パラックパックニリアンマリーケリヘロ (Nirianne Marie Querijero Palacpac) - マイポータル

基本情報

所属: 大阪大学微生物病研究所特任教授（常勤）

学位: PhD(Osaka University)

J-GLOBAL ID: 201801011754906340
researchmap会員ID: B000311231

https://www.scopus.com/authid/detail.uri?authorId=6603009087

研究分野

ライフサイエンス / 感染症内科学 / Malaria research and clinical trials

論文

Plasmodium falciparum infection coinciding with the malaria vaccine candidate BK-SE36 administration interferes with the immune responses in Burkinabe children.

Alfred B Tiono, Nirianne Marie Q Palacpac, Edith Christiane Bougouma, Issa Nebie, Alphonse Ouédraogo, Sophie Houard, Nobuko Arisue, Flavia D'Alessio, Toshihiro Horii, Sodiomon B Sirima

Frontiers in immunology 14 1119820-1119820 2023年3月10日査読有り
Editorial: Puzzle pieces from malaria vaccine clinical trials.

Nirianne Marie Q Palacpac, Alfred B Tiono, Benjamin Mordmüller, Takafumi Tsuboi

Frontiers in immunology 14 1138763-1138763 2023年1月30日査読有り
African-specific polymorphisms in Plasmodium falciparum serine repeat antigen 5 in Uganda and Burkina Faso clinical samples do not interfere with antibody response to BK-SE36 vaccination.

Nobuko Arisue, Nirianne Marie Q Palacpac, Edward H Ntege, Adoke Yeka, Betty Balikagala, Bernard N Kanoi, Edith Christiane Bougouma, Alfred B Tiono, Issa Nebie, Amidou Diarra …

Frontiers in cellular and infection microbiology 12 1058081-1058081 2022年12月16日査読有り
The impact of sequestration on artemisinin-induced parasite clearance in Plasmodium falciparum malaria in Africa.

Naoyuki Fukuda, Betty Balikagala, Tsuyoshi Ueno, Denis A Anywar, Eisaku Kimura, Nirianne Marie Q Palacpac, Emmanuel I Odongo-Aginya, Martin Ogwang, Toshihiro Horii, Takashi Miida …

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 76(9) 1585-1593 2022年12月15日査読有り
Safety and immunogenicity of BK-SE36 in a blinded, randomized, controlled, age de-escalating phase Ib clinical trial in Burkinabe children.

Edith Christiane Bougouma, Nirianne Marie Q Palacpac, Alfred B Tiono, Issa Nebie, Alphonse Ouédraogo, Sophie Houard, Masanori Yagi, Sam Aboubacar Coulibaly, Amidou Diarra, Takahiro Tougan …

Frontiers in immunology 13 978591-978591 2022年8月1日査読有り
Meta-Analysis of Human Antibodies Against Plasmodium falciparum Variable Surface and Merozoite Stage Antigens.

Eizo Takashima, Bernard N Kanoi, Hikaru Nagaoka, Masayuki Morita, Ifra Hassan, Nirianne M Q Palacpac, Thomas G Egwang, Toshihiro Horii, Jesse Gitaka, Takafumi Tsuboi

Frontiers in immunology 13 887219-887219 2022年6月9日査読有り
Evidence of Artemisinin-Resistant Malaria in Africa

Betty Balikagala, Naoyuki Fukuda, Mie Ikeda, Osbert T. Katuro, Shin-Ichiro Tachibana, Masato Yamauchi, Walter Opio, Sakurako Emoto, Denis A. Anywar, Eisaku Kimura …

New England Journal of Medicine 385(13) 1163-1171 2021年9月23日
Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in Northern Uganda

Naoyuki Fukuda, Shin Ichiro Tachibana, Mie Ikeda, Miki Sakurai-Yatsushiro, Betty Balikagala, Osbert T. Katuro, Masato Yamauchi, Sakurako Emoto, Muneaki Hashimoto, Shouki Yatsushiro …

Parasitology International 81 2021年4月1日査読有り
Assessment of mixed plasmodium falciparum sera5 infection in endemic burkitt lymphoma: A case-control study in Malawi

Nobuko Arisue, George Chagaluka, Nirianne Marie Q. Palacpac, W. Thomas Johnston, Nora Mutalima, Sally Peprah, Kishor Bhatia, Eric Borgstein, George N. Liomba, Steve Kamiza …

Cancers 13(7) 2021年4月1日査読有り
Characterization of a Plasmodium falciparum PHISTc protein, PF3D7_0801000, in blood- stage malaria parasites

Hikaru Nagaoka, Bernard N. Kanoi, Masayuki Morita, Takahiro Nakata, Nirianne M.Q. Palacpac, Thomas G. Egwang, Toshihiro Horii, Takafumi Tsuboi, Eizo Takashima

Parasitology International 80 2021年2月1日査読有り
First-in-human randomised trial and follow-up study of Plasmodium falciparum blood-stage malaria vaccine BK-SE36 with CpG-ODN(K3)

Sachiko Ezoe, Nirianne Marie Q. Palacpac, Kohhei Tetsutani, Kouji Yamamoto, Kiyoshi Okada, Masaki Taira, Sumiyuki Nishida, Haruhiko Hirata, Atsushi Ogata, Tomomi Yamada …

Vaccine 38(46) 7246-7257 2020年10月27日査読有り
Global Repertoire of Human Antibodies Against Plasmodium falciparum RIFINs, SURFINs, and STEVORs in a Malaria Exposed Population

Bernard N. Kanoi, Hikaru Nagaoka, Michael T. White, Masayuki Morita, Nirianne M.Q. Palacpac, Edward H. Ntege, Betty Balikagala, Adoke Yeka, Thomas G. Egwang, Toshihiro Horii …

Frontiers in Immunology 11 2020年5月12日査読有り
Characteristic features of the SERA multigene family in the malaria parasite

Nobuko Arisue, Nirianne M.Q. Palacpac, Takahiro Tougan, Toshihiro Horii

Parasites and Vectors 13(1) 170-170 2020年4月査読有り
Recovery and stable persistence of chloroquine sensitivity in Plasmodium falciparum parasites after its discontinued use in Northern Uganda

Betty Balikagala, Miki Sakurai-Yatsushiro, Shin Ichiro Tachibana, Mie Ikeda, Masato Yamauchi, Osbert T. Katuro, Edward H. Ntege, Makoto Sekihara, Naoyuki Fukuda, Nobuyuki Takahashi …

Malaria Journal 19(1) 2020年2月18日査読有り
The N-Terminal Region of Plasmodium falciparum MSP10 Is a Target of Protective Antibodies in Malaria and Is Important for PfGAMA/PfMSP10 Interaction

Hikaru Nagaoka, Bernard N. Kanoi, Kana Jinoka, Masayuki Morita, Thangavelu U. Arumugam, Nirianne M.Q. Palacpac, Thomas G. Egwang, Toshihiro Horii, Takafumi Tsuboi, Eizo Takashima

Frontiers in Immunology 10 2019年11月20日査読有り
Comprehensive analysis of antibody responses to Plasmodium falciparum erythrocyte membrane protein 1 domains

Bernard N. Kanoi, Hikaru Nagaoka, Masayuki Morita, Michael T. White, Nirianne M.Q. Palacpac, Edward H. Ntege, Betty Balikagala, Adoke Yeka, Thomas G. Egwang, Toshihiro Horii …

Vaccine 36(45) 6826-6833 2018年10月29日査読有り
Artemisinin-resistant plasmodium falciparum with high survival rates, uganda, 2014-2016

Mie Ikeda, Megumi Kaneko, Shin Ichiro Tachibana, Betty Balikagala, Miki Sakurai-Yatsushiro, Shouki Yatsushiro, Nobuyuki Takahashi, Masato Yamauchi, Makoto Sekihara, Muneaki Hashimoto …

Emerging Infectious Diseases 24(4) 718-726 2018年4月1日査読有り
Corrigendum: Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

Fumiji Saito, Kouyuki Hirayasu, Takeshi Satoh, Christian W. Wang, John Lusingu, Takao Arimori, Kyoko Shida, Nirianne Marie Q. Palacpac, Sawako Itagaki, Shiroh Iwanaga …

Nature 554(7693) 554 2018年2月22日査読有り
Bifunctional activity of fused Plasmodium falciparum orotate phosphoribosyltransferase and orotidine 5′-monophosphate decarboxylase

Patsarawadee Paojinda, Waranya Imprasittichai, Sudaratana R. Krungkrai, Nirianne Marie Q. Palacpac, Toshihiro Horii, Jerapan Krungkrai

Parasitology International 67(1) 79-84 2018年2月1日査読有り
A possible origin population of pathogenic intestinal nematodes, Strongyloides stercoralis, unveiled by molecular phylogeny

Eiji Nagayasu, Myo Pa Pa Thet Hnin Htwe Aung, Thanaporn Hortiwakul, Akina Hino, Teruhisa Tanaka, Miwa Higashiarakawa, Alex Olia, Tomoyo Taniguchi, Soe Moe Thu Win, Isao Ohashi …

Scientific Reports 7(1) 2017年12月1日査読有り

もっとみる

MISC

Malaria vaccines: Facing unknowns

Nirianne Marie Q. Palacpac, Toshihiro Horii

F1000Research 9 2020年
Hematological and biochemical data obtained in rural Northern Uganda

Nirianne M.Q. Palacpac, Edward Ntege, Betty Balikagala, Adoke Yeka, Hiroki Shirai, Nahoko Suzuki, Christopher Nsereko, Bernard N. Kanoi, Takuya Okada, Thomas G. Egwang …

International Journal of Environmental Research and Public Health 11(5) 4870-4885 2014年5月6日
Risk of Burkitt Lymphoma Correlates with Breadth and Strength of Antibody Response to Plasmodium Falciparum Malaria Stage-Specific Antigens

Peter Aka, Maria Vila, Amar Jariwala, Francis Nkrumah, Benjamin Emmanuel, Masanory Yagi, Nirianne Palacpac, Maria Periago, Janet Neequaye, Christine Kiruthu …

BLOOD 120(21) 2012年11月
Plasmodium falciparum serine repeat antigen 5 (SE36) as a malaria vaccine candidate

Nirianne Marie Q. Palacpac, Nobuko Arisue, Takahiro Tougan, Ken J. Ishii, Toshihiro Horii

Vaccine 29(35) 5837-5845 2011年8月11日
Lipid metabolism in Plasmodium falciparum-infected erythrocytes: Possible new targets for malaria chemotherapy

Toshihide Mitamura, Nirianne Marie Q. Palacpac

Microbes and Infection 5(6) 545-552 2003年5月

講演・口頭発表等

SERA5による分子カモフラージュとワクチン開発

堀井俊宏, 東岸任弘, PALACPAC NIRIANNE MARIE QUERIJERO

第26回分子寄生虫学ワークショップ／第16回分子寄生虫・マラリア研究フォーラム合同大会
Immune response to the malaria vaccine candidate BK-SE36 in clinical trials

N Palacpac, S Sirima, O Leroy and T Horii

ICOPA2018
Vaccine development of BK-SE36: based on 47-kDa N-terminal domain of SERA 5.

Palacpac Nirianne Marie Q., Tohihiro Horii

Gordon Research Conference
Do not forget the blood-stage: BK-SE36/CpG in Clinical Trial

Toshihiro Horii

Keystone symposia Conference: Malaria: From Innovation to Eradication (B5)
マラリアワクチン開発とマラリア制圧

堀井俊宏

第32回日本環境感染学会総会・学術集会
Uniqueness of the blood-stage malaria vaccine candidate BK-SE36

Toshihiro Horii

U.S.-Japan Cooperative Medical Sciences Program (USJCMSP), 19th International Conference on Emerging Infectious Diseases in the Pacific Rim, Parasitic Disease Panel
Development and Sustainability of Malaria Vaccine Clinical Research Center in Uganda and Clinical Development of BK-SE36 Malaria Vaccine Candidate

堀井俊宏, Palacpac Nirianne M.Q., 木村英作

TICADプレイベント：第三回国際合同シンポジウム“日アフリカ科学技術イノベーション協力の推進に向けて”(TICAD Pre-event; The 3rd International symposium for the Promotion of Science and Technology Innovation Cooperation between Africa and Japan.)
BK-SE36 malaria vaccine candidate for young children

Toshihiro Horii

Symposium for Promotion of science and technology cooperation between Africa and Japan and Symposium for Innovate Network for Pan-African Surveillance of NTD and Infectious Diseases Program
Clinical Development of BK-SE36 malaria vaccine

Toshihiro Horii

The 56th Annual Meeting for the Japanese Society of Tropical Medicine
Immune evasion of Plasmodium falciparum via paired inhibitory receptor

Fumiji Saito, Takeshi Satoh, Tadahiro Suenaga, Nirianne M. Q. Palacpac, Kouyuki Hirayasu, Shiroh Iwanaga, Toshihiro Horii, Hisashi Arase

第2回国際シンポジウム・第4回マトリョーシカ型生物学研究会招待有り
BK-SE36 malaria vaccine candidate for young children

Toshihiro Horii

Malaria R&D in a Time of Global Partnerships 招待有り
An Integrative approach to BK-SE36 malaria vaccine development in Uganda

Toshihiro Horii

An Integrated Approach to Tackling Malaria in Africa Conference
NO ALLELE SPECIFIC IMMUNE RESPONSE TO PLASMODIUM FALCIPARUM SERA5 IN BK-SE36 VACCINES THAT EXPERIENCED MALARIA INFECTION DURING THE FOLLOW-UP STUDY OF A MALARIA VACCINE TRIAL.

Nobuko Arisue, Nirianne M. Q. Palacpac, Masanori Yagi, Takahiro Tougan, Hiroki Shirai ,Betty Balikagala, Adoke Yeka, Edward Ntege, Bernard Kanoi, Katuro Osbert, Tom Egwang, Toshihiro Horii

17th Annual Conference Asia-Pacific International Molecular Biology Network (A-IMBN)
HLA gene polymorphism in Ugandan population that participated in the Phase 1b trial of BK-SE36

Takahiro Tougan, Nirianne Q. Palacpac, Masanori Yagi, Thomas G Egwang, Toshihiro Horii

17th A-IMBN Conference
マラリアワクチンBK-SE36に対する抗体応答と感染・発症防御効果の解析

八木正典、Nirianne M. Q. Palacpac、東岸任弘、伊藤一弥、Betty Balikagala、Edward Ntege、Adoke Yeka、Bernard N. Kanoi、Osbert Katuro、白井宏樹、福島若葉、廣田良夫、Thomas G. Egwang、堀井俊宏

第83回日本寄生虫学会大会
SE36 マラリアワクチン抗原遺伝子sera5の多型解析

有末伸子, Nirianne M. Q. Palacpac, 八木正典, 東岸任弘, Betty Balikagala, Adoke Yeka, Edward Ntege, Bernard Kanoi, Katuro Osbert, Tom Egwang, 堀井俊宏

第11回分子寄生虫マラリア研究フォーラム
熱帯熱マラリア原虫SERA5のN末端反復配列は天然変性の特徴をもつ防御エピトープである

八木正典、Gilles Bang、有末伸子、東岸任弘、Nirianne M.Q. Palacpac、青枝大貴、石井健、Thomas G. Egwang、Pierre Druilhe、堀井俊宏

第11回分子寄生虫マラリア研究フォーラム
A blood-stage vaccine clinical trial and follow-up study in Uganda: The promise of BK-SE36

Nirianne Marie Q. Palacpac, Edward Ntege, Betty Balikagala, Adoke Yeka, Nahoko Suzuki, Hiroki Shirai, Kazuya Ito, Masanori Yagi, Christopher Nsereko, Bernard Kanoi, Takuya Okada, Kohhei Tetsutani, Wakaba Fukushima, Yoshio Hirota, Nobuko Arisue, Sawako Itagaki and Toshihiro Horii

The 12th Awaji International Forum on Infection and Immunity
African HLA genes in a population that participated in the Phase 1b trial of BK-SE36

Takahiro Tougan, Nirianne Q. Palacpac, Masanori Yagi, Thomas G Egwang and Toshihiro Horii

The 12th Awaji International Forum on Infection and Immunity
No allele specific immune response to Plasmodium falciparum SERA5 in participants that experienced malaria infection during the BK-SE36 malaria vaccine trial.

Nobuko Arisue, Nirianne M. Q. Palacpac, Masanori Yagi, Takahiro Tougan, Betty Balikagala Adoke Yeka, Edward Ntege, Bernard Kanoi, Katuro Osbert, Tom Egwang and Toshihiro Horii

The 12th Awaji International Forum on Infection and Immunity

もっとみる

所属学協会

日本寄生虫学会

メディア報道

阪大など開発のマラリアワクチン、西アフリカで治験5月から

日本経済新聞 2017年3月