細田隆介 (Ryusuke Hosoda) - マイポータル

基本情報

所属: 札幌医科大学医学部薬理学講座助教

学位: 医学博士(札幌医科大学)

研究者番号: 20749428
J-GLOBAL ID: 201801003857685293
researchmap会員ID: B000307491

研究キーワード

研究分野

ライフサイエンス / 薬理学 /

所属学協会

論文

Transcriptional dysregulation of autophagy in the muscle of a mouse model of Duchenne muscular dystrophy

Ryuta Nakashima, Ryusuke Hosoda, Yuki Tatekoshi, Naotoshi Iwahara, Yukika Saga, Atsushi Kuno

Scientific Reports 14,(1365) 2024年1月査読有り
Resveratrol, a SIRT1 activator, attenuates aging-associated alterations in skeletal muscle and heart in mice.

Ryusuke Hosoda, Ryuta Nakashima, Masaki Yano, Naotoshi Iwahara, Seidai Asakura, Iyori Nojima, Yukika Saga, Risa Kunimoto, Yoshiyuki Horio, Atsushi Kuno

Journal of Pharmacological Sciences 2023年4月査読有り筆頭著者
No sex differences in the acute effects of caffeine on mental calculation and pulse rate in healthy college students.

Nobuyuki Kurokawa, Rumi Niwa, Kouhei Tada, Ryusuke Hosoda, Naotoshi Iwahara, Yoshiyuki Horio, Atsushi Kuno

Clinical Nutrition Open Science 2023年2月査読有り
Activation of SIRT1 promotes membrane resealing via cortactin

Naotoshi Iwahara, Kuya Azekami, Ryusuke Hosoda, Iyori Nojima, Shin Hisahara, Atsushi Kuno

Scientific Reports 12(1) 15328-15328 2022年9月12日査読有り
Downregulation of IGFBP5 contributes to replicative senescence via ERK2 activation in mouse embryonic fibroblasts

Iyori Nojima, Ryusuke Hosoda, Yuki Toda, Yoshiki Saito, Naohiro Ueda, Kouhei Horimoto, Naotoshi Iwahara, Yoshiyuki Horio, Atsushi Kuno

Aging 14(7) 2966-2988 2022年4月4日査読有り
SIRT1は脱アセチル化を介してヒストンH2AXのリン酸化を媒介しドキソルビシン誘発性心毒性を弱める(SIRT1 Mediates Histone H2AX Phosphorylation via Its Deacetylation and Counteracts Doxorubicin-induced Cardiotoxicity)

久野篤史, 細田隆介

日本循環器学会学術集会抄録集 86回 PJ21-1 2022年3月
SIRT1 in the cardiomyocyte counteracts doxorubicin-induced cardiotoxicity via regulating histone H2AX

Atsushi Kuno, Ryusuke Hosoda, Miki Tsukamoto, Tatsuya Sato, Hiromi Sakuragi, Nami Ajima, Yukika Saga, Kouhei Tada, Yoshiki Taniguchi, Naotoshi Iwahara …

Cardiovascular Research 2022年3月査読有り
Ubiquitin-dependent rapid degradation conceals a cell-protective function of cytoplasmic SIRT3 against oxidative stress

Takashi Hayashi, Takashi Matsushita, Shin Hisahara, Naotoshi Iwahara, Atsushi Kuno, Risa Kunimoto, Ryusuke Hosoda, Masaya Tanno, Shun Shimohama, Yoshiyuki Horio

The Journal of Biochemistry 171(2) 201-213 2022年2月査読有り
Aging-associated inflammation and fibrosis in arachnoid membrane

Hime Suzuki, Takeshi Mikami, Naotoshi Iwahara, Yukinori Akiyama, Masahiko Wanibuchi, Katsuya Komatsu, Rintaro Yokoyama, Tsukasa Hirano, Ryusuke Hosoda, Yoshiyuki Horio …

BMC Neurology 21(1) 169-169 2021年12月査読有り
Different Antioxidative and Antiapoptotic Effects of Piceatannol and Resveratrol

Ryusuke Hosoda, Hiroki Hamada, Daisuke Uesugi, Naotoshi Iwahara, Iyori Nojima, Yoshiyuki Horio, Atsushi Kuno

Journal of Pharmacology and Experimental Therapeutics 376(3) 385-396 2021年3月査読有り筆頭著者
SIRT1 deficiency interferes with membrane resealing after cell membrane injury

Daisuke Fujiwara, Naotoshi Iwahara, Rio Sebori, Ryusuke Hosoda, Shun Shimohama, Atsushi Kuno, Yoshiyuki Horio

PLOS ONE 14(6) e0218329-e0218329 2019年6月査読有り
Resveratrol Ameliorates Mitophagy Disturbance and Improves Cardiac Pathophysiology of Dystrophin-deficient mdx Mice

Atsushi Kuno, Ryusuke Hosoda, Rio Sebori, Takashi Hayashi, Hiromi Sakuragi, Mika Tanabe, Yoshiyuki Horio

Scientific Reports 8(1) 2018年12月査読有り
Resveratrol Decreases Oxidative Stress by Restoring Mitophagy and Improves the Pathophysiology of Dystrophin-Deficient mdx Mice

Rio Sebori, Atsushi Kuno, Ryusuke Hosoda, Takashi Hayashi, Yoshiyuki Horio

Oxidative Medicine and Cellular Longevity 2018 1-13 2018年10月査読有り
Pterostilbene and Its Glucoside Induce Type XVII Collagen Expression

Hiroki Hamada, Kei Shimoda, Yoshiyuki Horio, Tsubasa Ono, Ryusuke Hosoda, Noriyuki Nakayama, Koichi Urano

NATURAL PRODUCT COMMUNICATIONS 12(1) 85-86 2017年1月査読有り
ピセアタンノールとレスベラトロールの酸化ストレスに対する細胞保護効果の比較

細田隆介, 久野篤史, 瀬堀理生, 濱田博喜, 堀尾嘉幸

日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 88回・38回 [3P0135]-[3P0135] 2015年12月
Chloroquine potentiates temozolomide cytotoxicity by inhibiting mitochondrial autophagy in glioma cells

Yusuke S. Hori*, Ryusuke Hosoda*, Yukinori Akiyama, Rio Sebori, Masahiro Wanibuchi, Takeshi Mikami, Toshiya Sugino, Kengo Suzuki, Mitsuhisa Maruyama, Miki Tsukamoto …

JOURNAL OF NEURO-ONCOLOGY 122(1) 11-20 2015年3月査読有り筆頭著者
Regulation of FOXOs and p53 by SIRT1 Modulators under Oxidative Stress

Yusuke S. Hori*, Atsushi Kuno*, Ryusuke Hosoda*, Yoshiyuki Horio.*=equal contribution

PLoS ONE 8(9) e73875-e73875 2013年9月11日査読有り筆頭著者
Regioselective Hydroxylation and Glucosylation of Flavanones with Cultured Plant Cells of Eucalyptus perriniana

Ryusuke Hosoda, Yoshiyuki Horio, Kei Shimoda, Manabu Hamada, Hatsuyuki Hamada, Hiroki Hamada

NATURAL PRODUCT COMMUNICATIONS 8(7) 905-906 2013年7月査読有り筆頭著者
Resveratrol Improves Cardiomyopathy in Dystrophin-deficient Mice through SIRT1 Protein-mediated Modulation of p300 Protein

Atsushi Kuno, Yusuke S. Hori, Ryusuke Hosoda, Masaya Tanno, Tetsuji Miura, Kazuaki Shimamoto, Yoshiyuki Horio

JOURNAL OF BIOLOGICAL CHEMISTRY 288(8) 5963-5972 2013年2月査読有り
Differential cell-protective function of two resveratrol (trans-3,5,4'-trihydroxystilbene) glucosides against oxidative stress.

Ryusuke Hosoda, Atsushi Kuno, Yusuke S Hori, Katsuki Ohtani, Nobutaka Wakamiya, Azusa Oohiro, Hiroki Hamada, Yoshiyuki Horio

The Journal of pharmacology and experimental therapeutics 344(1) 124-32 2013年1月査読有り筆頭著者