J-GLOBAL         Last updated: Dec 12, 2018 at 03:49
Gifu University
Faculty of Engineering


Capillaryliquid chromatography/Miniaturization of separation columns has been investigated in liquid chromatography (LC) for more than a quarter century. Advantages of capillary columns in LC are attributed to narrow column diameter and low eluent flow rate. Development of capillary columns with much higher efficiency than conventional LC columns will shift users from conventional to capillary LC, as seen in the development of capillary GC. Columns with highercolumn efficiency must have higher permeability in comparison with common densely packed columns. Open tubular capillary columns and monolithic columns are expected to achieve higher column efficiency because of their higher permeability. At this moment, monolithic silica columns can be one of candidates for such a highly permeable separation system. Capillary LC will save energy and wastes. It will also improve column efficiency of LC and facilitate hyphenation with MS, leading to acquirement of more accurate analytical results in the very near future./Ion chromatography/1. Development of capillary ion chromatography2. Development of novel stationary phases for ion chromatography3. Peak parking technique for ion chromatography4. Separation of anions and cations with a single IC system

Research Areas


Academic & Professional Experience

Professor, Gifu University Faculty of Engineering, Department of Chemistry
Research Associate, Nagoya University,
Fac. of Eng.
Associate Professor, Nagoya University,
Research Center for Resource and Energy


Applied Chemistry, Graduate School, Division of Engineering, Nagoya University
Faculty of Engineering, Nagoya University
Applied Chemistry, Graduate School, Division of Engineering, Nagoya University

Awards & Honors

May 2012
Giorgio Nota Award, 36th International Symposium on Capillary Chromatography

Published Papers

TAKEUCHI Toyohide, Lee Wah Lim
Analytical Sciences   26 937-941   Sep 2010   [Refereed]
Analtytical Sciences   29(4) 423-427   Apr 2013   [Refereed]
CHROMATOGRAPHY   30(2) 55-56   Aug 2009


Toyohide Takeuchi
Journal of Chromatography Library   70 229-241   Dec 2005
Pre-column derivatization of amino acids with 5-dimethylaminonaphthalene-1-sulfonyl chloride (dansyl chloride) or 4-dimethylaminoazobenzene-4′-sulfonyl chloride (dabsyl chloride) is described. These pre-column derivatization methods enable a sensi...
Jiye Jin, Yasutada Suzuki, Naoyoshi Ishikawa, Toyohide Takeuchi
Analytical Sciences   20 205-207   Jan 2004
The present study was aimed at developing a portable miniaturized FIA system with a two-electrode based amperometric detector for on-site monitoring of residual chlorine in environmental samples. The electrode potential control and current data co...
Stephen A. Wise, Kiyokatsu Jinno, Toyohide Takeuchi
Analytical and Bioanalytical Chemistry   382 533-534
Safni, Toyohide Takeuchi, Tomoo Miwa
Journal of Chromatography B: Biomedical Sciences and Applications   753 409-412
Microcolumn ion chromatography using anion exchangers modified with dextran sulfate has been applied to the determination of alkali and alkaline-earth metal ions contained in guinea pig serum and bovine serum. These serums contained Na+, NH4 +, K+...
Kazutoku Ohta, Atsuya Towata, Masayoshi Ohashi, Toyohide Takeuchi
Journal of Chromatography A   1039 161-169
The application of unfunctionized polymethacrylate resin (TSKgel G3000PWXL) as a stationary phase in liquid chromatography with UV detection for C1-C7 aliphatic monocarboxylic acids (formic acid, acetic acid, propionic acid, butyric acid, isovaler...

Books etc

Indirect Conductimetric Detection of Nonelectrolytes in Microcolumn Liquid Chromatography
Chromatographia   1993   
HPLC of amino acids as dansyl anddabsyl derivatives: Quantitation of Amino Acids and Amines by Chromatography
Takeuchi Toyohide(Gifu University)
Feb 2001   
Let's Start ケミストリー
Feb 2004   
Aug 2004   

Teaching Experience


Research Grants & Projects

Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2008 - 2010    Investigator(s): Toyohide TAKEUCHI
Hydrodynamic chromatography (HDC) conditions have been examined for the separation of silica colloids with 5-78 nm diameters. Conventional HPLC columns with 25 cm×4.6 mm I.D. were prepared and employed for HDC.Interstitial spaces among packing mat...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2004 - 2005    Investigator(s): Toyohide TAKEUCHI
1. Monolithic silica capillary columns dynamically modified with quaternary ammonium ions were evaluated for the determination of bromide in seawater samples. A quaternary ammonium ion such as cetyltrimethylammonium was dynamically introduced onto...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 1998 - 2000    Investigator(s): Toyohide TAKEUCHI
Retention behavior of analyte ions on silica-based anion exchangers modified with anionic polysaccharides such as mucopolysaccharides and dextran sulfate has been investisated in ion chromatography. The anion-exchange capacity of the substrate was...
Capillary chromatography
Project Year: 1980