂による重度僧帽弁閉鎖不全症の小型犬に僧房弁形成術を施行した一例

岩永孝治, 上地正実, 堀泰智, 水野壮司, 海老澤崇史, 水越隆博, 篠田麻子, 豊福健, 内田恵子, 苅谷和廣, 南毅生, 安部瑞江, 大幡真奈美, 小笠原茂里人, 赤穂芳彦

日本獣医循環器学会抄録, Jun 25, 2005

Teaching Experience

基礎臨床学実習I (東京大学)

Professional Memberships

Research Projects

Development of the novel valved stent composed of completely autologous tissue from Japan.

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2015

MIZUNO Takeshi, YAMANAMI Masashi, NAKAYAMA Yasuhide, IWAI Ryosuke, MORIWAKI Takeshi

Profile Information

Research Interests

Research Areas

Research History

Education

Committee Memberships

Awards

Papers

Misc.

Books and Other Publications

Presentations

Teaching Experience

Professional Memberships

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