2006年10月
Localization of Vanabins, vanadium-binding proteins, in the blood cells of the vanadium-rich ascidian, Ascidia sydneiensis samea
ZOOLOGICAL SCIENCE
- ,
- ,
- ,
- ,
- 巻
- 23
- 号
- 10
- 開始ページ
- 909
- 終了ページ
- 915
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.2108/zsj.23.909
- 出版者・発行元
- ZOOLOGICAL SOC JAPAN
Some species of the family Ascidiidae accumulate vanadium in concentrations in excess of 350 mM, which is about 10(7)-fold higher than the concentration of vanadium in seawater. In these species, signet ring cells with a single large vacuole in which vanadium ions are contained function as vanadium-accumulating cells. These have been termed vanadocytes. We recently isolated five vanadium-binding proteins, which we named Vanabin1, Vanabin2, Vanabin3, Vanabin4, and VanabinP, from vanadocytes of the vanadium-rich ascidian Ascidia sydneiensis samea. In this study, we analyzed localization of the Vanabins in the blood cells of A. sydneiensis samea using monoclonal antibodies and confocal microscopy. The Vanabin1 and Vanabin2 proteins were found in the cytoplasm and/or in some organelles of vanadocytes. Vanabin3 was also detected in the cytoplasm, while Vanabin4 was found exclusively in the cytoplasmic membrane.
- リンク情報
- ID情報
-
- DOI : 10.2108/zsj.23.909
- ISSN : 0289-0003
- PubMed ID : 17116994
- Web of Science ID : WOS:000243557000009