Nov, 2007
Synthesis, structure and thermal stability of fully hydrophobic porphyrin-DNA conjugates
TETRAHEDRON LETTERS
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- Volume
- 48
- Number
- 48
- First page
- 8514
- Last page
- 8517
- Language
- English
- Publishing type
- DOI
- 10.1016/j.tetlet.2007.09.147
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
The DNAs modified with tetraphenyl porphyrin at the center of 13mer oligonucleotide were synthesized using phosphoramidite chemistry and automated DNA synthesis. When the porphyrin modified oligonucleotide was annealed with its complementary strand, they formed a standard B-form duplex. The porphyrin moiety intercalated in the duplex, and moderately lowered the thermal stability. (C) 2007 Elsevier Ltd. All rights reserved.
- Link information
- ID information
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- DOI : 10.1016/j.tetlet.2007.09.147
- ISSN : 0040-4039
- CiNii Articles ID : 80018129397
- Web of Science ID : WOS:000251621900027