ASANO Naoki

J-GLOBAL         Last updated: Nov 30, 2018 at 14:34
 
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Name
ASANO Naoki
URL
http://db.tohoku.ac.jp/whois/e_detail/c838573d69900307568f1db4a02a1daa.html
Affiliation
Tohoku University
Section
Graduate School of Medicine Department of Medical Sciences
Job title
Assistant Professor
Degree
Revelation of homeobox gene Cdx2 in gastric mucosa by Helicobacter pylori infection(Tohoku University)

Research Areas

 
 

Academic & Professional Experience

 
Jun 2018
 - 
Today
Lecturer, Division of Gastroenterology, Tohoku UniversityGraduate School of Medicine
 
Sep 2010
 - 
May 2018
Assistant Professor, Department of Gastroenterology, Tohoku University Hospital
 
Apr 2010
 - 
Aug 2010
内科医師, 国立療養所東北新生園
 
Jul 2008
 - 
Mar 2010
医員, 東北大学病院 消化器内科
 
Jul 2005
 - 
Jun 2008
Research fellow, Mucosal Immunity Section, Lab of Host Defenses, NIAID, NIH
 

Education

 
 
 - 
Mar 2004
Graduate School, Division of Medicine, Tohoku University
 
 
 - 
Mar 1997
Faculty of Medicine, Tohoku University
 

Awards & Honors

 
Jun 2017
自然免疫応答の破綻による胃発癌機構の解明, 第28回黒川利雄がん研究基金, 宮城県対がん協会
 
Aug 2005
H.pylori刺激によるNFκBを介した腸上皮化生関連遺伝子Cdx2の発現調節機構, 第12回消化管分子機構研究会優秀演題, 消化管分子機構研究会
 
May 2004
Helicobacter pylori infection induces intestinal metaplasia related gene Cdx2 in gastric epithelial cells via PTEN-PI3K/Akt-NF-kappaB pathway, Poster of distinction
 

Published Papers

 
Kondo Y, Hatta W, Koike T, Takahashi Y, Saito M, Kanno T, Asanuma K, Asano N, Imatani A, Masamune A
Digestive diseases and sciences      Jul 2018   [Refereed]
Murata T, Asanuma K, Ara N, Iijima K, Hatta W, Hamada S, Asano N, Koike T, Imatani A, Masamune A, Shimosegawa T
The Tohoku journal of experimental medicine   245(1) 45-53   May 2018   [Refereed]
Minaga K, Watanabe T, Kamata K, Asano N, Kudo M
World journal of gastroenterology   24(16) 1725-1733   Apr 2018   [Refereed]
Okata H, Hatta W, Iijima K, Asanuma K, Tsuruya A, Asano N, Koike T, Hamada S, Nakayama T, Masamune A, Shimosegawa T
The Tohoku journal of experimental medicine   244(4) 317-325   Apr 2018   [Refereed]
Takahashi Y, Uno K, Iijima K, Abe Y, Koike T, Asano N, Asanuma K, Shimosegawa T
Oncotarget   9(26) 18069-18083   Apr 2018   [Refereed]
Estrogen-dependent Nrf2 expression protects against reflux-induced esophagitis
Torihata Y, Asanuma K, Iijima K, Mikami T, Hamada S, Asano N, Koike T, Imatani A, Masamune A, Shimosegawa T
Digestive Disease and Sciences      Dec 2017   [Refereed]
Watanabe T, Asano N, Kudo M, Strober W
The Proceedings of the Japan Academy, Series B   93(8) 578-599   Oct 2017   [Refereed]
Takahashi K, Hatta W, Koike T, Kanno T, Ara N, Asanuma K, Asano N, Imatani A, Fujishima F, Sasano H, Shimosegawa T
Clinical Journal of Gastroenterology      Jun 2017   [Refereed]
Hatta W, Koike T, Iijima K, Asanuma K, Asano N, Musha H, Inomata Y, Sano T, Endo H, Ikehata A, Horii T, Ohyauchi M, Yokosawa S, Kasajima A, Fujishima F, Sasano H, Nakaya N, Nakamura T, Shimosegawa T
Digestion   95(3) 201-209   Mar 2017   [Refereed]
Ami R, Hatta W, Iijima K, Koike T, Ohkata H, Kondo Y, Ara N, Asanuma K, Asano N, Imatani A, Shimosegawa T
Clinical Gastroenterology      Aug 2016   [Refereed]
Konishi H, Asano N, Imatani A, Kimura O, Kondo Y, Jin X, Kanno T, Hatta W, Ara N, Asanuma K, Koike T, Shimosegawa T
Oncotarget      Jul 2016   [Refereed]
Hatta W, Uno K, Koike T, Ara N, Asano N, Iijima K, Imatani A, Fujishima F, Shimosegawa T
Digestive Endoscopy   28(4) 427-433   May 2016   [Refereed]
Maejima R, Uno K, Iijima K, Fujishima F, Noguchi T, Ara N, Asano N, Koike T, Imatani A, Shimosegawa T
Digestive Endoscopy   28(4) 476-480   May 2016   [Refereed]
Honda J, Iijima K, Asanuma K, Ara N, Shiroki T, Kondo Y, Hatta W, Uno K, Asano N, Koike T, Shimosegawa T
Digestive Disease Science   61(4) 1028-1038   Apr 2016   [Refereed]
Asano N, Imatani A, Watanabe T, Fushiya J, Kondo Y, Jin X, Ara N, Uno K, Iijima K, Koike T, Strober W, Shimosegawa T
Cancer Research   76(5) 1135-1145   Mar 2016   [Refereed]
Nakagawa K, Koike T, Iijima K, Saito M, Kikuchi H, Hatta W, Ara N, Uno K, Asano N, Shimosegawa T
World Journal of Gastroenterology   21(47) 13352-13359   Dec 2015   [Refereed]
Asano N, Iijima K, Koike T, Imatani A, Shimosegawa T
World Journal of Gastroenterology   21(26) 8014-8020   Jul 2015   [Refereed][Invited]
Hatta W, Iijima K, Koike T, Kondo Y, Ara N, Asanuma K, Uno K, Asano N, Imatani A, Shimosegawa T.
Digestive Endoscopy      Dec 2014   [Refereed]
Watanabe T*, Asano N*, Meng G, Yamashita K, Arai Y, Sakurai T, Kudo M, Fuss IJ, Kitani A, Shimosegawa T, Chiba T, Strober W
Mucosal Immunology   7(6) 1312-1315   Nov 2014   [Refereed]
Ara N, Iijima K, Maejima R, Kondo Y, Kusaka G, Hatta W, Uno K, Asano N, Koike T, Imatani A, Shimosegawa T.
Digestive Endoscopy      Nov 2014   [Refereed]
Strober W, Asano N, Fuss I, Kitani A, Watanabe T
Immunological Reviews   260(1) 249-260   Jul 2014   [Refereed][Invited]
Iijima K, Koike T, Ara N, Nakagawa K, Kondo Y, Uno K, Hatta W, Asano N, Imatani A, Shimosegawa T
Journal of Gastroenterology      Jun 2014   [Refereed]
Shinkai H, Iijima K, Koike T, Nakagawa K, Maejima R, Endo H, Ara N, Asano N, Imatani A, Ohara S, Shimosegawa T
Tohoku Journal of Experimental Medicine   232(4) 255-261   Apr 2014   [Refereed]
Nakagawa kenichiro, Koike Tomoyuki, Iijima Katsunori, Shinkai Hirohiko, Hatta Waku, Endo Hiroyuki, Ara Nobuyuki, Uno Kaname, Asano Naoki, Imatani Akira, Shimosegawa Tooru
American Journal of Gastroenterology   109(3) 348-356   Mar 2014   [Refereed]
Jin Xiaoyi, Koike Tomoyuki, Chiba Takashi, Kondo Yutaka, Ara Nobuyuki, Uno Kaname, Asano Naoki, Iijima Katsunori, Imatani Akira, Watanabe Mika, Shirane Akio, Shimosegawa Tooru
Digestive Endoscopy   25(5) 547-549   Sep 2013   [Refereed]
Ara Nobuyuki, Uno Kaname, Iijima Katsunori, Koike Tomoyuki, Asano Naoki, Shimosegawa Tooru
Endoscopy   45(4) 313-315   Apr 2013   [Refereed]
Iwai W, Abe Y, Iijima K, Koike T, Uno K, Asano N, Imatani A, Shimosegawa T.
Journal of Gastroenterology      Feb 2013   [Refereed]
Masaka T, Iijima K, Endo H, Asanuma K, Ara N, Ishiyama F, Asano N, Koike T, Imatani A, Shimosegawa T
Gut      Jan 2013   [Refereed]
Iijima K, Ara N, Abe Y, Koike T, Iwabuchi T, Shinkai H, Uno K, Endo H, Asano N, Shimosegawa T
Journal of Gastroenterology      Dec 2012   [Refereed]
Oikawa Tomoyuki, Asano Naoki, Imatani Akira, Ohyauchi Motoki, Fushiya Jun, Kondo Yutaka, Abe Yasuhiko, Koike Tomoyuki, Iijima Katsunori, Shimosegawa Tooru
Hum Immunol   73(11) 1184-1189   Nov 2012   [Refereed]
Kusaka Gen, Uno Kaname, Iijima Katsunori, Endo Hiroyuki, Asano Naoki, Koike Tomoyuki, Imatani Akira, Shimosegawa Tooru
Scand J Gastroenterol   47(10) 1148-1158   Oct 2012   [Refereed]
Uno Kaname, Iijima Katsunori, Koike Tomoyuki, Abe Yatsuhiko, Asano Naoki, Ara Nobuyuki, Shimosegawa Tooru
J Clin Gastroenterol   46(9) e76-82   Oct 2012   [Refereed]
Hatta Waku, Uno Kaname, Koike Tomoyuki, Iijima Katsunori, Asano Naoki, Imatani Akira, Shimosegawa Tooru
Gastrointest Endosc   76(3) 548-555   Sep 2012   [Refereed]
Uno Kaname, Iijima Katsunori, Koike Tomoyuki, Abe Yasuhiko, Asano Naoki, Yokosawa Satoshi, Imatani Akira, Shimosegawa Tooru
Surg Laparosc Endosc Percutan Tech   22(4) e226-9   Aug 2012   [Refereed]
Iijima Katsunori, Abe Yasuhiko, Koike Tomoyuki, Uno Kaname, Endo Hiroyuki, Hatta Waku, Asano Naoki, Asanuma Kiyotaka, Imatani Akira, Shimosegawa Tooru
Tohoku J Exp Med   226(1) 45-53   Apr 2012   [Refereed]
Asano Naoki, Iijima Katsunori, Terai Shiho, Jin Xiaoyi, Ara Nobuyuki, Chiba Takashi, Fushiya Jun, Koike Tomoyuki, Imatani Akira, Shimosegawa Tooru
Tohoku J Exp Med   228(3) 223-227   Apr 2012   [Refereed]
Chiba Takashi, Iijima Katsunori, Koike Tomoyuki, Uno Kaname, Asano Naoki, Shimosegawa Tooru
Case Rep Gastroenterol   6(1) 103-110   Jan 2012   [Refereed]
Uno Kaname, Kato Katsuaki, Kusaka Gen, Asano Naoki, Iijima Katsunori, Shimosegawa Tooru
Mol Carcinog   50(10) 781-790   Oct 2011   [Refereed]
Uno K, Iijima K, Hatta W, Koike T, Abe Y, Asano N, Kusaka G, Shimosegawa T
Am J Gastroenterol   1923-1929   Sep 2011   [Refereed]
Yamamoto Joji, Fujishima Fumiyoshi, Ichinohasama Ryo, Imatani Akira, Asano Naoki, Harigae Hideo
Leuk Lymphoma   52(9) 1803-1805   Sep 2011   [Refereed]
Asano Naoki, Iijima Katsunori, Terai Shiho, Uno Kaname, Endo Hiroyuki, Koike Tomoyuki, Iwai Wataru, Iwabuchi Toshimitsu, Hatta Waku, Abe Yasuhiko, Imatani Akira, Shimosegawa Tooru
Case Rep Gastroenterol   5(2) 325-329   May 2011   [Refereed]
Iijima Katsunori, Ara Nobuyuki, Abe Yasuhiko, Koike Tomoyuki, Iwai Wataru, Uno Kaname, Asano Naoki, Imatani Akira, Ohara Shuichi, Shimosegawa Tooru
J Gastroenterol   46(5) 612-619   May 2011   [Refereed]
Kikuchi Ryousuke, Abe Yasuhiko, Iijima Katsunori, Koike Tomoyuki, Ara Nobuyuki, Uno Kaname, Asanuma Kiyotaka, Asano Naoki, Imatani Akira, Shimosegawa Tooru
Tohoku J Exp Med   223(1) 35-44   Apr 2011   [Refereed]
Abe Yasuhiko, Iijima Katsunori, Ohara Shuichi, Koike Tomoyuki, Ara Nobuyuki, Uno Kaname, Asano Naoki, Imatani Akira, Kato Katsuaki, Shibuya Daisuke, Shimosegawa Tooru
J Gastroenterol   46(1) 25-30   Jan 2011   [Refereed]
Activation of type I IFN signaling by NOD1 mediates mucosal host defense against Helicobacter pylori infection
Watanabe T, Asano N, Kitani A, Fuss IJ, Chiba T, Strober W
Gut Microbes      Jan 2011   [Refereed]
Endo Hiroyuki, Iijima Katsunori, Asanuma Kiyotaka, Ara Nobuyuki, Ito Hirotaka, Asano Naoki, Uno Kaname, Koike Tomoyuki, Imatani Akira, Shimosegawa Tooru
Int J Cancer   127(9) 2009-2019   Nov 2010   [Refereed]
Oikawa Tomoyuki, Iijima Katsunori, Koike Tomoyuki, Uno Kaname, Horii Toru, Iwai Wataru, Abe Yasuhiko, Asano Naoki, Imatani Akira, Shimosegawa Tooru
Scand J Gastroenterol   45(11) 1338-1344   Nov 2010   [Refereed]
NOD1-mediated mucosal host defense against Helicobacter pylori.
Watanabe T, Asano N, Kitani A, Fuss IJ, Chiba T, Strober W
International Journal of Inflammation      Jul 2010   [Refereed]
Watanabe Tomohiro, Asano Naoki, Fichtner-Feigl Stefan, Gorelick Peter L, Tsuji Yoshihisa, Matsumoto Yuko, Chiba Tsutomu, Fuss Ivan J, Kitani Atsushi, Strober Warren
J Clin Invest   120(5) 1645-1662   May 2010   [Refereed]
Ito H, Iijima K, Ara N, Asanuma K, Endo H, Asano N, Koike T, Abe Y, Imatani A, Shimosegawa T
Scand J Gastroenterol   45(3) 282-291   Mar 2010   [Refereed]
Asonuma Sho, Imatani Akira, Asano Naoki, Oikawa Tomoyuki, Konishi Hidetomo, Iijima Katsunori, Koike Tomoyuki, Ohara Shuichi, Shimosegawa Tooru
Am J Physiol Gastrointest Liver Physiol   297(2) G312-22   Aug 2009   [Refereed]
Strober W, Kitani A, Fuss I, Asano N, Watanabe T
Mucosal Immunology      Nov 2008   [Refereed]
Notch1 signaling and regulatory T cell function.
Asano Naoki, Watanabe Tomohiro, Kitani Atsushi, Fuss Ivan J, Strober Warren
J Immunol   180(5) 2796-2804   Mar 2008   [Refereed]
Watanabe Tomohiro, Asano Naoki, Murray Peter J, Ozato Keiko, Tailor Prafullakumar, Fuss Ivan J, Kitani Atsushi, Strober Warren
J Clin Invest   118(2) 545-559   Feb 2008   [Refereed]
Yang Zhiqiong, Fuss Ivan J, Watanabe Tomohiro, Asano Naoki, Davey Michael P, Rosenbaum James T, Strober Warren, Kitani Atsushi
Gastroenterology   133(5) 1510-1521   Nov 2007   [Refereed]
Ohyauchi M, Imatani A, Yonechi M, Asano N, Miura A, Iijima K, Koike T, Sekine H, Ohara S, Shimosegawa T
Gut   54(3) 330-335   Mar 2005   [Refereed]
Adachi Hisanobu, Suzuki Takehiro, Abe Michiaki, Asano Naoki, Mizutamari Hiroya, Tanemoto Masayuki, Nishio Toshiyuki, Onogawa Tohru, Toyohara Takafumi, Kasai Satoshi, Satoh Fumitoshi, Suzuki Masanori, Tokui Taro, Unno Michiaki, Shimosegawa Tooru, Matsuno Seiki, Ito Sadayoshi, Abe Takaaki
Am J Physiol Renal Physiol   285(6) F1188-97   Dec 2003   [Refereed]
Suzuki Takehiro, Onogawa Tohru, Asano Naoki, Mizutamari Hiroya, Mikkaichi Tsuyoshi, Tanemoto Masayuki, Abe Michiaki, Satoh Fumitoshi, Unno Michiaki, Nunoki Kazuo, Suzuki Masanori, Hishinuma Takanori, Goto Junichi, Shimosegawa Tooru, Matsuno Seiki, Ito Sadayoshi, Abe Takaaki
Mol Endocrinol   17(7) 1203-1215   Jul 2003   [Refereed]
Abe T, Unno M, Onogawa T, Tokui T, Kondo TN, Nakagomi R, Adachi H, Fujiwara K, Okabe M, Suzuki T, Nunoki K, Sato E, Kakyo M, Nishio T, Sugita J, Asano N, Tanemoto M, Seki M, Date F, Ono K, Kondo Y, Shiba K, Suzuki M, Ohtani H, Shimosegawa T, Iinuma K, Nagura H, Ito S, Matsuno S
Gastroenterology      Jun 2001   [Refereed]
Fujiwara K, Adachi H, Nishio T, Unno M, Tokui T, Okabe M, Onogawa T, Suzuki T, Asano N, Tanemoto M, Seki M, Shiiba K, Suzuki M, Kondo Y, Nunoki K, Shimosegawa T, Iinuma K, Ito S, Matsuno S, Abe T
Endocrinology   142(5) 2005-2012   May 2001   [Refereed]

Misc

 
日常診療で診る感染症:ヘリコバクター・ピロリ感染症 (内科)
今谷晃、浅野直喜、阿部靖彦、小池智幸、飯島克則、下瀬川徹
内科   106(5) 830-834   Nov 2011
[Barret食道の最前線 腺癌発生のメカニズム]食道胃接合部癌の臨床病理学的特徴と病態 とくにHelicobacter pylori感染と胃酸分泌の面からみた病態について (G.I.Research)
阿部靖彦、大原秀一、小池智幸、堀井享、飯島克則、浅野直喜、宇野要、荒誠之、今谷晃、下瀬川徹
G.I.Research   18(1) 24-30   Feb 2011
Watanabe Tomohiro, Asano Naoki, Kitani Atsushi, Fuss Ivan J, Chiba Tsutomu, Strober Warren
Gut Microbes   2(1) 61-65   Jan 2011
Watanabe Tomohiro, Asano Naoki, Kitani Atsushi, Fuss Ivan J, Chiba Tsutomu, Strober Warren
Int J Inflam   2010 476482-476482   Apr 2010
Strober W, Kitani A, Fuss I, Asano N, Watanabe T
Mucosal Immunol   1 Suppl 1 S5-9   Nov 2008

Books etc

 
Atlas of diagnostic imaging on digestive diseases
ASANO Naoki (Part:Contributor)
Aug 2017   

Conference Activities & Talks

 
Helicobacter pylori infection down-regulates Sox2 expression through the methylation of its KLF4 binding site
ECHIGO Hiroharu, ASANO Naoki, IMATANI, Akira, JIN Xiaoyi, MASAMUNE Atsushi
The 77th annual meeting of the Japanese Cancer Association   29 Sep 2018   
Sox2 expression is down-regulated through the methylation of its KLF4 binding site in human gastric cancer cells
Hiroharu Echigo, Naoki Asano, Akira Imatani, Xiaoyi Jin, Waku Hatta, Kiyotaka Asanuma, Kaname Uno, Tomoyuki Koike, Atsushi Masamune, Tooru Shimosegawa
DDW2018   2 Jun 2018   
ヘリコバクター・ピロリ感染はCpGアイランドのメチル化を介して胃粘膜上皮における自然免疫分子NOD1の発現を抑制する
浅野直喜、今谷晃
第76回日本癌学会学術総会   28 Sep 2017   
Insufficient NOD1 signaling induced gastric intestinal metaplasia and gastric dysplasia in Helicobacter pylori-infected mice
GI Research Academy 2017   9 Jun 2017   
Insufficiency of NOD1 leads to Helicobacter pylori-induced gastric intestinal metaplasia through induction of Cdx2
2017 Japan-NIH Joint Symposium   15 Feb 2017   

Social Contribution

 
北山市民医学講座
[Lecturer]  22 Nov 2017
市民公開講座。ピロリ菌の話題「ピロリ菌と胃がん」
栗原市医師会学術講演会
[Lecturer]  20 Jul 2017
医師対象の講演会。「ヘリコバクター・ピロリ 慢性感染が胃に及ぼす影響」
第9回元気!健康!フェアinとうほく
[Lecturer]  1 Apr 2017 - 2 Apr 2017
市民公開講座。「胃がんの原因ピロリ菌を知ろう」を担当。