2013年4月4日
PH-sensitive DNA cleaving agents: In situ activation by ring contraction of benzo-fused cyclobutanols
Chemical Communications
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- ,
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- 巻
- 49
- 号
- 26
- 開始ページ
- 2622
- 終了ページ
- 2624
- 記述言語
- 英語
- 掲載種別
- 研究論文（学術雑誌）
- DOI
- 10.1039/c3cc39246e
Benzo-fused cyclobutanols were developed as novel DNA cleaving molecules. The molecules nick a strand of supercoiled DNA under acidic conditions. By contrast, almost no activity was observed under neutral or basic conditions.© The Royal Society of Chemistry 2013.
- ID情報
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- DOI : 10.1039/c3cc39246e
- ISSN : 1359-7345
- ISSN : 1364-548X
- PubMed ID : 23435647
- SCOPUS ID : 84874829533