Misc.

Nov, 2007

Synthesis, structure and thermal stability of fully hydrophobic porphyrin-DNA conjugates

TETRAHEDRON LETTERS
  • Takashi Murashima
  • ,
  • Kazuyuki Hayata
  • ,
  • Yumi Saiki
  • ,
  • Jun Matsui
  • ,
  • Daisuke Miyoshi
  • ,
  • Takashi Yamada
  • ,
  • Toshifumi Miyazawa
  • ,
  • Naoki Sugimoto

Volume
48
Number
48
First page
8514
Last page
8517
Language
English
Publishing type
DOI
10.1016/j.tetlet.2007.09.147
Publisher
PERGAMON-ELSEVIER SCIENCE LTD

The DNAs modified with tetraphenyl porphyrin at the center of 13mer oligonucleotide were synthesized using phosphoramidite chemistry and automated DNA synthesis. When the porphyrin modified oligonucleotide was annealed with its complementary strand, they formed a standard B-form duplex. The porphyrin moiety intercalated in the duplex, and moderately lowered the thermal stability. (C) 2007 Elsevier Ltd. All rights reserved.

Link information
DOI
https://doi.org/10.1016/j.tetlet.2007.09.147
CiNii Articles
http://ci.nii.ac.jp/naid/80018129397
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000251621900027&DestApp=WOS_CPL
ID information
  • DOI : 10.1016/j.tetlet.2007.09.147
  • ISSN : 0040-4039
  • CiNii Articles ID : 80018129397
  • Web of Science ID : WOS:000251621900027

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