Michikazu Nakai

Profile Information

Affiliation: 室長, 循環器病統合情報センター統計解析室, 国立研究開発法人国立循環器病研究センター

ORCID ID: https://orcid.org/0000-0003-2240-1510
J-GLOBAL ID: 202001017894488782
researchmap Member ID: R000008717

Research Interests

Research Areas

Research History

Apr, 2022 - Present

室長, 医学統計研究部臨床疫学解析室, 国立研究開発法人国立循環器病研究センター
Sep, 2021 - Present

室長, 情報利用促進部統計解析室, 国立研究開発法人国立循環器病研究センター
Apr, 2019 - Aug, 2021

Head, Section of Statistics and Data Analysis, Center for Cerebral and Cardiovascular Disease Information, National Cerebral and Cardiovascular Center, R
Apr, 2015 - Mar, 2019

Senior Researcher, Section of Statistics and Data Analysis, Cener for Cerebral and Cardiovascular Disease Information, National Cerebral and Cardiovascular Center
Apr, 2012 - Mar, 2015

Postdoctoral Researcher, Department of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center, Research Institute
Sep, 2010 - Mar, 2011

Assistant Professor, Innovation Center for Medical Redox Navigation, Kyushu University

Education

Sep, 2006 - May, 2010

Computational Science and Statistics, South Dakota State University

Awards

Papers

197

Reduction in Planned Percutaneous Coronary Interventions After the Policy Change for Ischemia Assessment in Japan

Koshiro Kanaoka, Yoshitaka Iwanaga, Michikazu Nakai, Yuichi Nishioka, Tomoya Myojin, Katsuki Okada, Tatsuya Noda, Yoshihiro Miyamoto, Yoshihiko Saito, Tomoaki Imamura

JACC: Asia, Feb, 2023
Validity of Diagnostic Algorithms for Cardiovascular Diseases in Japanese Health Insurance Claims

Koshiro Kanaoka, Yoshitaka Iwanaga, Katsuki Okada, Satoshi Terasaki, Yuichi Nishioka, Michikazu Nakai, Daisuke Kamon, Tomoya Myojin, Tsunenari Soeda, Tatsuya Noda, Manabu Horii, Yasushi Sakata, Yoshihiro Miyamoto, Yoshihiko Saito, Tomoaki Imamura

Circulation Journal, Jan 28, 2023
Hospital- and Patient-level Analysis of Quality Indicators in Acute Coronary Syndrome Care: A Nationwide Database Study

Koshiro Kanaoka, Yoshitaka Iwanaga, Michikazu Nakai, Yuichi Nishioka, Tomoya Myojin, Shinichiro Kubo, Katsuki Okada, Tsunenari Soeda, Tatsuya Noda, Yasushi Sakata, Yoshihiro Miyamoto, Yoshihiko Saito, Tomoaki Imamura

Canadian Journal of Cardiology, Dec, 2022
Multifactorial Effects of Outpatient Cardiac Rehabilitation in Patients with Heart Failure: A Nationwide Retrospective Cohort Study

Koshiro Kanaoka, Yoshitaka Iwanaga, Michikazu Nakai, Yuichi Nishioka, Tomoya Myojin, Shinichiro Kubo, Katsuki Okada, Tatsuya Noda, Yasushi Sakata, Yoshihiro Miyamoto, Yoshihiko Saito, Tomoaki Imamura

European Journal of Preventive Cardiology, Nov 15, 2022
Liver stiffness assessed by magnetic resonance elastography predicts clinical outcomes in patients with heart failure and without chronic liver disease.

Atsushi Tada, Toshiyuki Nagai, Yoshiya Kato, Kazunori Omote, Noriko Oyama-Manabe, Satonori Tsuneta, Yusuke Kudo, Mutsumi Nishida, Michikazu Nakai, Yuki Takahashi, Kohei Saiin, Seiichiro Naito, Yuta Kobayashi, Sakae Takenaka, Yoshifumi Mizuguchi, Kiwamu Kamiya, Takao Konishi, Takuma Sato, Kohsuke Kudo, Toshihisa Anzai

European radiology, 33(3) 2062-2074, Nov 3, 2022
Age-dependent association of discharge heart-failure medications with clinical outcomes in a super-aged society.

Michikazu Nakai, Yoshitaka Iwanaga, Koshiro Kanaoka, Yoko Sumita, Yuichi Nishioka, Tomoya Myojin, Shinichiro Kubo, Katsuki Okada, Tsunenari Soeda, Tatsuya Noda, Yasushi Sakata, Tomoaki Imamura, Yoshihiko Saito, Satoshi Yasuda, Yoshihiro Miyamoto

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 155 113761-113761, Nov, 2022 Peer-reviewed
The Japanese Catheter Ablation Registry (J-AB): Annual report in 2020.

Kengo Kusano, Teiichi Yamane, Koichi Inoue, Misa Takegami, Yoko M Nakao, Michikazu Nakai, Koshiro Kanaoka, Reina Tonegawa-Kuji, Koji Miyamoto, Yu-Ki Iwasaki, Seiji Takatsuki, Kohki Nakamura, Yoshitaka Iwanaga, Wataru Shimizu

Journal of arrhythmia, 38(5) 675-681, Oct, 2022
Clinical picture of the duration of venoarterial extracorporeal membrane oxygenation: analysis from JROAD-DPC.

Kazuo Sakamoto, Tetsuya Matoba, Michikazu Nakai, Yoshio Tahara, Takahiro Nakashima, Hayato Hosoda, Yoshihiro Miyamoto, Kunihiro Nishimura, Yoko Sumita, Tsukasa Yagi, Kenzo Ichimura, Naohiro Yonemoto, Eizo Tachibana, Ken Nagao, Takanori Ikeda, Naoki Sato, Hiroyuki Tsutsui

Heart and vessels, 38(2) 228-235, Sep 29, 2022
Hospital-associated disability and hospitalization costs for acute heart failure stratified by body mass index- insight from the JROAD/JROAD-DPC database.

Masato Ogawa, Naofumi Yoshida, Michikazu Nakai, Koshiro Kanaoka, Yoko Sumita, Yuji Kanejima, Takuo Emoto, Yoshihiro Saito, Hiroyuki Yamamoto, Yoshitada Sakai, Yushi Hirota, Wataru Ogawa, Yoshitaka Iwanaga, Yoshihiro Miyamoto, Tomoya Yamashita, Kazuhiro P Izawa, Ken-Ichi Hirata

International journal of cardiology, Aug 24, 2022
Contemporary use of SGLT2 inhibitors in heart failure patients with diabetes mellitus: a comparison of DPP4 inhibitors in a nationwide electric health database of the superaged society.

Michikazu Nakai, Yoshitaka Iwanaga, Koshiro Kanaoka, Yoko Sumita, Yuichi Nishioka, Tomoya Myojin, Shinichiro Kubo, Katsuki Okada, Tsunenari Soeda, Tatsuya Noda, Yasushi Sakata, Tomoaki Imamura, Yoshihiko Saito, Satoshi Yasuda, Yoshihiro Miyamoto

Cardiovascular diabetology, 21(1) 157-157, Aug 13, 2022
Clinical Characteristics and Outcomes of Patients Presenting With Acute Myocardial Infarction Without Cardiogenic Shock.

Hiroshi Okamoto, Takeshi Nishi, Masanobu Ishii, Kenichi Tsujita, Satoshi Koto, Michikazu Nakai, Yoko Sumita, Yoshitaka Iwanaga, Satoaki Matoba, Yoshio Kobayashi, Ken-Ichi Hirata, Yutaka Hikichi, Hiroyoshi Yokoi, Yuji Ikari, Shiro Uemura

Circulation journal : official journal of the Japanese Circulation Society, 86(10) 1527-1538, Aug 11, 2022
Hospitalizations for Cardiovascular Diseases During the Early Stage of the COVID-19 Pandemic in Japan.

Tadafumi Sugimoto, Atsushi Mizuno, Daisuke Yoneoka, Shingo Matsumoto, Chisa Matsumoto, Yuya Matsue, Mari Ishida, Michikazu Nakai, Yoshitaka Iwanaga, Yoshihiro Miyamoto, Koichi Node

Circulation reports, 4(8) 353-362, Aug 10, 2022
Mortality and 30-day Readmission Rates Following Inpatient Leadless Pacemaker Implantation: Insights from the Nationwide Readmissions Database.

Reina Tonegawa-Kuji, Koshiro Kanaoka, Makoto Mori, Michikazu Nakai, Yoshitaka Iwanaga

The Canadian journal of cardiology, Aug 10, 2022
Quality indicators for acute cardiovascular diseases: a scoping review.

Koshiro Kanaoka, Yoshitaka Iwanaga, Yasushi Tsujimoto, Akihiro Shiroshita, Takaaki Suzuki, Michikazu Nakai, Yoshihiro Miyamoto

BMC health services research, 22(1) 862-862, Jul 5, 2022
A new biomarker of cardiac resynchronization therapy response: cGMP to mature BNP ratio.

Yasuhiro Yokoyama, Naoya Kataoka, Michikazu Nakai, Ayaka Matsuo, Akihiro Fujiwara, Akinori Wakamiya, Nobuhiko Ueda, Kenzaburo Nakajima, Tsukasa Kamakura, Mitsuru Wada, Kenichiro Yamagata, Kohei Ishibashi, Yuko Inoue, Koji Miyamoto, Satoshi Nagase, Takashi Noda, Takeshi Aiba, Hiroyuki Takahama, Chisato Izumi, Koichiro Kinugawa, Naoto Minamino, Kengo Kusano

Journal of cardiology, 79(6) 727-733, Jun, 2022
Trends and Factors Associated With Cardiac Rehabilitation Participation - Data From Japanese Nationwide Databases.

Koshiro Kanaoka, Yoshitaka Iwanaga, Nagaharu Fukuma, Michikazu Nakai, Yoko Sumita, Yuichi Nishioka, Katsuki Okada, Tatsuya Noda, Yasushi Sakata, Tomoaki Imamura, Yoshihiro Miyamoto

Circulation journal : official journal of the Japanese Circulation Society, May 27, 2022
Temporal Trends in the Practice Pattern for Sleep-Disordered Breathing in Patients With Cardiovascular Diseases in Japan - Insights From the Japanese Registry of All Cardiac and Vascular Diseases - Diagnosis Procedure Combination.

Ryohei Takeishi, Akiomi Yoshihisa, Yu Hotsuki, Fumiya Anzai, Yu Sato, Yoko Sumita, Michikazu Nakai, Tomofumi Misaka, Yasuchika Takeishi

Circulation journal : official journal of the Japanese Circulation Society, Apr 27, 2022
Etiology and Outcome of Ischemic Stroke in Patients With Renal Impairment Including Chronic Kidney Disease: Japan Stroke Data Bank.

Kaori Miwa, Masatoshi Koga, Michikazu Nakai, Sohei Yoshimura, Yusuke Sasahara, Junpei Koge, Kazutaka Sonoda, Akiko Ishigami, Yoshitaka Iwanaga, Yoshihiro Miyamoto, Shotai Kobayashi, Kazuo Minematsu, Kazunori Toyoda

Neurology, 98(17) e1738-e1747-E1747, Apr 26, 2022
Renin-angiotensin system blocker and the COVID-19 aggravation in patients with hypertension, diabetes, renal failure, Cerebro-cardiovascular disease, or pulmonary disease: Report by the COVID-19 Registry Japan.

Fumiki Yoshihara, Hiroshi Ohtsu, Michikazu Nakai, Shinya Tsuzuki, Kayoko Hayakawa, Mari Terada, Nobuaki Matsunaga, Satoshi Yasuda, Hisao Ogawa, Norio Ohmagari

Journal of cardiology, 80(4) 292-297, Apr 8, 2022
Outcomes of Venoarterial Extracorporeal Membrane Oxygenation Plus Intra-Aortic Balloon Pumping for Treatment of Acute Myocardial Infarction Complicated by Cardiogenic Shock.

Takeshi Nishi, Masanobu Ishii, Kenichi Tsujita, Hiroshi Okamoto, Satoshi Koto, Michikazu Nakai, Yoko Sumita, Yoshitaka Iwanaga, Satoaki Matoba, Yoshio Kobayashi, Ken-Ichi Hirata, Yutaka Hikichi, Hiroyoshi Yokoi, Yuji Ikari, Shiro Uemura

Journal of the American Heart Association, 11(7) e023713, Apr 5, 2022

Misc.

COVID-19 REGISTRY JAPANデータを用いたレニン・アンジオテンシン(RA)抑制薬とCOVID-19重症化との関連性評価

吉原史樹, 大津洋, 中井陸運, 都築慎也, 早川佳代子, 寺田麻里, 松永展明, 安田聡, 小川久雄, 大曲貴夫

日本腎臓学会誌, 64(3) 316-316, May, 2022
What are the Requirements for an Aortic Emergency Center Hospital?: Insights from JROAD-DPC Data(和訳中)

山口徹雄, 中井陸運, 宮本恵宏, 松田均, 大北裕, 上田友哉, 荻野均

日本循環器学会学術集会抄録集, 86回 PL03-2, Mar, 2022
急性心筋梗塞の現状と院内・院外の死亡率低下に向けた取り組み(Impact of Sufficient Cardiovascular Care Supply on In-Hospital Mortality in Patients with Acute Myocardial Infarction Complicated by Cardiogenic Shock)

辻田賢一, 石井正将, 岡本公志, 厚東識志, 西毅, 中井陸運, 住田陽子, 岩永善高, 的場聖明, 平田健一, 挽地裕, 横井宏佳, 伊苅裕二, 上村史朗

日本循環器学会学術集会抄録集, 86回 SY12-3, Mar, 2022
Does Physician-induced Demand Exist in Acute Cardiovascular Inpatient Care in Japan? An Analysis of 3,546,181 Admissions from JROAD Database(和訳中)

大山善昭, 中井陸運, 住田陽子, 岩永善高, 中村哲也, 倉林正彦, 根岸一明

日本循環器学会学術集会抄録集, 86回 PJ35-1, Mar, 2022
精神科病院における改正健康増進法前後の喫煙環境と禁煙外来設置状況

川合厚子, 北田雅子, 中井陸運, 安陪隆明, 飯田真美, 大坪陽子, 倉本剛史, 清水隆裕, 高野義久, 高畑裕美, 土井たかし, 長谷川純一, 三間聡, 加濃正人, 藤原久義, 日本禁煙学会禁煙治療と支援委員会

日本禁煙学会学術総会プログラム・抄録集, 15回 128-128, Oct, 2021
大規模医療データベースを活用した臨床疫学研究全国的な悉皆性を有する循環器データベースの構築

中井陸運

日本高血圧学会総会プログラム・抄録集, 43回 169-169, Oct, 2021
精神科病院における改正健康増進法前後の喫煙環境と禁煙外来設置状況

川合厚子, 北田雅子, 中井陸運, 安陪隆明, 飯田真美, 大坪陽子, 倉本剛史, 清水隆裕, 高野義久, 高畑裕美, 土井たかし, 長谷川純一, 三間聡, 加濃正人, 藤原久義, 日本禁煙学会禁煙治療と支援委員会

日本禁煙学会学術総会プログラム・抄録集, 15回 128-128, Oct, 2021
電子カルテデータベースを活用した心血管疾患の治療の質とアウトカムの評価方法 JROAD、NDB、KDB(How to Assess the Quality of Care and Outcomes for Cardiovascular Diseases Using Electronic Health Databases; JROAD, NDB, and KDB)

金岡幸嗣朗, 寺崎智志, 西岡祐一, 久保慎一郎, 中井陸運, 住田陽子, 岡田佳築, 添田恒有, 野田龍也, 渡邉真言, 川上利香, 坂田泰史, 宮本恵宏, 今村知明, 斎藤能彦

日本循環器学会学術集会抄録集, 85回 PL01-6, Mar, 2021
循環器領域における保険診療の課題と対策:技術評価の時代へ(健保対策委員会) 心房細動に対するラジオ波焼灼術とクライオバルーンアブレーションの入院費用の比較 JROAD-DPC Databaseの解析(Comparison of Hospitalization Costs between Radiofrequency and Cryoballoon Ablation of Atrial Fibrillation: Analysis of JROAD-DPC Database)

横山靖浩, 宮本康二, 中井陸運, 住田陽子, 上田暢彦, 中島健三郎, 和田暢, 山形研一郎, 石橋耕平, 井上優子, 永瀬聡, 野田崇, 相庭武司, 西村邦宏, 宮本恵宏, 草野研吾

日本循環器学会学術集会抄録集, 85回 SY03-3, Mar, 2021
医師偏在へき地医療の現状と解決への取り組み人口密度が急性心筋梗塞と心不全の院内死亡率に与える影響 JROAD-DPC Datasetからの知見(Impact of Population Density on In-hospital Mortality in Acute Myocardial Infarction and Heart Failure: Insights from JROAD-DPC Dataset)

小西正紹, 松澤泰志, 郷原正臣, 海老名俊明, 小菅雅美, 日比潔, 中井陸運, 安田聡, 中山尚貴, 西村邦宏, 宮本恵宏, 竹内一郎, 斎藤能彦, 筒井裕之, 小室一成, 小川久雄, 田村功一, 木村一雄

日本循環器学会学術集会抄録集, 85回 SY08-1, Mar, 2021
日本におけるたこつぼ型心筋症の罹患率の季節性変動 JROAD-DPC Registryを用いた全国規模の研究(The Seasonal Variation in the Incidence of Takotsubo Cardiomyopathy in Japan: A Nationwide Study Using JROAD-DPC Registry)

金岡幸嗣朗, 寺崎智志, 中井陸運, 住田陽子, 渡邉真言, 川上利香, 宮本恵宏, 斎藤能彦

日本循環器学会学術集会抄録集, 85回 TP13-2, Mar, 2021
循環器疾患を有する日本人患者における病院実績と転帰の関連(Association between Hospital Performance and Outcome among Japanese Patients with Cardiovascular Disease)

中尾一泰, 中井陸運, 住田陽子, 中尾葉子, 宮本恵宏, 小川久雄

日本循環器学会学術集会抄録集, 85回 TP13-3, Mar, 2021
日本における成人先天性心疾患の予定外の入院による臨床的負担の現状(The Current Clinical Burden of Unplanned Hospitalization of Adult Congenital Heart Disease in Japan)

石津智子, 中井陸運, 住田陽子, 川松直人, 倉岡彩子, 増田慶太, 佐藤希美, 山本昌良, 町野智子, 家田真樹

日本循環器学会学術集会抄録集, 85回 FRS4-1, Mar, 2021
日本における成人先天性心疾患患者の心不全 JROAD-DPC研究からの報告(Heart Failure in Adult Congenital Heart Disease in Japan; A Report from JROAD-DPC Study)

石津智子, 中井陸運, 住田陽子, 川松直人, 倉岡彩子, 増田慶太, 佐藤希美, 山本昌良, 町野智子, 家田真樹

日本循環器学会学術集会抄録集, 85回 OJ34-2, Mar, 2021
How to Assess the Quality of Care and Outcomes for Cardiovascular Diseases Using Electronic Health Databases; JROAD, NDB, and KDB(和訳中)

金岡幸嗣朗, 寺崎智志, 西岡祐一, 久保慎一郎, 中井陸運, 住田陽子, 岡田佳築, 添田恒有, 野田龍也, 渡邉真言, 川上利香, 坂田泰史, 宮本恵宏, 今村知明, 斎藤能彦

日本循環器学会学術集会抄録集, 85回 PL01-6, Mar, 2021
循環器領域における保険診療の課題と対策:技術評価の時代へ(健保対策委員会)(Comparison of Hospitalization Costs between Radiofrequency and Cryoballoon Ablation of Atrial Fibrillation: Analysis of JROAD-DPC Database)

横山靖浩, 宮本康二, 中井陸運, 住田陽子, 上田暢彦, 中島健三郎, 和田暢, 山形研一郎, 石橋耕平, 井上優子, 永瀬聡, 野田崇, 相庭武司, 西村邦宏, 宮本恵宏, 草野研吾

日本循環器学会学術集会抄録集, 85回 SY03-3, Mar, 2021
医師偏在へき地医療の現状と解決への取り組み(Impact of Population Density on In-hospital Mortality in Acute Myocardial Infarction and Heart Failure: Insights from JROAD-DPC Dataset)

小西正紹, 松澤泰志, 郷原正臣, 海老名俊明, 小菅雅美, 日比潔, 中井陸運, 安田聡, 中山尚貴, 西村邦宏, 宮本恵宏, 竹内一郎, 斎藤能彦, 筒井裕之, 小室一成, 小川久雄, 田村功一, 木村一雄

日本循環器学会学術集会抄録集, 85回 SY08-1, Mar, 2021
The Seasonal Variation in the Incidence of Takotsubo Cardiomyopathy in Japan: A Nationwide Study Using JROAD-DPC Registry(和訳中)

金岡幸嗣朗, 寺崎智志, 中井陸運, 住田陽子, 渡邉真言, 川上利香, 宮本恵宏, 斎藤能彦

日本循環器学会学術集会抄録集, 85回 TP13-2, Mar, 2021
The Current Clinical Burden of Unplanned Hospitalization of Adult Congenital Heart Disease in Japan(和訳中)

石津智子, 中井陸運, 住田陽子, 川松直人, 倉岡彩子, 増田慶太, 佐藤希美, 山本昌良, 町野智子, 家田真樹

日本循環器学会学術集会抄録集, 85回 FRS4-1, Mar, 2021
Heart Failure in Adult Congenital Heart Disease in Japan; A Report from JROAD-DPC Study(和訳中)

石津智子, 中井陸運, 住田陽子, 川松直人, 倉岡彩子, 増田慶太, 佐藤希美, 山本昌良, 町野智子, 家田真樹

日本循環器学会学術集会抄録集, 85回 OJ34-2, Mar, 2021

Teaching Experience

Apr, 2020 - Aug, 2020

Medical Statistics 1 (Kobe Pharmaceutical University)
Sep, 2020 - Dec, 2020

Medical Statistics 2 (Kobe Pharmaceutical University)

Professional Memberships

Research Projects

ビッグデータ・機械学習を用いたアブレーション治療の有効性・安全性予測モデルの作成

科学研究費助成事業基盤研究(B), 日本学術振興会, Apr, 2022 - Mar, 2025

草野研吾, 山根禎一, 清水渉, 中井陸運, 岩永善高
心血管病発症における血管壁ずり応力の意義の解明～新規内皮機能検査法を用いて

科学研究費助成事業基盤研究(C), 日本学術振興会, Apr, 2022 - Mar, 2025

大畑洋子, 細田公則, 冨田努, 中井陸運, 吉村壮平, 斎藤こずえ, 槇野久士
人工知能を用いた大規模脳卒中登録研究解析による治療方針決定補助と転帰予測

科学研究費助成事業基盤研究(C), 日本学術振興会, Apr, 2021 - Mar, 2024

吉村壮平, 古賀政利, 豊田一則, 中井陸運, 三輪佳織, 笹原祐介
超高齢化社会!! 本邦の脳血管病の発症と気象大気汚染の関係とそのかかる医療費

科学研究費助成事業基盤研究(C), 日本学術振興会, Apr, 2021 - Mar, 2024

米山喜平, 明石嘉浩, 樋熊拓未, 中井陸運
ビッグデータによる心筋梗塞の慢性期を含む新規医療の質指標の開発と国際共同比較研究

科学研究費助成事業基盤研究(C), 日本学術振興会, Apr, 2020 - Mar, 2023

中尾一泰, 安田聡, 野口暉夫, 中井陸運, 中尾葉子
Is a deteriorate in oral health the risk factor for metabolic syndrome? The Suita study

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

Ono Takahiro

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