Matsuura Shinya


Matsuura Shinya

J-GLOBAL         Last updated: Dec 7, 2019 at 03:22
 
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Name
Matsuura Shinya
E-mail
shinyahiroshima-u.ac.jp
Affiliation
Hiroshima University
Section
.
Job title
教授
Degree
Doctor of Medicine(Yamaguchi University)
Research funding number
90274133
ORCID ID
0000-0001-5294-081X

Research Areas

 
 

Academic & Professional Experience

 
Apr 1990
 - 
Mar 1991
Medical Staff, Yamaguchi University Hospital
 
Apr 1991
 - 
Mar 1993
Fellow, Japan Society for the Promotion of Science for Japanese Junior Scientists
 
Aug 1993
 - 
Jul 1995
Visiting Scientist, St. Marys Hospital medical School, University of London
 
Aug 1995
 - 
Mar 1999
Research associate, RIRBM, Hiroshima University
 
Apr 1999
 - 
Jul 2002
Assistant professor, RIRBM, Hiroshima University
 
Aug 2002
   
 
Professor, RIRBM, Hiroshima University
 

Education

 
Apr 1979
 - 
Mar 1985
Faculty of Medicine, Yamaguchi University
 
Apr 1986
 - 
Mar 1990
Graduate School, Division of Medicine, Yamaguchi University
 

Published Papers

 
Miyamoto, Tatsuo;Matsuura, Shinya
ONCOTARGET   6(28) 24582-24583   2015   [Refereed][Invited]
Porazinski, Sean; Wang, Huijia; Asaoka, Yoichi; Behrndt, Martin; Miyamoto, Tatsuo; Morita, Hitoshi; Hata, Shoji; Sasaki, Takashi; Krens, S. F. Gabriel; Osada, Yumi et al.
NATURE   521(7551) 217-+   May 2015   [Refereed]
Vertebrates have a unique 3D body shape in which correct tissue and organ shape and alignment are essential for function. For example, vision requires the lens to be centred in the eye cup which must in turn be correctly positioned in the head(1)....
Miyamoto, Tatsuo; Hosoba, Kosuke; Ochiai, Hiroshi; Royba, Ekaterina; Izumi, Hideki; Sakuma, Tetsushi; Yamamoto, Takashi; Dynlacht, Brian David; Matsuura, Shinya
CELL REPORTS   10(5) 664-673   Feb 2015   [Refereed]
The primary cilium is an antenna-like, microtubule-based organelle on the surface of most vertebrate cells for receiving extracellular information. Although primary cilia form in the quiescent phase, ciliary disassembly occurs when quiescent cells...
Ochiai, Hiroshi; Miyamoto, Tatsuo; Kanai, Akinori; Hosoba, Kosuke; Sakuma, Tetsushi; Kudo, Yoshiki; Asami, Keiko; Ogawa, Atsushi; Watanabe, Akihiro; Kajii, Tadashi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   111(4) 1461-1466   Jan 2014   [Refereed]
Cancer-prone syndrome of premature chromatid separation with mosaic variegated aneuploidy [PCS (MVA) syndrome] is a rare autosomal recessive disorder characterized by constitutional aneuploidy and a high risk of childhood cancer. We previously rep...
Miyamoto, Ryosuke; Morino, Hiroyuki; Yoshizawa, Akio; Miyazaki, Yoshimichi; Maruyama, Hirofumi; Murakami, Nagahisa; Fukada, Kei; Izumi, Yuishin; Matsuura, Shinya; Kaji, Ryuji et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES   337(1-2) 219-223   Feb 2014   [Refereed]
Progressive myoclonic ataxia (PMA) is a clinical syndrome defined as progressive ataxia and myoclonus and infrequent seizures in the absence of progressive dementia. Due to the extremely heterogeneous nature of PMA, a large proportion of PMA cases...
Sakuma, Tetsushi; Ochiai, Hiroshi; Kaneko, Takehito; Mashimo, Tomoji; Tokumasu, Daisuke; Sakane, Yuto; Suzuki, Ken-ichi; Miyamoto, Tatsuo; Sakamoto, Naoaki; Matsuura, Shinya et al.
SCIENTIFIC REPORTS   3    Nov 2013   [Refereed]
Transcription activator-like effector (TALE) nuclease (TALEN) is a site-specific nuclease, which can be freely designed and easily constructed. Numerous methods of constructing TALENs harboring different TALE scaffolds and repeat variants have rec...
Sakuma, Tetsushi; Hosoi, Sayaka; Woltjen, Knut; Suzuki, Ken-ichi; Kashiwagi, Keiko; Wada, Housei; Ochiai, Hiroshi; Miyamoto, Tatsuo; Kawai, Narudo; Sasakura, Yasunori et al.
GENES TO CELLS   18(4) 315-326   Apr 2013   [Refereed]
Transcription activatorlike effector nucleases (TALENs) have recently arisen as effective tools for targeted genome engineering. Here, we report streamlined methods for the construction and evaluation of TALENs based on the Golden Gate TALEN and T...
Ochiai, Hiroshi; Sakamoto, Naoaki; Fujita, Kazumasa; Nishikawa, Masatoshi; Suzuki, Ken-ichi; Matsuura, Shinya; Miyamoto, Tatsuo; Sakuma, Tetsushi; Shibata, Tatsuo; Yamamoto, Takashi
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   109(27) 10915-10920   Jul 2012   [Refereed]
To understand complex biological systems, such as the development of multicellular organisms, it is important to characterize the gene expression dynamics. However, there is currently no universal technique for targeted insertion of reporter genes...
Kobayashi, Junya; Fujimoto, Hiroko; Sato, Jun; Hayashi, Ikue; Burma, Sandeep; Matsuura, Shinya; Chen, David J.; Komatsu, Kenshi
PLOS ONE   7(11)    Nov 2012   [Refereed]
H2AX is an important factor for chromatin remodeling to facilitate accumulation of DNA damage-related proteins at DNA double-strand break (DSB) sites. In order to further understand the role of H2AX in the DNA damage response (DDR), we attempted t...
Miyamoto, Tatsuo; Porazinski, Sean; Wang, Huijia; Borovina, Antonia; Ciruna, Brian; Shimizu, Atsushi; Kajii, Tadashi; Kikuchi, Akira; Furutani-Seiki, Makoto; Matsuura, Shinya
HUMAN MOLECULAR GENETICS   20(10) 2058-2070   May 2011   [Refereed]
Budding uninhibited by benzimidazole-related 1 (BUBR1) is a central molecule of the spindle assembly checkpoint. Germline mutations in the budding uninhibited by benzimidazoles 1 homolog beta gene encoding BUBR1 cause premature chromatid separatio...
Matsumoto, Yoshiyuki; Miyamoto, Tatsuo; Sakamoto, Hiromi; Izumi, Hideki; Nakazawa, Yuka; Ogi, Tomoo; Tahara, Hidetoshi; Oku, Shozo; Hiramoto, Azuma; Shiiki, Toshihide et al.
DNA REPAIR   10(3) 314-321   Mar 2011   [Refereed]
MRE11 and NBS1 function together as components of a MRE11/RAD5O/NBS1 protein complex, however deficiency of either protein does not result in the same clinical features. Mutations in the NBN gene underlie Nijmegen breakage syndrome (NBS), a chromo...
Yanagihara, Hiromi; Kobayashi, Junya; Tateishi, Satoshi; Kato, Akihiro; Matsuura, Shinya; Tauchi, Hiroshi; Yamada, Kouichi; Takezawa, Jun; Sugasawa, Kaoru; Masutani, Chikahide et al.
MOLECULAR CELL   43(5) 788-797   Sep 2011   [Refereed]
Translesion DNA synthesis, a process orchestrated by monoubiquitinated PCNA, is critical for DNA damage tolerance. While the ubiquitin-conjugating enzyme RAD6 and ubiquitin ligase RAD18 are known to monoubiquitinate PCNA, how they are regulated by...
Fujita Kazumasa;Takechi Eriko;Sakamoto Naoaki;Sumiyoshi Noriko;Izumi Shunsuke;Miyamoto Tatsuo;Matsuura Shinya;Tsurugaya Toko;Akasaka Koji;Yamamoto Takashi
Mechanisms of development   127(3-4) 235-245   2010   [Refereed]
:Cell surface heparan sulfate proteoglycans (HSPGs) play significant roles in the regulation of developmental signaling, including vascular endothelial growth factor (VEGF), fibroblast growth factor, Wnt and bone morphogenetic protein signaling, t...
Kanemoto, Nobuko; Fukushima, Takashi; Imoto, Natsuki; Koike, Kazutoshi; Kanemoto, Katsuyoshi; Matsuura, Shinya
PEDIATRICS INTERNATIONAL   52(1) 141-142   Feb 2010   [Refereed]
Maruyama, Hirofumi; Morino, Hiroyuki; Ito, Hidefumi; Izumi, Yuishin; Kato, Hidemasa; Watanabe, Yasuhito; Kinoshita, Yoshimi; Kamada, Masaki; Nodera, Hiroyuki; Suzuki, Hidenori et al.
NATURE   465(7295) 223-U109   May 2010   [Refereed]
Amyotrophic lateral sclerosis (ALS) has its onset in middle age and is a progressive disorder characterized by degeneration of motor neurons of the primary motor cortex, brainstem and spinal cord(1). Most cases of ALS are sporadic, but about 10% a...
Kobayashi, Junya; Okui, Michiyo; Asaithamby, Aroumougame; Burma, Sandeep; Chen, Benjamin P. C.; Tanimoto, Keiji; Matsuura, Shinya; Komatsu, Kenshi; Chen, David J.
MECHANISMS OF AGEING AND DEVELOPMENT   131(6) 436-444   Jun 2010   [Refereed]
Werner syndrome (WS), caused by mutation of the WRN gene, is an autosomal recessive disorder associated with premature aging and predisposition to cancer WRN belongs to the RecQ DNA helicase family, members of which play a role in maintaining geno...
Kobayashi, Junya; Tauchi, Hiroshi; Chen, Benjamin; Bruma, Sandeep; Tashiro, Satoshi; Matsuura, Shinya; Tanimoto, Keiji; Chen, David J.; Komatsu, Kenshi
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   380(4) 752-757   Mar 2009   [Refereed]
Phosphorylated histone H2AX (gamma-H2AX) functions in the recruitment of DNA damage response Proteins to DNA double-strand breaks (DSBs) and facilitates DSB repair. ATM also co-localizes with gamma-H2AX at DSB sites following its auto-phosphorylat...
Izumi, H.; Matsumoto, Y.; Ikeuchi, T.; Saya, H.; Kajii, T.; Matsuura, S.
ONCOGENE   28(31) 2806-2820   Aug 2009   [Refereed]
BubR1 is a critical component of the mitotic checkpoint that delays the onset of anaphase until all chromosomes have established bipolar attachment to the microtubules. We previously reported that mutations of the BUB1B gene ( encoding BubR1) caus...
Uehara, Yoshihiko; Ikehata, Hironobu; Komura, Jun-ichro; Ito, Ari; Ogata, Masaki; Itoh, Tsunetoshi; Hirayama, Ryoichi; Furusawa, Yoshiya; Ando, Koichi; Paunesku, Tatjana et al.
RADIATION RESEARCH   170(2) 216-223   Aug 2008   [Refereed]
With the goal of understanding the role of non-homologous end-joining repair in the maintenance of genetic information at the tissue level, we studied mutations induced by radiation and subsequent repair of DNA double-strand breaks in Ku70 gene-de...
Iijima, Kenta; Muranaka, Chizuko; Kobayashi, Junya; Sakamoto, Shuichi; Komatsu, Kenshi; Matsuura, Shinya; Kubota, Nobuo; Tauchi, Hiroshi
DNA REPAIR   7(10) 1705-1716   Oct 2008   [Refereed]
DNA damage induced apoptosis, along with precise DNA damage repair, is a critical cellular function, and both of these functions are necessary for cancer prevention. The NBS1 protein is known to be a key regulator of DNA damage repair. It acts by ...
Haruta, Masayuki; Matsumoto, Yoshiyuki; Izumi, Hideki; Watanabe, Naoki; Fukuzawa, Masahiro; Matsuura, Shinya; Kaneko, Yasuhiko
MOLECULAR CARCINOGENESIS   47(9) 660-666   Sep 2008   [Refereed]
BUB1B and RASSF1A genes play specific roles in the mitotic checkpoint, and their defects may cause chromosome instability or aneuploidy in mouse fibroblasts and human cancer cell lines, however, few studies have reported a correlation between defe...
Saito, T.; Hama, S.; Izumi, H.; Yamasaki, F.; Kajiwara, Y.; Matsuura, S.; Morishima, K.; Hidaka, T.; Shrestha, P.; Sugiyama, K. et al.
BRITISH JOURNAL OF CANCER   98(2) 345-355   Jan 2008   [Refereed]
Glioblastoma is characterised by invasive growth and a high degree of radioresistance. Survivin, a regulator of chromosome segregation, is highly expressed and known to induce radioresistance in human gliomas. In this study, we examined the effect...
Antoccia, A.; Sakamoto, S.; Matsuura, S.; Tauchi, H.; Komatsu, K.
RADIATION RESEARCH   170(3) 345-352   Sep 2008   [Refereed]
Nijmegen breakage syndrome shares several common cellular features with ataxia telangiectasia, including chromosomal instability and aberrant S- and G(2)-phase checkpoint regulation. We show here that after irradiation, NBS1 interacts physically w...
Sakamoto, S.; Iijima, K.; Mochizuki, D.; Nakamura, K.; Teshigawara, K.; Kobayashi, J.; Matsuura, S.; Tauchi, H.; Komatsu, K.
ONCOGENE   26(41) 6002-6009   Sep 2007   [Refereed]
The proteins responsible for radiation sensitive disorders, NBS1, kinase ataxia- telangiectasia-( A- T)- mutated ( ATM) and MRE11, interact through the C- terminus of NBS1 in response to the generation of DNA double- strand breaks ( DSBs) and are ...
Morishima, Ken-ichi; Sakamoto, Shuichi; Kobayashi, Junya; Izumi, Hideki; Suda, Tetsuji; Matsumoto, Yoshiyuki; Tauchi, Hiroshi; Ide, Hiroshi; Komatsu, Kenshi; Matsuura, Shinya
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   362(4) 872-879   Nov 2007   [Refereed]
TopBP1 is involved in DNA replication and DNA damage checkpoint. Recent studies have demonstrated that TopBP1 is a direct positive effecter of ATR. However, it is not known how TopBP1 recognizes damaged DNA. Here, we show that TopBP1 formed nuclea...
Matsuura, S; Matsumoto, Y; Morishima, K; Izumi, H; Matsumoto, H; Ito, E; Tsutsui, K; Kobayashi, J; Tauchi, H; Kajiwara, Y et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A   140A(4) 358-367   Feb 2006   [Refereed]
Cancer-prone syndrome of premature chromatid separation (PCS syndrome) with mosaic variegated aneuploidy (MVA) is a rare autosomal recessive disorder characterized by growth retardation, microcephaly, childhood cancer, premature chromatid separati...
Arifin, MT; Hama, S; Kajiwara, Y; Sugiyama, K; Saito, T; Matsuura, S; Yamasaki, F; Arita, K; Kurisu, K
JOURNAL OF NEURO-ONCOLOGY   77(3) 273-277   May 2006   [Refereed]
Background: The negative consequences of the cytoplasmic localization of p16 in patients with high-grade astrocytomas, on their prognosis, was investigated. Methods: p16 Expression was examined in 20 anaplastic astrocytoma and 42 glioblastoma pati...
Matsumoto, Y; Morishima, K; Honda, A; Watabe, S; Yamamoto, M; Hara, M; Hasui, M; Saito, C; Takayanagi, T; Yamanaka, T et al.
JOURNAL OF HUMAN GENETICS   50(7) 353-356   Jul 2005   [Refereed]
Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive malformation syndrome characterized by microcephaly, syndactyly of toes, ambiguous genitalia, and mental retardation. The underlying DHCR7 gene has been identified and a wide variety of d...
Kobayashi, J; Antoccia, A; Tauchi, H; Matsuura, S; Komatsu, K
DNA REPAIR   3(8-9) 855-861   2004   [Refereed]
Nijmegen breakage syndrome is a recessive genetic disorder, characterized by elevated sensitivity to ionizing radiation, chromosome instability and high frequency of malignancies. Since cellular features partly overlap with those of ataxia-telangi...
Nijmegen breakage syndrome and DNA double strand break repair by NBS1 complex
Matsuura S, Kobayashi J, Tauchi H, Komatsu K
Advances in Biophysics   38 65-80   Apr 2004
Iijima, K; Komatsu, K; Matsuura, S; Tauchi, H
CHROMOSOMA   113(2) 53-61   Sep 2004   [Refereed]
NBS1 is the key regulator of the RAD50/ MRE11/NBS1 (R/M/N) protein complex, a sensor and mediator for cellular DNA damage response. NBS1 potentiates the enzymatic activity of MRE11 and directs the R/M/N complex to sites of DNA damage, where it for...
Hama, S; Matsuura, S; Tauchi, H; Yamasaki, F; Kajiwara, Y; Arita, K; Yoshioka, H; Heike, Y; Mandai, K; Kurisu, K
BRITISH JOURNAL OF CANCER   89(9) 1802-1811   Nov 2003   [Refereed]
It is well established that cells synchronised at the G1 - S phase are highly radiosensitive. In this study, p16-null human glioma cell lines were induced into G1 cell cycle arrest by adenovirus-mediated p16 gene transfer, and examined for radiati...
Tauchi, H; Matsuura, S; Kobayashi, J; Sakamoto, S; Komatsu, K
ONCOGENE   21(58) 8967-8980   Dec 2002   [Refereed]
DNA double-strand breaks represent the most potentially serious damage to a genome and hence, at least two pathways of DNA repair have evolved; namely, homologous recombination repair and non-homologous end joining. Defects in both rejoining proce...
Kobayashi, J; Tauchi, H; Sakamoto, S; Nakamura, A; Morishima, K; Matsuura, S; Kobayashi, T; Tamai, K; Tanimoto, K; Komatsu, K
CURRENT BIOLOGY   12(21) 1846-1851   Oct 2002   [Refereed]
DNA double-strand breaks represent the most potentially serious damage to a genome; hence, many repair proteins are recruited to nuclear damage sites by as yet poorly characterized sensor mechanisms. Here, we show that NBS1, the gene product defec...
Tauchi, H; Kobayashi, J; Morishima, K; van Gent, DC; Shiraishi, T; Verkaik, NS; vanHeems, D; Ito, E; Nakamura, A; Sonodo, E et al.
NATURE   420(6911) 93-98   Nov 2002   [Refereed]
Double-strand breaks occur during DNA replication and are also induced by ionizing radiation. There are at least two pathways which can repair such breaks: non-homologous end joining and homologous recombination (HR). Although these pathways are e...
Nijmegen breakage syndrome gene, NBS1, and molecular links to factors for genome stability.
Tauchi H, Matsuura S, Kobayashi J, Sakamoto S, Komatsu K
Oncogene   21 8967-8980   Apr 2002
Studies of mutagenesis caused by low dose rate tritium radiation using a novel hyper-sensitive detection system
Tauchi, H; Ichimasa, M; Ichimasa, Y; Shiraishi, T; Morishima, K; Matsuura, S; Komatsu, K
FUSION SCIENCE AND TECHNOLOGY   41(3) 413-416   May 2002   [Refereed]
A novel hyper-sensitive detection system was developed to detect Hprt-deficient mutations using Hprt deficient hamster fibroblast cells which carry a normal human X-chromosome. The system has been found to be 100-fold more sensitive for detecting ...
The forkhead-associated domain of NBS1 is essential for nuclear foci formation after irradiation but not essential for hRAD50 center dot hMRE11 center dot NBS1 complex DNA repair activity
Tauchi, H; Kobayashi, J; Morishima, K; Matsuura, S; Nakamura, A; Shiraishi, T; Ito, E; Masnada, D; Delia, D; Komatsu, K
JOURNAL OF BIOLOGICAL CHEMISTRY   276(1) 12-15   Jan 2001   [Refereed]
NBS1 (p95), the protein responsible for Nijmegen breakage syndrome, shows a weak homology to the yeast Xrs2 protein at the N terminus region, known as the forkhead-associated (FHA) domain and the BRCA1 C terminus domain. The protein interacts with...
Yamada, M; Matsuura, S; Tsukahara, M; Ebe, K; Ohtsu, M; Furuta, H; Kobayashi, I; Kawamura, N; Okano, M; Shouji, R et al.
AMERICAN JOURNAL OF MEDICAL GENETICS   100(1) 9-12   Apr 2001   [Refereed]
We report on an 11-year-old Japanese girl with combined immunodeficiency and chromosomal instability. She had postnatal growth deficiency and microcephaly, preaxial polydactyly of the left hand, and susceptibility to infections, Immunological stud...
Comparative genomic hybridization analysis suggests a gain of chromosome 7p associated with lymph node metastasis in non-small cell lung cancer
Ubagai, T; Matsuura, S; Tauchi, H; Itou, K; Komatsu, K
ONCOLOGY REPORTS   8(1) 83-88   2001   [Refereed]
We analyzed the chromosomal gains and losses that occur in 30 non-small cell lung carcinomas by comparative genomic hybridization. Their chromosomal imbalances showed histological type-specific patterns in adenocarcinomas and in squamous cell carc...
Ishikawa, S; Ishikawa, M; Tokuda, T; Yoshida, K; Wakui, K; Matsuura, S; Ohara, S; Sekijima, Y; Hidaka, E; Fukushima, Y et al.
AMERICAN JOURNAL OF MEDICAL GENETICS   94(4) 265-270   Oct 2000   [Refereed]
We report on a Japanese family having an autosomal dominant neurodegenerative disease with chromosomal instability and radiosensitivity. Clinical manifestations of affected members included short stature, osteoporosis, severe dental caries, and va...
Matsuura, S; Ito, E; Tauchi, H; Komatsu, K; Ikeuchi, T; Kajii, T
AMERICAN JOURNAL OF HUMAN GENETICS   67(2) 483-486   Aug 2000   [Refereed]
Skin fibroblast cells from two unrelated male infants with a chromosome-instability disorder were analyzed for their response to colcemid-induced mitotic-spindle checkpoint. The infants both had severe growth and developmental retardation, microce...
Absence of mutations in the NBS1 gene in B-cell malignant lymphoma patients
Hama, S; Matsuura, S; Tauchi, H; Sawada, J; Kato, C; Yamasaki, F; Yoshioka, H; Sugiyama, K; Arita, K; Kurisu, K et al.
ANTICANCER RESEARCH   20(3B) 1897-1900   2000   [Refereed]
Background: Nijmegen breakage syndrome (NBS), also known as ataxia-telangiectasia (AT) variant, is an autosomal recessive disorder characterized by microcephaly, growth retardation severe combined immunodeficiency and a high incidence of lymphoid ...
Nijmegen breakage syndrome
Hiel, JA; Weemaes, CM; van den Heuvel, LP; van Engelen, BG; Gabreels, FJ; Smeets, DF; van der Burgt, I; Chrzanovska, KH; Bernatowska, E; Krajewska-Walasek, M et al.
ARCHIVES OF DISEASE IN CHILDHOOD   82(5) 400-406   May 2000   [Refereed]
Background-Nijmegen breakage syndrome (NBS) is a rare autosomal recessive disorder. NBS-1, the gene defective in NBS, is located on chromosome 8q21 and has recently been cloned. The gene product, nibrin, is a novel protein, which is member of the ...
Cell cycle and LET dependence for radiation-induced mutation: possible mechanism for reversed dose-rate effect.
J. Rad. Res.   40 45-52   Apr 2000
Neutron Generator (HIRRAC) and Dosimetry study.
Endo S, Hoshi M, Takada J, Tauchi H, Matsuura S, Takeoka S , Kitagawa K, Suga S, Komatsu K.
J. Rad. Res.   40 14-20   Apr 1999
A polymorphic CA repeat marker at the human 27-kD calbindin (CALB1) locus.
Morishima K, Matsuura S, Tauchi H, Nakamura A, Komatsu K
J. Hum. Genet.   44 414-415   Apr 1999
Four novel mutations of the Fanconi anemia group A gene (FAA) in Japanese patients.
Nakamura A, Matsuura S, Tauchi H, Hanada R, Ohashi H, Hasegawa T, Honda K, Masuno M, Imaizumi K, Sugita K, Ide T, Komatsu K.
J. Hum. Genet.   44 48-51   Apr 1999
Sequence analysis of an 800-kb genomic DNA region on chromosome 8q21, which contains the Nijmegen breakage syndrome, NBS1.
Tauchi H, Matsuura S, Isomura M, Kinjo T, Nakamura A, Sakamoto S, Kondo N, Endo S, Komatsu K, Nakamura Y.
Genomics   55 242-247   Apr 1999
Expression of Full-Length NBS1 Protein Restors Normal Radiation Responses in Cells from Nijmegen Breakage Syndrome Patients
Ito A, Tauchi H, Kobayashi J, Morishima K, Nakamura A, Hirokawa Y, Matsuura S, Ito K, Komatsu K.
Biochemical and Biophysical Reseach Communications   265 716-721   Jun 1999   [Refereed]

Books etc

 
Nijmegen Breakage Syndrome and Functions of the Responsible Protein, NBS1. Volff J-N (ed): Genome and Disease.
Karger   Jun 2006   ISBN:3805580290

Conference Activities & Talks

 
Analysis of individual differences in radiosensitivity using genome editing  [Invited]
Shinya Matsuura, Ekaterina Royba, Silvia Natsuko Akutsu, Hiromi Yanagihara, Hiroshi Ochiai, Yoshiki Kudo, Satoshi Tashiro, Tatsuo Miyamoto
3rd International Symposium on the System of Radiological Protection, ICRP2015   Oct 2015   International Commission of Radiological Protection
1) Gene and function in microcephaly. 2) Mosaic Variegated Aneuploidy (Premature Chromatid Separation) Syndrome. [Invited]
Shinya Matsuura
Oct 2010   
PCS (MVA) SYNDROME AND DUAL ROLES OF BUBR1 [Invited]
Shinya Matsuura
25th RBC International Symposium “Genomic Instability: mechanisms and diseases”   Nov 2009   
Genetic characterization of a patient with a progeroid phenotype and mosaic variegated aneuploidy
Harumi Fujita, Takashi Sasaki, Tatsuo Miyamoto, Takehiko Mori, Kazuhiko Nakabayashi, Kenichiro Hata, Shinya Matsuura, Yoichi Matsubara, Masayuki Amagai, Akiharu Kubo
KEYSTONE SYMPOSIA MEETING, Aging and Mechanism of Aging-Related Disease   15 May 2017   
Inflammatory response in primary human endothelial cells subjected to acute or protracted gamma irradiation
Elena Zaharieva, Hidehiko Kawai, Toshiya Inaba, Shinya Matsuura, Kenji Kamiya
4 Jun 2017   

Research Grants & Projects

 
Ministry of Education Culture Sports Science and Technology: The Center of World Intelligence Project for Nuclear S&T and Human Resource Development
Project Year: Apr 2015 - Mar 2016
Project Year: 2015 - 2017
Project Year: 2015 - 2016
Ministry of Education, Culture, Sports, Science and Technology: The Initiatives for Atomic Energy Basic and Generic Strategic Research
Project Year: Sep 2014 - Mar 2015
Project Year: 2013 - 2014