Michael James Carr

Profile Information

Affiliation: Invited Faculty Member (Visiting Associate Professor), Research Center for Zoonosis Control International Collaboration Unit, Hokkaido University

Degree: B.Sc. (Hons) Biochemistry(University College Galway, Ireland)
Ph.D. Cell and Molecular Biology(University of Edinburgh)

Contact information: gicore-icuczc.hokudai.ac.jp
Researcher number: 70769588
J-GLOBAL ID: 201601003439027994
researchmap Member ID: B000267099

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Research Interests

Research Areas

Life sciences / Molecular biology / Virology

Research History

Jul, 2020 - Present

Invited Faculty Member (Visiting Associate Professor), International Collaboration Unit, Research Center for Zoonosis Control, Hokkaido University
Nov, 2008 - Present

Clinical Scientist, National Virus Reference Laboratory (NVRL), University College Dublin (UCD), Belfield, Dublin 4, Ireland
Apr, 2019 - Mar, 2020

Associate Professor, Global Station for Zoonosis Control, Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University
Jun, 2015 - Mar, 2019

Assistant Professor, Global Station for Zoonosis Control, Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University
May, 2006 - Oct, 2008

Research Scientist, National Virus Reference Laboratory (NVRL), University College Dublin (UCD), Belfield, Dublin 4, Ireland
May, 2002 - Mar, 2006

Research Scientist, Department of Clinical Microbiology, St. James’s Hospital, Trinity College Dublin (TCD), Dublin 8, Ireland
Jan, 2000 - Dec, 2001

Post-Doctoral Fellow, University of Edinburgh, UK

Education

Aug, 1995 - Sep, 1999

Ph.D. Cell and Molecular Biology, University of Edinburgh, UK
Sep, 1992 - May, 1995

B.Sc. (Hons) Biochemistry, University College Galway, Ireland

Papers

Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses.

Shinsuke Toba, Akihiko Sato, Makoto Kawai, Yoshiyuki Taoda, Yuto Unoh, Shinji Kusakabe, Haruaki Nobori, Shota Uehara, Kentaro Uemura, Keiichi Taniguchi …

Proceedings of the National Academy of Sciences of the United States of America, 119(36) e2206104119, Sep 6, 2022
Co-Circulation of Multiple Serotypes of Bluetongue Virus in Zambia.

Herman M Chambaro, Michihito Sasaki, Edgar Simulundu, Isaac Silwamba, Yona Sinkala, Gabriel Gonzalez, David Squarre, Paul Fandamu, Caesar H Lubaba, Musso Munyeme …

Viruses, 12(9), Aug 31, 2020
Host ESCRT factors are recruited during chikungunya virus infection and are required for the intracellular viral replication cycle

Shiho Torii, Yasuko Orba, Michihito Sasaki, Koshiro Tabata, Yuji Wada, Michael Carr, Jody Hobson-Peters, Roy A. Hall, Ayato Takada, Takasuke Fukuhara …

JOURNAL OF BIOLOGICAL CHEMISTRY, 295(23) 7941-7957, Jun, 2020 Peer-reviewed
Evidence for exposure of asymptomatic domestic pigs to African swine fever virus during an inter-epidemic period in Zambia.

Herman M Chambaro, Michihito Sasaki, Yona Sinkala, Gabriel Gonzalez, David Squarre, Paul Fandamu, Caesar Lubaba, Liywalii Mataa, Misheck Shawa, Kabemba E Mwape …

Transboundary and emerging diseases, 67(6) 2741-2752, May 20, 2020 Peer-reviewed
Interferon lambda rs368234815 ΔG/ΔG is associated with higher CD4+:CD8+ T-cell ratio in treated HIV-1 infection.

Inês T Freitas, Willard Tinago, Hirofumi Sawa, Julie McAndrews, Brenda Doak, Charlotte Prior-Fuller, Gerard Sheehan, John S Lambert, Eavan Muldoon, Aoife G Cotter …

AIDS research and therapy, 17(1) 13-13, Apr 15, 2020
Pediatric Infections by Human mastadenovirus C Types 2, 89, and a Recombinant Type Detected in Japan between 2011 and 2018.

Kenichiro Takahashi, Gabriel Gonzalez, Masaaki Kobayashi, Nozomu Hanaoka, Michael J Carr, Masami Konagaya, Naomi Nojiri, Miki Ogi, Tsuguto Fujimoto

Viruses, 11(12), Dec 6, 2019
Enterovirus-Associated Hand-Foot-and-Mouth Disease and Neurological Complications in Japan and the Rest of the World

Gabriel Gonzalez, Michael J. Carr, Masaaki Kobayashi, Nozomu Hanaoka, Tsuguto Fujimoto

International Journal of Molecular Sciences, 20(20) 1-16, Oct, 2019 Peer-reviewedInvited
Upregulated expression of the antioxidant sestrin 2 identified by transcriptomic analysis of Japanese encephalitis virus-infected SH-SY5Y neuroblastoma cells.

Carr M, Gonzalez G, Martinelli A, Wastika CE, Ito K, Orba Y, Sasaki M, Hall WW, Sawa H

Virus genes, 55(5) 630-642, Oct, 2019 Peer-reviewed
Serological evidence of Zika virus infection in non-human primates in Zambia.

Wastika CE, Sasaki M, Yoshii K, Anindita PD, Hang'ombe BM, Mweene AS, Kobayashi S, Kariwa H, Carr MJ, Hall WW …

Archives of virology, 164(8) 2165-2170, Jun, 2019 Peer-reviewed
Discovery and genetic characterization of diverse smacoviruses in Zambian non-human primates.

Anindita PD, Sasaki M, Gonzalez G, Phongphaew W, Carr M, Hang'ombe BM, Mweene AS, Ito K, Orba Y, Sawa H

Scientific reports, 9(1) 5045-5045, Apr, 2019 Peer-reviewed
Publisher Correction: Discovery and genetic characterization of diverse smacoviruses in Zambian non-human primates (Scientific Reports, (2019), 9, 1, (5045), 10.1038/s41598-019-41358-z)

Anindita, P.D., Sasaki, M., Gonzalez, G., Phongphaew, W., Carr, M., Hang’ombe, B.M., Mweene, A.S., Ito, K., Orba, Y., Sawa, H.

Scientific Reports, 9(1) 8502-8502, 2019 Peer-reviewed
Genomic characterization of human adenovirus type 4 strains isolated worldwide since 1953 identifies two separable phylogroups evolving at different rates from their most recent common ancestor

Gabriel Gonzalez, Camden R. Bair, Daryl M. Lamson, Hidemi Watanabe, Laura Panto, Michael J. Carr, Adriana E. Kajon

Virology, 538 11-23, 2019 Peer-reviewed
Identification of group A rotaviruses from Zambian fruit bats provides evidence for long-distance dispersal events in Africa.

Sasaki M, Kajihara M, Changula K, Mori-Kajihara A, Ogawa H, Hang'ombe BM, Mweene AS, Simuunza M, Yoshida R, Carr M …

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 63 104-109, Sep, 2018 Peer-reviewed
Rapid detection of hand, foot and mouth disease enterovirus genotypes by multiplex PCR

Min Wang, Qian Ren, Zhenjie Zhang, Lehai Zhang, Michael J. Carr, Juan Li, Hong Zhou, Weifeng Shi

Journal of Virological Methods, 258 7-12, Aug 1, 2018 Peer-reviewed
Single amino acid mutation in dengue virus NS4B protein has opposing effects on viral proliferation in mammalian and mosquito cells.

Fujiki J, Nobori H, Sato A, Sasaki M, Carr M, Hall WW, Orba Y, Sawa H

Japanese journal of infectious diseases, 71(6) 448-454, Jul, 2018 Peer-reviewed
Discovery of Mwinilunga alphavirus: A novel alphavirus in Culex mosquitoes in Zambia.

Shiho Torii, Yasuko Orba, Bernard M Hang'ombe, Aaron S Mweene, Yuji Wada, Paulina D Anindita, Wallaya Phongphaew, Yongjin Qiu, Masahiro Kajihara, Akina Mori-Kajihara …

Virus research, 250 31-36, May 2, 2018 Peer-reviewed
The Role of Heparan Sulfate Proteoglycans as an Attachment Factor for Rabies Virus Entry and Infection.

Sasaki M, Anindita PD, Ito N, Sugiyama M, Carr M, Fukuhara H, Ose T, Maenaka K, Takada A, Hall WW …

The Journal of infectious diseases, 217(11) 1740-1749, May, 2018 Peer-reviewed
Development of a rapid and quantitative method for the analysis of viral entry and release using a NanoLuc luciferase complementation assay

Michihito Sasaki, Paulina D. Anindita, Wallaya Phongphaew, Michael Carr, Shintaro Kobayashi, Yasuko Orba, Hirofumi Sawa

VIRUS RESEARCH, 243 69-74, Jan, 2018 Peer-reviewed
Association of interferon lambda polymorphisms with elevated baseline viral loads in chronic hepatitis C virus genotype 6 infection

Linh Thuy Nguyen, Dzung Van Nguyen, Michael J. Carr, William W. Hall, Lan Anh Nguyen

Archives of Virology, 163(1) 115-124, Jan 1, 2018 Peer-reviewed
Identification of the same polyomavirus species in different African horseshoe bat species is indicative of short-range host-switching events.

Carr M, Gonzalez G, Sasaki M, Dool SE, Ito K, Ishii A, Hang'ombe BM, Mweene AS, Teeling EC, Hall WW …

The Journal of general virology, 98(11) 2771-2785, Nov, 2017 Peer-reviewed

Misc.

HOMOZYGOSITY FOR HLA-C2 ALLELES IS NEGATIVELY ASSOCIATED WITH TREATMENT RESPONSE WITH PEGLYATED INTERFERON-gamma AND RIBAVIRIN IN HEPATITIS C GENOTYPE 1 INFECTED INDIVIDUALS

M. Collison, J. L. Chin, A. Abu Shanab, R. MacNicholas, J. Connell, M. Carr, W. Hall, P. A. McCormick

GUT, 62 A5-U21, Aug, 2013
Reactivation of latent viral infections in patients receiving natalizumab for the treatment of multiple sclerosis

Cillian F. De Gascun, Michael J. Carr, Roisin M. Lonergan, Suzie Coughlan, Michael W. Hutchinson, Niall J. Tubridy, William W. Hall

JOURNAL OF NEUROVIROLOGY, 15 22-23, 2009
NATALIZUMAB IN MULTIPLE SCLEROSIS: USE OF CD4:CD8 RATIO AND JC VIRAL LOAD MONITORING TO PREDICT PROGRESSIVE MULTIFOCAL LEUCOENCEPHALOPATHY

C. F. De Gascun, R. Lonergan, L. Costelloe, J. Fletcher, M. Carr, S. Coughlan, M. Duggan, K. Doyle, S. Jordan, W. W. Hall …

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 80(1) 125-125, Jan, 2009
REPLICATION AND REACTIVATION OF BK VIRUS WITH NATALIZUMAB THERAPY

R. Lonergan, L. Costelloe, C. F. De Gascun, M. Carr, S. Coughlan, M. Duggan, K. Doyle, S. Jordan, W. W. Hall, M. Hutchinson …

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 80(1) 126-126, Jan, 2009

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