2013
Detection of DNA induced gold nanoparticle aggregation with dark field imaging
CHEMICAL COMMUNICATIONS
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- ,
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- Volume
- 49
- Number
- 68
- First page
- 7531
- Last page
- 7533
- Language
- English
- Publishing type
- Research paper (scientific journal)
- DOI
- 10.1039/c3cc44182b
- Publisher
- ROYAL SOC CHEMISTRY
Dark field imaging was employed to visualize and quantify complementary DNA-induced gold nanoparticle aggregation at the single-particle level, with a detection limit of 100 fM DNA, which allows the highly sensitive detection of single nucleotide polymorphisms (SNPs). Results suggested that the aggregation process is consistent with the cluster-cluster model.
- Link information
- ID information
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- DOI : 10.1039/c3cc44182b
- ISSN : 1359-7345
- Pubmed ID : 23863889
- Web of Science ID : WOS:000322451100020