論文

査読有り
2016年8月

Eosinophilic pustular folliculitis: A published work-based comprehensive analysis of therapeutic responsiveness

JOURNAL OF DERMATOLOGY
  • Takashi Nomura
  • ,
  • Mayumi Katoh
  • ,
  • Yosuke Yamamoto
  • ,
  • Yoshiki Miyachi
  • ,
  • Kenji Kabashima

43
8
開始ページ
919
終了ページ
927
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1111/1346-8138.13287
出版者・発行元
WILEY-BLACKWELL

Eosinophilic pustular folliculitis (EPF) is a non-infectious inflammatory dermatosis of unknown etiology that principally affects the hair follicles. There are three variants of EPF: (i) classic EPF; (ii) immunosuppression-associated EPF, which is subdivided into HIV-associated (IS/HIV) and non-HIV-associated (IS/non-HIV); and (iii) infancy-associated EPF. Oral indomethacin is efficacious, especially for classic EPF. No comprehensive information on the efficacies of other medical management regimens is currently available. In this study, we surveyed regimens for EPF that were described in articles published between 1965 and 2013. In total, there were 1171 regimens; 874, 137, 45 and 115 of which were applied to classic, IS/HIV, IS/non-HIV and infancy-associated EPF, respectively. Classic EPF was preferentially treated with oral indomethacin with efficacy of 84% whereas topical steroids were preferred for IS/HIV, IS/non-HIV and infancy-associated EPF with efficacy of 47%, 73% and 82%, respectively. Other regimens such as oral Sairei-to (a Chinese-Japanese herbal medicine), diaminodiphenyl sulfone, cyclosporin and topical tacrolimus were effective for indomethacin-resistant cases. Although the preclusion of direct comparison among cases was one limitation, this study provides a dataset that is applicable to the construction of therapeutic algorithms for EPF.

リンク情報
DOI
https://doi.org/10.1111/1346-8138.13287
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000380922800009&DestApp=WOS_CPL
ID情報
  • DOI : 10.1111/1346-8138.13287
  • ISSN : 0385-2407
  • eISSN : 1346-8138
  • Web of Science ID : WOS:000380922800009

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