論文

査読有り
2015年

On Observability of Attractors in Boolean Networks

PROCEEDINGS 2015 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE
  • Yushan Qiu
  • ,
  • Xiaoqing Cheng
  • ,
  • Wai-Ki Ching
  • ,
  • Hao Jiang
  • ,
  • Tatsuya Akutsu

開始ページ
263
終了ページ
266
記述言語
英語
掲載種別
研究論文(国際会議プロシーディングス)
DOI
10.1109/BIBM.2015.7359690
出版者・発行元
IEEE

Boolean network (BN) is a popular mathematical model for revealing the behavior of a genetic regulatory network, and observability plays a vital role in understanding the underlying network feature. However, the observability of attractor cycles, which is an interesting and important problem, has not been addressed in the literature. In this paper, we first proposed a novel problem on attractor observability in BNs. Identification of the minimum set of consecutive nodes can be used to determine uniquely the attractor cycle from the others in the network. We then develop a linear-time algorithm to identify the desired set of nodes. The proposed approaches are demonstrated and verified by numerical examples. The computational results are given to illustrate both the efficiency and effectiveness of our proposed methods.

リンク情報
DOI
https://doi.org/10.1109/BIBM.2015.7359690
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000377335600047&DestApp=WOS_CPL
ID情報
  • DOI : 10.1109/BIBM.2015.7359690
  • ISSN : 2156-1125
  • Web of Science ID : WOS:000377335600047

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