論文

査読有り 最終著者 国際誌
2022年5月1日

Age-Related Recovery of Daily Living Activity After 1-Stage Complete Corpus Callosotomy: A Retrospective Analysis of 41 Cases.

Neurosurgery
  • Kazushi Ukishiro
  • ,
  • Shin-Ichiro Osawa
  • ,
  • Masaki Iwasaki
  • ,
  • Yosuke Kakisaka
  • ,
  • Kazutaka Jin
  • ,
  • Mitsugu Uematsu
  • ,
  • Tetsuya Yamamoto
  • ,
  • Teiji Tominaga
  • ,
  • Nobukazu Nakasato

90
5
開始ページ
547
終了ページ
551
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1227/neu.0000000000001871

BACKGROUND: Recovery time after corpus callosotomy (CC) is known to be longer in elderly than in younger patients. OBJECTIVE: To evaluate the relationship between patient age and recovery time of activities of daily living (ADL) after 1-stage complete CC. METHODS: This study included 41 patients (22 women; aged 13 months-34 years, median 7 years) who underwent 1-stage complete CC for medically intractable seizures with drop attacks, infantile spasms, and/or bilaterally synchronized electroencephalographic discharges between August 2009 and April 2019. The timing of restart of competence in 5 ADL categories and surgical outcomes were recorded. RESULTS: Patients (1) restarted speech at 2.2 ± 1.3 (mean ± 2 standard deviations; range 1-5) days, (2) restarted replying with their own name on request at 5.5 ± 8.6 (2-33) days, (3) restarted oral intake at 1.6 ± 1.7 (1-11) days, (5) discontinued intravenous feeding at 6.0 ± 3.0 (2-16) days, and (5) restarted ambulation or wheelchair movement at 5.8 ± 3.4 (2-10) days. Younger patients showed significantly (P < .0223) earlier recovery of ambulation or wheelchair movement, but no age difference was found in the other 4 ADL categories. Overall seizure freedom was achieved in 5 patients, excellent (>80%) seizure reduction in 11, good (50%-80%) seizure reduction in 5, and poor (<50%) seizure reduction in 20. CONCLUSION: Early ADL recovery after 1-stage complete CC is favorable in both young and adult patients. These findings, with good surgical outcomes, will encourage more positive consideration of 1-stage complete CC in both pediatric and adult patients.

リンク情報
DOI
https://doi.org/10.1227/neu.0000000000001871
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/35129138
Scopus
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85128493899&origin=inward
Scopus Citedby
https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85128493899&origin=inward
ID情報
  • DOI : 10.1227/neu.0000000000001871
  • eISSN : 1524-4040
  • PubMed ID : 35129138
  • SCOPUS ID : 85128493899

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