2003年
Observation and analysis of single DNA nano-kinetics by pin-fiber video scope
ANALYST
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- 巻
- 128
- 号
- 6
- 開始ページ
- 676
- 終了ページ
- 680
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/b212830f
- 出版者・発行元
- ROYAL SOC CHEMISTRY
The nano-kinetic movement of a single DNA molecule was observed and analyzed by a newly developed video-microscope system with an optical fiber, called a pin-fiber video scope. A single lambda-DNA molecule was put in focus using fiber-illumination, and the stretching and shrinking motion was measured. The molecule's kinetics were analyzed by numerical calculations and are discussed. A photocleavage phenomenon of DNA molecules was also visualized by the pin-fiber video scope. The new video-microscope system has the potential to observe and analyze the nano-kinetics of a single molecule.
- リンク情報
- ID情報
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- DOI : 10.1039/b212830f
- ISSN : 0003-2654
- PubMed ID : 12866887
- Web of Science ID : WOS:000183407400029