木下朝博 (Tomohiro Kinoshita) - マイポータル

基本情報

所属: 旧所属名古屋大学大学院医学系研究科分子総合医学専攻准教授

学位: 医学博士(名古屋大学)

J-GLOBAL ID: 200901095821027925
researchmap会員ID: 1000251718

研究キーワード

研究分野

委員歴

MISC

119

Prognostic factors for mature natural killer (NK) cell neoplasms: aggressive NK cell leukemia and extranodal NK cell lymphoma, nasal type

R. Suzuki, J. Suzumiya, M. Yamaguchi, S. Nakamura, J. Kameoka, H. Kojima, M. Abe, T. Kinoshita, T. Yoshino, K. Iwatsuki …

ANNALS OF ONCOLOGY 21(5) 1032-1040 2010年5月
Aberrant DNA methylation of the p57KIP2 gene is a sensitive biomarker for detecting minimal residual disease in diffuse large B cell lymphoma

Kazumi Hagiwara, Yinghua Li, Tomohiro Kinoshita, Shinji Kunishma, Haruhiko Ohashi, Tomomitsu Hotta, Hirokazu Nagai

LEUKEMIA RESEARCH 34(1) 50-54 2010年1月
Escape mechanisms from antibody therapy to lymphoma cells: Downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation

Takumi Sugimoto, Akihiro Tomita, Junji Hiraga, Kazuyuki Shimada, Hitoshi Kiyoi, Tomohiro Kinoshita, Tomoki Naoe

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 390(1) 48-53 2009年12月
Phase I/II Study of Concurrent Chemoradiotherapy for Localized Nasal Natural Killer/T-Cell Lymphoma: Japan Clinical Oncology Group Study JCOG0211

Motoko Yamaguchi, Kensei Tobinai, Masahiko Oguchi, Naoki Ishizuka, Yukio Kobayashi, Yasushi Isobe, Kenichi Ishizawa, Nobuo Maseki, Kuniaki Itoh, Noriko Usui …

JOURNAL OF CLINICAL ONCOLOGY 27(33) 5594-5600 2009年11月
Presentation and management of intravascular large B-cell lymphoma

Kazuyuki Shimada, Tomohiro Kinoshita, Tomoki Naoe, Shigeo Nakamura

LANCET ONCOLOGY 10(9) 895-902 2009年9月
Presentation and management of intravascular large B-cell lymphoma

Kazuyuki Shimada, Tomohiro Kinoshita, Tomoki Naoe, Shigeo Nakamura

The Lancet Oncology 10(9) 895-902 2009年9月
Down-regulation of CD20 expression in B-cell lymphoma cells after treatment with rituximab-containing combination chemotherapies: its prevalence and clinical significance

Junji Hiraga, Akihiro Tomita, Takumi Sugimoto, Kazuyuki Shimada, Masafumi Ito, Shigeo Nakamura, Hitoshi Kiyoi, Tomohiro Kinoshita, Tomoki Naoe

BLOOD 113(20) 4885-4893 2009年5月
Combinations of cytogenetics and international scoring system can predict poor prognosis in multiple myeloma after high-dose chemotherapy and autologous stem cell transplantation

Yoshihiro Inamoto, Shingo Kurahashi, Nobuhiko Imahashi, Nobuaki Fukushima, Tatsuya Adachi, Tomohiro Kinoshita, Keitaro Tsushita, Koichi Miyamura, Tomoki Naoe, Isamu Sugiura

AMERICAN JOURNAL OF HEMATOLOGY 84(5) 283-286 2009年5月
Age-related Epstein-Barr virus (EBV)-associated B-cell lymphoproliferative disorders: comparison with EBV-positive classic Hodgkin lymphoma in elderly patients

Naoko Asano, Kazuhito Yamamoto, Jun-Ichi Tamaru, Takashi Oyama, Fumihiro Ishida, Koichi Ohshima, Tadashi Yoshino, Naoya Nakamura, Shigeo Mori, Osamu Yoshie …

BLOOD 113(12) 2629-2636 2009年3月
Evaluation of organ involvement in intravascular large B-cell lymphoma by F-18-fluorodeoxyglucose positron emission tomography

Kazuyuki Shimada, Hiroshi Kosugi, Satoko Shimada, Hiroto Narimatsu, Yoshitsugu Koyama, Nobuaki Suzuki, Masaaki Yuge, Hironori Nishibori, Yosuke Iwata, Shigeo Nakamura …

INTERNATIONAL JOURNAL OF HEMATOLOGY 88(2) 149-153 2008年9月
Retrospective analysis of intravascular large B-cell lymphoma treated with rituximab-containing chemotherapy as reported by the IVL study group in Japan

Kazuyuki Shimada, Kosei Matsue, Kazuhito Yamamoto, Takuhei Murase, Naoaki Ichikawa, Masataka Okamoto, Nozomi Niitsu, Hiroshi Kosugi, Norifumi Tsukamoto, Hiroshi Miwa …

JOURNAL OF CLINICAL ONCOLOGY 26(19) 3189-3195 2008年7月
Age-related Epstein-Barr virus-associated B-cell lymphoproliferative disorders: Special references to lymphomas surrounding this newly recognized clinicopathologic disease

Yoshie Shimoyama, Kazuhito Yamamoto, Naoko Asano, Takashi Oyama, Tomohiro Kinoshita, Shigeo Nakamura

CANCER SCIENCE 99(6) 1085-1091 2008年6月
Clinical significance of nuclear non-phosphorylated beta-catenin in acute myeloid leukaemia and myelodysplastic syndrome

Jinglan Xu, Momoko Suzuki, Yousuke Niwa, Junji Hiraga, Tetsuro Nagasaka, Masafumi Ito, Shigeo Nakamura, Akihiro Tomita, Akihiro Abe, Hitoshi Kiyoi …

BRITISH JOURNAL OF HAEMATOLOGY 140(4) 394-401 2008年2月
Sustained remission after rituximab-containing chemotherapy for intravascular large B-cell lymphoma

SHIMADA Kazuyuki, SHIMADA Kazuyuki, KOSUGI Hiroshi, NARIMATSU Hiroto, SHIMADA Satoko, SUZUKI Tatsuya, SUZUKI Tatsuya, ITO Masafumi, KINOSHITA Tomohiro, MORI Naoyoshi …

J Clin Exp Hematop 48(1) 25-28 2008年
Sustained Remission after Rituximab-containing Chemotherapy for Intravascular Large B-cell Lymphoma

SHIMADA Kazuyuki, KOSUGI Hiroshi, NARIMATSU Hiroto, SHIMADA Satoko, SUZUKI Tatsuya, ITO Masafumi, KINOSHITA Tomohiro, MORI Naoyoshi, NAOE Tomoki

Journal of clinical and experimental hematopathology 48(1) 25-28 2008年
Age-related EBV-Associated B-Cell Lymphoproliferative disorders constitute a distinct clinicopathologic group: A study of 96 patients

Takashi Oyama, Kazuhito Yamamoto, Naoko Asano, Aya Oshiro, Ritsuro Suzuki, Yoshitoyo Kagami, Yasuo Morishima, Kengo Takeuchi, Toshiyuki Izumo, Shigeo Mori …

CLINICAL CANCER RESEARCH 13(17) 5124-5132 2007年9月
Prognostic analysis of aberrant somatic hypermutation of RhoH gene in diffuse large B cell lymphoma

J. Hiraga, A. Katsumi, T. Iwasaki, A. Abe, H. Kiyoi, T. Matsushita, T. Kinoshita, T. Naoe

LEUKEMIA 21(8) 1846-1847 2007年8月
Epigenetic regulation of CD20 protein expression in a novel B-Cell lymphoma cell line, RRBL1, established from a patient treated repeatedly with rituximab-containing chemotherapy

Akihiro Tomita, Junji Hiraga, Hitoshi Kiyoi, Manabu Ninomiya, Takumi Sugimoto, Masafumi Ito, Tomohiro Kinoshita, Tomoki Naoe

INTERNATIONAL JOURNAL OF HEMATOLOGY 86(1) 49-57 2007年7月
Intravascular large B-cell lymphoma: the heterogeneous clinical manifestations of its classical and hemophagocytosis-related forms

Shigeo Nakamura, Takuhei Murase, Tomohiro Kinoshita

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 92(4) 434-436 2007年4月
Successful umbilical cord blood transplantation using a reduced-intensity preparative regimen without total body irradiation and tacrolimus plus methotrexate for prophylaxis of graft-versus-host disease in a patient with adult T-cell leukemia/lymphoma

Hiroto Narimatsu, Makoto Murata, Kyoko Sugimoto, Seitaro Terakura, Tomohiro Kinoshita, Tomoki Naoe

LEUKEMIA & LYMPHOMA 48(4) 841-843 2007年

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書籍等出版物

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所属学協会

Works(作品等)

悪性リンパ腫に対する最適化されたモノクローナル抗体併用療法の開発による標準的治療法の確立

2010年 - 2012年
再発・難治性骨髄腫に対する至適分子標的療法の確立と生物学的治療予測因子の探索

2009年 - 2011年
分子基盤に基づく難治性リンパ系腫瘍の診断及び治療法の開発に関する研究

2009年 - 2010年
リンパ系腫瘍に対する標準的治療確立のための多施設共同研究

2008年 - 2010年
リツキシマブ＋ステロイド併用悪性リンパ腫治療中のB型肝炎ウイルス再活性化への対策に関する研究

2008年 - 2010年
リツキシマブ治療における腫瘍側の生物学的作用機序の解明と感受性増強療法の開発

2008年 - 2010年

共同研究・競争的資金等の研究課題

分子基盤に基づく難治性リンパ系腫瘍の診断及び治療法の開発に関する研究

厚生労働科学研究費補助金 2007年 - 2008年
造血器腫瘍の分子病態

2000年
Molecular biology of Hematological malignancies.

2000年
造血器腫瘍の化学療法
Chemotherapy of hematological malignancies