OSADA Satoshi

J-GLOBAL         Last updated: Jul 6, 2016 at 18:04
OSADA Satoshi
Saga University
Courses of Science and Engineering
Job title
Accociate Professor
Doctor (Science)(Kyushu University)

Research Areas


Academic & Professional Experience

Stanford University, Visiting Scholar


Graduate School, Division of Natural Science, Kyushu University
Faculty of Science, Kyushu University


Torao Suga, Satoshi Osada, Takayuki Narita, Yushi Oishi, Hiroaki Kodama
Materials Science and Engineering C   47 345-350   Feb 2015
© 2014 Elsevier B.V. All rights reserved.Hydrogels formed by low-molecular hydrogelators have been used as anti-microbial agents and cell-attachment materials. However the biomedical application of low-molecular gelators is slowly progressing comp...
Ryo Hayashi, Toshiki Kitajima, Hikaru Mizuguchi, Miki Fujimoto, Aya Yamaguchi, Shuichiro Koga, Yuya Koga, Satoshi Osada, Hiroaki Kodama
Bioorganic and Medicinal Chemistry   22 3824-3828   Aug 2014
While stimulation of formyl peptide receptors (FPRs) on the surface of human neutrophils induces several immune responses, under conditions of continuous activation of the receptor by agonists such as formyl-Met-Leu-Phe-OH (fMLP), neutrophil-depen...
Ryo Hayashi, Kazuhiro Nakatsui, Daisuke Sugiyama, Toshiki Kitajima, Nobuhiko Oohara, Masashi Sugiya, Satoshi Osada, Hiroaki Kodama
Journal of Inorganic Biochemistry   137 109-114   Jan 2014
We found that Au(I) complexed with 2,3-bis(tert-butyl(methyl)phosphino) quinoxaline (10) was a potent anti-tumor agent (half-maximal growth inhibitory concentration, GI50 = 0.87 μM) with broad anti-tumor activity. In particular, the activity of co...
Yoshiro Chuman, Mariko Ueyama, Satoshi Sano, Fei Wu, Yuhei Kiyota, Takayoshi Higashi, Satoshi Osada, Kazuyasu Sakaguchi
Chemistry Letters   42 833-835   Aug 2013
Histone deacetylase (HDAC) inhibitors belong to a new class of potential anticancer agents. It may be possible to reduce some of the toxicity by specifically targeting only the HDAC isoform. Here, stereoisomeric HDAC inhibitors containing fluoroal...
Ryo Hayashi, Masaya Miyazaki, Masaya Miyazaki, Satoshi Osada, Hiroshi Kawasaki, Ichiro Fujita, Yuhei Hamasaki, Hiroaki Kodama
Bioorganic and Medicinal Chemistry   21 668-675   Feb 2013
Formyl-Met-Leu-Phe-OH (fMLP) binds to formyl peptide receptors, FPR1 and FPR2, and evokes migration and superoxide anion production in human neutrophils. To obtain a more effective and selective ligand, fMLP analogs in which the Phe residue was su...

Books etc

Activation of Human Neutrophils by fMLP Analogs Containing 2,3-Cyclopropane Amino Acid(共著)
Peptide Chemistry 1996   1997   
Receptor Specificity of [2,3-Cyclopropane Amino Acids]-fMLP Analogs (共著)
Peptides- Frontiers of Peptide Science   1999   
Effect of enviroment on the stability of helical Aib-model peptides (共著)
Peptides Science ミ Present and Future   1999   
Synthesis and Conformational Studies of Cyclic Peptides Containing the C-terminal Tripeptide Sequence of Oxytocin (共著)
Peptide Science 1998   1999   
Photoaffinity Labeling of Formylpeptide Receptors by fMLP Analogs (共著)
Peptides Science 2001   2002   

Research Grants & Projects

Synthesis of fluorine-containing amino acids and their peptides
Synthesis of unnatural amino acids.