2014年6月
Galactosylation of human erythropoietin produced by chimeric chickens expressing galactosyltransferase.
Journal of bioscience and bioengineering
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- 巻
- 117
- 号
- 6
- 開始ページ
- 676
- 終了ページ
- 9
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/j.jbiosc.2013.11.010
Human erythropoietin produced in the egg white of chimeric chicken contains N-glycan with lower amounts of terminal galactose and sialic acid; therefore, the chicken galactosyltransferase gene was introduced together with the human erythropoietin gene by a retroviral vector. We found that erythropoietin accumulated in the egg white was partially galactosylated.
- リンク情報
- ID情報
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- DOI : 10.1016/j.jbiosc.2013.11.010
- PubMed ID : 24355574