Apr, 2014 - Mar, 2018
Characterization of golgins in secretion and Golgi
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C) Grant-in-Aid for Scientific Research (C)
- Grant number
- 26440055
- Japan Grant Number (JGN)
- JP26440055
- Grant amount
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- (Total)
- 5,070,000 Japanese Yen
- (Direct funding)
- 3,900,000 Japanese Yen
- (Indirect funding)
- 1,170,000 Japanese Yen
We have shown that secretion increases and the structure of the Golgi changes when knocking down giantin, which is one of the Golgin protein group. In this research project, to clarify the molecular mechanisms underlying this phenomenon as the ultimate goal, the structure of the Golgi was analyzed in detail using electron beam tomography and the like. Also, during this time, we discovered a novel small molecule involved in secretion regulation, so we performed the characterization of new molecules, as well.
- Link information
- ID information
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- Grant number : 26440055
- Japan Grant Number (JGN) : JP26440055
List of results of the research project
Narrowing down
Papers
3-
Methods in Molecular Biology, 275-285, Dec 14, 2022 Peer-reviewedInvitedCorresponding author
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Methods in Molecular Biology, 235-246, Dec 14, 2022 Peer-reviewedInvitedLead authorCorresponding author
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Frontiers in Cell and Developmental Biology, 7, Aug 27, 2019 Peer-reviewedInvitedLead authorCorresponding author