2011年12月
Rh-Catalyzed Ortho-Selective C-H Borylatiob of N-Functionalized Arenes with Silica-Supported Bridgehead Monophosphine Ligands
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- 巻
- 133
- 号
- 48
- 開始ページ
- 19310
- 終了ページ
- 19313
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1021/ja208364a
- 出版者・発行元
- AMER CHEMICAL SOC
Supported phosphine-Rh systems, prepared in situ from silica-supported bridgehead monophosphines and [Rh(OH)(cod)]2, have enabled ortho-selective C-H borylation for a range of arenes containing nitrogen-based directing groups. The regioselectivity was excellent with various N-directing groups, including saturated and unsaturated N-heterocycles, tert-aminoalkyl groups, and iminetype C-N double bonds. The reaction showed significant tolerance toward steric repulsion around the reacting C-H bond. This Rh catalysis complements the Jr-catalyzed orthoborylation, which is effective for arenes with oxygen-based directing groups.
- リンク情報
- ID情報
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- DOI : 10.1021/ja208364a
- ISSN : 0002-7863
- eISSN : 1520-5126
- ORCIDのPut Code : 28783527
- Web of Science ID : WOS:000297606500014