2002年10月
Histological examination of beta-tricalcium phosphate graft in human femur
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
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- 巻
- 63
- 号
- 5
- 開始ページ
- 601
- 終了ページ
- 604
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1002/jbm.10380
- 出版者・発行元
- JOHN WILEY & SONS INC
Prominent osteoconductive activity and the biodegradable nature of beta tricalcium phosphate (beta-TCP) for bone grafts in animal experiments has been reported. A new type of beta-TCP has been manufactured at extraordinarily high purity and has been available as potent bone grafting substitute for clinical use. The histological features of grafted beta-TCP in human bone have been analyzed. A 33-year-old female with a bone tumor of the proximal femur underwent curettage and beta-TCP graft under the diagnosis of probable benign fibrous dysplasia. Four weeks later, the proximal femur, including the grafted beta-TCP was resected because of the final diagnosis of the curettaged materials was osteosarcoma. The resected specimen revealed abundant direct new bone apposition on beta-TCP. There was no cartilaginous tissue or enchondral ossification. Bone formation was more prominent in the periphery of the grafted area than in the center. There was a considerable number of osteoclast-like giant cells surrounding the beta-TCP. This case illustrated that highly purified beta-TCP had prominent osteoconductive activity and biodegradable nature in human bone. (C) 2002 Wiley Periodicals, Inc.
- リンク情報
- ID情報
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- DOI : 10.1002/jbm.10380
- ISSN : 0021-9304
- PubMed ID : 12209906
- Web of Science ID : WOS:000178159600019