2017
Significance of High-frequency Electrical Brain Activity
ACTA MEDICA OKAYAMA
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- Volume
- 71
- Number
- 3
- First page
- 191
- Last page
- 200
- Language
- English
- Publishing type
- DOI
- 10.18926/AMO/55201
- Publisher
- OKAYAMA UNIV MED SCHOOL
Electroencephalogram (EEG) data include broadband electrical brain activity ranging from infra-slow bands (<0.1 Hz) to traditional frequency bands (e.g., the approx. 10 Hz alpha rhythm) to high-frequency bands of up to 500 Hz. High-frequency oscillations (HFOs) including ripple and fast ripple oscillations (80-200 Hz and >200/250 Hz, respectively) are particularly of note due to their very close relationship to epileptogenicity, with the possibility that they could function as a surrogate biomarker of epileptogenicity. In contrast, physiological high-frequency activity plays an important role in higher brain functions, and the differentiation between pathological/epileptic and physiological HFOs is a critical issue, especially in epilepsy surgery. HFOs were initially recorded with intracranial electrodes in patients with intractable epilepsy as part of a long-term invasive seizure monitoring study. However, fast oscillations (FOs) in the ripple and gamma bands (40-80 Hz) are now noninvasively detected by scalp EEG and magnetoencephalography, and thus the scope of studies on HFOs/FOs is rapidly expanding.
- Link information
- ID information
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- DOI : 10.18926/AMO/55201
- ISSN : 0386-300X
- Pubmed ID : 28655938
- Web of Science ID : WOS:000406105600001