TORII Motomi

J-GLOBAL         Last updated: Dec 27, 2018 at 11:53
TORII Motomi
Ehime University
Proteo-Science Center Division of Molecular Parasitology
Job title
Professor,Associate Dean of Graduate School,Departmental Dean,Associate Director of the Center
Doctor (Medicine)(Ehime University)

Research Areas


Academic & Professional Experience

Apr 2013
Professor, Proteo-Science Center, Ehime University
Apr 1995
Mar 2013
Professor, School of Medicine, Ehime University
Jul 1991
Mar 1995
Associate Professor, School of Medicine, Ehime University
Dec 1990
Jun 1991
Lecturer, School of Medicine, Ehime University
Apr 1983
Dec 1990
Instructor, School of Medicine, Ehime University


Apr 1979
Mar 1983
Doctor course, Graduate School of Medicine, Ehime University
Graduate School, Division of Medicine, Ehime University
Oct 1973
Mar 1979
School of Medicine, Ehime University
Faculty of Medicine, Ehime University

Committee Memberships

Japanease society of Parasitology  
Japanese Society of Tropical Medicine  
Japanease society of Parasitology  

Published Papers

Oda-Yokouchi Y, Tachibana M, Iriko H, Torii M, Ishino T, Tsuboi T
Parasitology international   68(1) 17-23   Feb 2019   [Refereed]
Ishino T, Murata E, Tokunaga N, Baba M, Tachibana M, Thongkukiatkul A, Tsuboi T, Torii M
Cellular microbiology   21(1) e12964   Jan 2019   [Refereed]
Jenwithisuk R, Kangwanrangsan N, Tachibana M, Thongkukiatkul A, Otsuki H, Sattabongkot J, Tsuboi T, Torii M, Ishino T
Malaria journal   17(1) 466   Dec 2018   [Refereed]
Tohmoto T, Takashima E, Takeo S, Morita M, Nagaoka H, Udomsangpetch R, Sattabongkot J, Ishino T, Torii M, Tsuboi T
Parasitology international   69 25-29   Oct 2018   [Refereed]
Iriko H, Ishino T, Otsuki H, Ito D, Tachibana M, Torii M, Tsuboi T
Parasitology international   67(5) 637-639   Jun 2018   [Refereed]
Morita M, Nagaoka H, Ntege EH, Kanoi BN, Ito D, Nakata T, Lee JW, Tokunaga K, Iimura T, Torii M, Tsuboi T, Takashima E
Scientific reports   8(1) 3696   Feb 2018   [Refereed]
Arredondo SA, Swearingen KE, Martinson T, Steel R, Dankwa DA, Harupa A, Camargo N, Betz W, Vigdorovich V, Oliver BG, Kangwanrangsan N, Ishino T, Sather N, Mikolajczak S, Vaughan AM, Torii M, Moritz RL, Kappe SHI
Frontiers in cellular and infection microbiology   8 413   2018   [Refereed]
Morita M, Takashima E, Ito D, Miura K, Thongkukiatkul A, Diouf A, Fairhurst RM, Diakite M, Long CA, Torii M, Tsuboi T
Scientific reports   7 46086   Apr 2017   [Refereed]
Hitoshi Otsuki, Hitoshi Otsuki, Yuki Yokouchi, Natsumi Iyoku, Mayumi Tachibana, Takafumi Tsuboi, Motomi Torii
Parasitology International   64(4) 60-63   Aug 2015   [Refereed]
© 2015 Elsevier Ireland Ltd. Rodent malaria is a useful model for evaluating the efficacy of malaria vaccine candidates; however, labor-intensive microscopic parasite counting hampers the use of an in vivo parasite challenge in high-throughput scr...
Mayumi Tachibana, Nantavadee Suwanabun, Osamu Kaneko, Hideyuki Iriko, Hitoshi Otsuki, Jetsumon Sattabongkot, Jetsumon Sattabongkot, Akira Kaneko, Akira Kaneko, Socrates Herrera, Motomi Torii, Takafumi Tsuboi
Vaccine   33(16) 1901-1908   Jan 2015   [Refereed]
© 2015 Elsevier Ltd. Malaria transmission-blocking vaccines (TBV) aim to interfere with the development of the malaria parasite in the mosquito vector, and thus prevent spread of transmission in a community. To date three TBV candidates have been ...
Takeshi Arakawa, Takafumi Tsuboi, Jetsumon Sattabongkot, Kozue Sakao, Motomi Torii, Takeshi Miyata
Clinical and Vaccine Immunology   21(4) 561-569   Jan 2014   [Refereed]
The development of malaria vaccines is challenging, partly because the immunogenicity of recombinant malaria parasite antigens is low. We previously demonstrated that parasite antigens integrated into a tricomponent immunopotentiating complex incr...
Anke Harupa, Anke Harupa, Brandon K. Sack, Viswanathan Lakshmanan, Nadia Arang, Alyse N. Douglass, Brian G. Oliver, Andrew B. Stuart, D. Noah Sather, Scott E. Lindner, Scott E. Lindner, Kevin Hybiske, Motomi Torii, Stefan H I Kappe, Stefan H I Kappe
Infection and Immunity   82(11) 4643-4653   Jan 2014   [Refereed]
© 2014, American Society for Microbiology. Plasmodium sporozoites develop within oocysts in the mosquito midgut wall and then migrate to the salivary glands. After transmission, they embark on a complex journey to the mammalian liver, where they i...
Satoko Itani, Motomi Torii, Motomi Torii, Tomoko Ishino, Tomoko Ishino
Parasitology International   63(4) 584-590   Jan 2014   [Refereed]
The course of malaria infection in mammals begins with transmission of Plasmodium sporozoites into the skin by Anopheles mosquitoes, followed by migration of the sporozoites to the liver. As no symptoms present until hepatic merozoites are release...
Thangavelu U. Arumugam, Daisuke Ito, Daisuke Ito, Eizo Takashima, Mayumi Tachibana, Tomoko Ishino, Motomi Torii, Takafumi Tsuboi, Takafumi Tsuboi
Expert Review of Vaccines   13(1) 75-85   Jan 2014   [Refereed]
Malaria causes about 216 million clinical cases and 0.7 million deaths annually. One promising route to address malaria is vaccination. However, so far, not even a single licensed malaria vaccine has been developed. Even the effectiveness of RTS,S...
Daisuke Ito, Tomoyuki Hasegawa, Kazutoyo Miura, Tsutomu Yamasaki, Tsutomu Yamasaki, Thangavelu U. Arumugam, Amporn Thongkukiatkul, Satoru Takeo, Satoru Takeo, Eizo Takashima, Jetsumon Sattabongkot, Eun Taek Han, Carole A. Long, Motomi Torii, Takafumi Tsuboia, Takafumi Tsuboia
Infection and Immunity   81(11) 4289-4298   Nov 2013   [Refereed]
Erythrocyte invasion by merozoites is an obligatory stage of Plasmodium infection and is essential to disease progression. Proteins in the apical organelles of merozoites mediate the invasion of erythrocytes and are potential malaria vaccine candi...
Ying Pei, Jessica L. Miller, Scott E. Lindner, Ashley M. Vaughan, Motomi Torii, Stefan H I Kappe, Stefan H I Kappe
Cellular Microbiology   15(9) 1508-1526   Sep 2013   [Refereed]
Summary: Plasmodium falciparum (Pf) blood stages express falstatin, an inhibitor of cysteine proteases (ICP), which is implicated in regulating proteolysis during red blood cell infection. Recent data using the Plasmodium berghei rodent malaria mo...
Jack S. Richards, Jack S. Richards, Jack S. Richards, Jack S. Richards, Thangavelu U. Arumugam, Linda Reiling, Julie Healer, Anthony N. Hodder, Freya J I Fowkes, Freya J I Fowkes, Freya J I Fowkes, Nadia Cross, Christine Langer, Satoru Takeo, Alex D. Uboldi, Jennifer K. Thompson, Paul R. Gilson, Ross L. Coppel, Peter M. Siba, Christopher L. King, Motomi Torii, Chetan E. Chitnis, David L. Narum, Ivo Mueller, Ivo Mueller, Brendan S. Crabb, Alan F. Cowman, Alan F. Cowman, Takafumi Tsuboi, James G. Beeson, James G. Beeson, James G. Beeson
Journal of Immunology   191(2) 795-809   Jul 2013   [Refereed]
The development of effective malaria vaccines and immune biomarkers of malaria is a high priority for malaria control and elimination. Ags expressed by merozoites of Plasmodium falciparum are likely to be important targets of human immunity and ar...
Naoaki Shinzawa, Tomoko Ishino, Mayumi Tachibana, Takafumi Tsuboi, Motomi Torii
PLoS ONE   8(5) e63753   May 2013   [Refereed]
Anopheline mosquitoes are the major vectors of human malaria. Parasite-mosquito interactions are a critical aspect of disease transmission and a potential target for malaria control. Current investigations into parasite-mosquito interactions frequ...
Niwat Kangwanrangsan, Niwat Kangwanrangsan, Mayumi Tachibana, Mayumi Tachibana, Rachaneeporn Jenwithisuk, Rachaneeporn Jenwithisuk, Takafumi Tsuboi, Suda Riengrojpitak, Motomi Torii, Motomi Torii, Tomoko Ishino, Tomoko Ishino
Malaria Journal   12(1) 129   Apr 2013   [Refereed]
Background: Despite the development of malaria control programs, billions of people are still at risk for this infectious disease. Recently, the idea of the transmission-blocking vaccine, which works by interrupting the infection of mosquitoes by ...
Jian Li, Jian Li, Daisuke Ito, Jun Hu Chen, Jun Hu Chen, Feng Lu, Feng Lu, Yang Cheng, Bo Wang, Kwon Soo Ha, Jun Cao, Jun Cao, Motomi Torii, Jetsumon Sattabongkot, Takafumi Tsuboi, Eun Taek Han
Parasitology International   61(3) 443-449   Sep 2012   [Refereed]
Pf12 in Plasmodium falciparum has been characterized as a merozoite surface protein and the Pf12 gene is actively transcribed during schizont stage. An orthologous gene, Pv12, has been identified in genome of P. vivax, but the protein product has ...
Morakot Kaewthamasorn, Morakot Kaewthamasorn, Kazuhide Yahata, Jean Semé Fils Alexandre, Jean Semé Fils Alexandre, Phonepadith Xangsayarath, Shusuke Nakazawa, Motomi Torii, Jetsumon Sattabongkot, Jetsumon Sattabongkot, Rachanee Udomsangpetch, Osamu Kaneko
Parasitology International   61(2) 317-323   Jun 2012   [Refereed]
Plasmodium falciparum SURFIN4.2 (PFD1160w) is a polymorphic protein expressed on the surface of parasite-infected erythrocytes. Such molecules are expected to be under strong host immune pressure, thus we analyzed the nucleotide diversity of the N...
Hayley E. Bullen, Hayley E. Bullen, Sarah C. Charnaud, Sarah C. Charnaud, Ming Kalanon, David T. Riglar, David T. Riglar, Chaitali Dekiwadia, Niwat Kangwanrangsan, Motomi Torii, Takafumi Tsuboi, Jacob Baum, Stuart A. Ralph, Alan F. Cowman, Tania F. De Koning-Ward, Brendan S. Crabb, Brendan S. Crabb, Brendan S. Crabb, Paul R. Gilsona, Paul R. Gilsona
Journal of Biological Chemistry   287(11) 7871-7884   Mar 2012   [Refereed]
To survive within its host erythrocyte, Plasmodium falciparum must export hundreds of proteins across both its parasite plasma membrane and surrounding parasitophorous vacuole membrane, most of which are likely to use a protein complex known as PT...
Mayumi Tachibana, Chiho Sato, Hitoshi Otsuki, Jetsumon Sattabongkot, Jetsumon Sattabongkot, Osamu Kaneko, Motomi Torii, Motomi Torii, Takafumi Tsuboi, Takafumi Tsuboi, Takafumi Tsuboi
Vaccine   30(10) 1807-1812   Feb 2012   [Refereed]
The malaria transmission-blocking vaccine (TBV) aims to interfere the development of malaria parasite in the mosquito and prevent further transmission in the community. So far only two TBV candidates have been identified in Plasmodium vivax; ookin...
Tippawan Sungkapong, Richard Culleton, Kazuhide Yahata, Mayumi Tachibana, Ronatrai Ruengveerayuth, Rachanee Udomsangpetch, Motomi Torii, Takafumi Tsuboi, Jetsumon Sattabongkot, Osamu Kaneko, Kesinee Chotivanich
Southeast Asian Journal of Tropical Medicine and Public Health   42(6) 1313-1321   Dec 2011   [Refereed]
Plasmodium vivax subtelomeric transmembrane protein (PvSTP) is a homolog of P. falciparum SURFIN 42, a protein exposed on the parasite-infected erythrocyte (iE) surface, and is thus considered to be exposed on P. vivax-iE. Because antibodies targe...
Thangavelu U. Arumugam, Satoru Takeo, Tsutomu Yamasaki, Amporn Thonkukiatkul, Kazutoyo Miura, Hitoshi Otsuki, Hong Zhou, Carole A. Long, Jetsumon Sattabongkot, Jetsumon Sattabongkot, Jennifer Thompson, Danny W. Wilson, James G. Beeson, Julie Healer, Brendan S. Crabb, Alan F. Cowman, Motomi Torii, Motomi Torii, Takafumi Tsuboi, Takafumi Tsuboi, Takafumi Tsuboi
Infection and Immunity   79(11) 4523-4532   Nov 2011   [Refereed]
One of the solutions for reducing the global mortality and morbidity due to malaria is multivalent vaccines comprising antigens of several life cycle stages of the malarial parasite. Hence, there is a need for supplementing the current set of mala...
Takeshi Miyata, Tetsuya Harakuni, Takafumi Tsuboi, Takafumi Tsuboi, Jetsumon Sattabongkot, Jetsumon Sattabongkot, Ayumu Ikehara, Mayumi Tachibana, Motomi Torii, Motomi Torii, Goro Matsuzaki, Goro Matsuzaki, Takeshi Arakawa, Takeshi Arakawa
Infection and Immunity   79(10) 4260-4275   Oct 2011   [Refereed]
The creation of subunit vaccines to prevent malaria infection has been hampered by the intrinsically weak immunogenicity of the recombinant antigens. We have developed a novel strategy to increase immune responses by creating genetic fusion protei...
Jean Semé Fils Alexandre, Jean Semé Fils Alexandre, Kazuhide Yahata, Satoru Kawai, Motomi Torii, Osamu Kaneko
Parasitology International   60(3) 313-320   Sep 2011   [Refereed]
SURFIN 4.2 is a parasite-infected red blood cell (iRBC) surface associated protein of Plasmodium falciparum. To analyze the region responsible for the intracellular trafficking of SURFIN 4.2 to the iRBC and Maurer's clefts, a panel of transgenic p...
Tachibana M, Wu Y, Iriko H, Muratova O, MacDonald NJ, Sattabongkot J, Takeo S, Otsuki H, Torii M, Tsuboi T
Clin Vaccine Immunol   18(8) 1343-1350   2011   [Refereed]
Doi M, Tanabe K, Tachibana S, Hamai M, Tachibana M, Mita T, Yagi M, Zeyrek FY, Ferreira MU, Ohmae H, Kaneko A, Randrianarivelojosia M, Sattabangkot J, Cao YM, Horii T, Torii M, Tsuboi T
Vaccine   29 4308-4315   2011   [Refereed]
Ito D, Han ET, Takeo S, Thongkukiatkul A, Otsuki H, Torii M, Tsuboi T
Parasitology International   60(2) 132-138   2011   [Refereed]
Miyata T, Harakuni T, Sugawa H, Sattabongkot J, Kato A, Tachibana M, Torii M, Tsuboi T, Arakawa T
Vaccine   29(15) 2720-2726   2011   [Refereed]
Miyata T, Harakuni T, Tsuboi T, Sattabongkot J, Kohama H, Tachibana M, Matsuzaki G, Torii M, Arakawa T
Infection and Immunity   78(9) 3773-3782   Sep 2010   [Refereed]
Tsuboi T, Takeo S, Sawasaki T, Torii M, Endo Y.
Methods in molecular biology   607 73-83   2010   [Refereed]
Acta Tropica   114(3) 171-176   2010   [Refereed]
Arakawa T, Tachibana M, Miyata T, Harakuni T, Kohama H, Matsumoto Y, Tsuji N, Hisaeda H, Stowers A, Torii M, Tsuboi T
Infection and Immunity   77(12) 5496-5500   Dec 2009   [Refereed]
Tetsutani K, Ishiwata K, Ishida H, Tu L, Torii M, Hamano S, Himeno K, Hisaeda H
European Journal Immunology   39(10) 2822-2830   2009   [Refereed]
Takeo S, Arumugam TU, Torii M, Tsuboi T
Expert Opinion on Drug Discovery   4(11) 1191-1199   2009   [Refereed]
The Proceedings of the National Academy of Sciences USA (PNAS)   106(17) 7167-7172   2009   [Refereed]
IRIKO Hideyuki, IRIKO Hideyuki, IRIKO Hideyuki, JIN Ling, JIN Ling, KANEKO Osamu, KANEKO Osamu, TAKEO Satoru, HAN Eun−taek, HAN Eun−taek, TACHIBANA Mayumi, OTSUKI Hitoshi, TORII Motomi, TSUBOI Takafumi, TSUBOI Takafumi
Parasitology International   58(2) 196-199   2009   [Refereed]
CAO Jun, CAO Jun, KANEKO Osamu, KANEKO Osamu, THONGKUKIATKUL Amporn, TACHIBANA Mayumi, OTSUKI Hitoshi, GAO Qi, TSUBOI Takafumi, TSUBOI Takafumi, TORII Motomi
Parasitology International   58(1) 29-35   2009   [Refereed]
TSUBOI Takafumi, TAKEO Satoru, IRIKO Hideyuki, JIN Ling, TSUCHIMOCHI Masateru, MATSUDA Shusaku, HAN Eun‐Taek, OTSUKI Hitoshi, KANEKO Osamu, SATTABONGKOT Jetsumon, UDOMSANGPETCH Rachanee, SAWASAKI Tatsuya, TORII Motomi, ENDO Yaeta
Infection and immunity   76(4) 1702-1708   Apr 2008   [Refereed]
Short Report: Concurrent infection with Heligmosomoides polygyrus modulates murine host response against Plasmodium berghei ANKA infection
Tetsutani K, Ishiwata K, Torii M, Hamano S, Hisaeda H, Himeno K
American Journal of Tropical Medicine Hygiene   79(6) 819-822   2008   [Refereed]
Malaria parasites require TLR9 signaling for immune evasion by activating regulatory T cells.
Aramaki A, Shen J, Ishii K, Coban C, Akira S, Takeda K, Yasutomo K, Torii M, Himeno K
Journal of Immunology   180(4) 2496-2503   2008   [Refereed]
Yano K, Otsuki H, Arai M, Komaki-Yasuda K, Tsuboi T, Torii M, Kano S, Kawazu S-I
Molecular and Biochemical Parasitology   159(2) 142-145   2008   [Refereed]
Iriko H, Kaneko O, Otsuki H, Tsuboi T, Su XZ, Tanabe K, Torii M
Molecular and Biochemical Parasitology   158(1) 11-21   2008   [Refereed]
Journal of Bacteriology   189(22) 8241-8249   2007   [Refereed]
Kobayashi F, Waki S, Niikura M, Tachibana M, Tsuboi T, Torii M, Kamiya S
Experimental Parasitology   116(4) 450-457   2007   [Refereed]
Tetsutani K, To H, Torii M, Hisaeda H, Himeno K
Parasitology   134(7) 923-930   2007   [Refereed]
Yano K, Komaki-Yasuda K, Tsuboi T, Torii M, Kano S, Kawazu S
Molecular and Biochemical Parasitology   148(1) 44-51   2006   [Refereed]
Palacpac NMQ, Leung BWY, Arisue N, Sattabongkot J, Tanabe K, Tsuboi T, Torii M, Udomsangpetch R, Horii T
Molecular and Biochemical Parasitology   150(2) 353-358   2006   [Refereed]
KANEKO Osamu, TEMPLETON Thomas J., IRIKO Hideyuki, IRIKO Hideyuki, TACHIBANA Mayumi, OTSUKI Hitoshi, TAKEO Satoru, SATTABONGKOT Jetsumon, TORII Motomi, TSUBOI Takafumi, TSUBOI Takafumi
Parasitology International   55(3) 227-231   2006   [Refereed]
Arakawa T, Komesu Ai, Otsuki H, Sattabongkot J, Udomsangpetch R, Matsumoto Y, Tsuji N, Wu Y, Torii M, Tsuboi T
Infection and Immunity   73(11) 7375-7380   Nov 2005   [Refereed]
Kaneko O, Yim-Lim BYS, Iriko H, Ling IT, Otsuki H, Grainger M, Tsuboi T, Adams JH, Mattei D, Holder AA, Torii M.
Molecular and Biochemical Parasitology   143(1) 20-28   2005   [Refereed]
Rungruang T, Kaneko O, Murakami Y, Tsuboi T, Hamamoto H, Akimitsu N, Sekimizu K, Kinoshita T, Torii M
Molecular and Biochemical Parasitology   140(1) 13-21   2005   [Refereed]
Preiser P, Renia L, Singh N, Balu B, Jarra W, Voza T, Kaneko O, Blair P, Torii M, Landau I, Adams JH
Infection and Immunity   72(6) 3604-3608   Jun 2004   [Refereed]
Journal of Cell Science   117(8) 1469-1480   Apr 2004   [Refereed]
Akimitsu N, Kim HS, Hamamoto H, Kamura K, Fukuma N, Arimitsu N, Ono K, Wataya Y, Torii M, Sekimizu K
Parasitology Research   93(6) 499-503   2004   [Refereed]
Kongkasuriyachai D, Bartels-Andrews L, Stowers A, Collins WE, Sullivan J, Sattabongkot J, Torii M, Tsuboi T, Kumar N.
Vaccine   22(23-24) 3205-3213   2004   [Refereed]
Molecular Microbiology   52(1) 107-118   2004   [Refereed]
Parasitology International   53(3) 211-216   2004   [Refereed]
Katakura K, Fujise H, Takeda K, Kaneko O, Torii M, Suzuki M, Chang KP, Hashiguchi Y.
FEBS Letter   561(1-3) 207-212   2004   [Refereed]
Unique properties of respiratory chain in Plasmodium falciparum mitochondria.
Mi-Ichi F, Takeo S, Takashima E, Kobayashi T, Kim HS, Wataya Y, Matsuda A, Torii M, Tsuboi T, Kita K
Adv Exp Med Biol   531 177-133   2003   [Refereed]
Blocking of transmission to mosquitoes by antibody to Plasmodium vivax malaria vaccine candidates Pvs25 and Pvs 28 despite antigenetic polymorphism in field isolates.
Sattabongkot J, Tsuboi T, Hisaeda H, Tachibana M, Suwanabun N, Rungruang T, Cao YM, Stowers AW, Sirichaisinthop J, Coleman RE, Torii M.
American Journal of Tropical Medicine and Hygiene   69(5) 536-541   2003   [Refereed]
Kawazu S, Nozaki T, Tsuboi T, Nakano Y, Komaki-Yasuda K, Ikenoue N, Torii M, Kano S.
International Journal for Parasitology   33(13) 1455-1461   2003   [Refereed]
Tsuboi T, Kaneko O, Eitoku C, Suwanabun N, Sattabongkot J, Vinetz JM, Torii M.
Molecular and Biochemical Parasitology   130(1) 51-54   2003   [Refereed]
Tsuboi T, Tachibana M, Kaneko O, Torii M
Parasitology International   52(1) 1-11   2003   [Refereed]
Ling IT, Kaneko O, Narum DL, Tsuboi T, Howell S, Taylor HM, Scott- Finnigan TJ, Torii M, Holder AA
Molecular and Biochemical Parasitology   127(1) 47-57   2003   [Refereed]
Arakawa T, Tsuboi T, Kishimoto A, Sattabongkot J, Suwanabun N, Rungruang T, Matsumoto Y, Tsuji N, Hisaeda H, Stowers A, Shimabukuro I, Sato Y, Torii M.
Vaccine   21(23) 3143-3148   2003   [Refereed]
Kaneko O, Mu J, Tsuboi T, Su X, Torii M.
Molecular and Biochemical Parasitology   121(2) 275-278   2002   [Refereed]
Tachibana M, Tsuboi T, Kaneko O, Khuntirat B, Torii M.
Molecular and Biochemical Parasitology   122(2) 223-226   2002   [Refereed]
Shirano M, Tsuboi T, Kaneko O, Tachibana M, Adams JH, Torii M
Molecular and Biochemical Parasitology   112(2) 297-299   2001   [Refereed]
Tachibana M, Tsuboi T, Templeton TJ, Kaneko O, Torii M
Molecular and Biochemical Parasitology   113(2) 341-344   2001   [Refereed]
Yuda M, Yano K, Tsuboi T, Torii M, Chinzei Y
Molecular and Biochemical Parasitology   116(1) 65-72   2001   [Refereed]
Development of a method for the in vitro production of Plasmodium vivax ookinetes.
Suwanabun N, Sattabongkot J, Tsuboi T, Torii M, Maneechai N, Rachapaew N, Yim-amnuaychok N, Punkitchar V, Coleman RE.
Journal of Parasitology   87(4) 928-930   2001   [Refereed]
Kaneko O, Tsuboi T, Ling IT, Howell S, Shirano M, Tachibana M, Cao YM, Holder AA, Torii M.
Molecular and Biochemical Parasitology   118(2) 223-231   2001   [Refereed]
Hisaeda H, Stowers AW, Tsuboi T, Collins WE, Sattabongkot J, Suwanabun N, Torii M, Kaslow DC.
Infection and Immunity   68(12) 6618-6623   Dec 2000   [Refereed]
Langer RC, Hayward RE, Tsuboi T, Tachibana M, Torii M, Vinetz JM
Infection and Immunity   68(11) 6461-6465   Nov 2000   [Refereed]
Zhang M, Hisaeda H, Tsuboi T, Torii M, Sakai T, Nakao Y, Ishikawa H, Maekawa Y, Good RA, Himeno K
Experimental Parasitology   93(1) 61-65   1999   [Refereed]
Parasitology International   47(2) 157-166   1998   [Refereed]
Parasitology International   47(3) 225-232   1998   [Refereed]
Sequence polymorphism in two novel Plasmodium vivax ookinete surface proteins, Pvs25 and Pvs28, that are malaria transmission-blocking vaccine candidates.
Tsuboi T., Kaslow DC, Gozar MM, Tachibana M., Cao YM, Torii M.
Molecular Medicine   4(12) 772-782   1998   [Refereed]
Two antigens on zygotes and ookinetes of Plasmodium yoelii and Plasmodium berghei that are distinct targets of transmission-blocking immunity.
Tsuboi T, Cao YM, Hitsumoto Y, Yanagi T, Kanbara H, Torii M
Infection and Immunity   65(6) 2260-2264   Jun 1997   [Refereed]
Molecular and Biochemical Parasitology   85(1) 131-134   1997   [Refereed]
Aikawa M, Kawazu S, Kamio T, Matsumoto Y, Torii M, Ito Y, Tandler B, Nakao Y, Takeuchi T, Shiraishi S, Kanamura K
Parasitology International   46(4) 241-246   1997   [Refereed]
Aikawa M, Kanamura K, Shiraishi S, Matsumoto Y, Arwati H, Torii M, Ito Y, Takeuchi T, Tandler B
Experimental Parasitology   84(3) 339-343   1996   [Refereed]
Murine complement reduces infectivity of Plasmodium yoelii to mosquitoes.
Tsuboi T, Cao Y-M, Torii M, Hitsumoto Y, Kanbara H
Infection and Immunity   63(9) 3702-3704   Sep 1995   [Refereed]
The fatty acids of each lipid fraction and their use in providing energy source of the plerocercoid of Spirometra erinacei.
Fukushima T, Isobe A, Hojo N, Shiwaku K, Yamane Y, Torii M
International Journal for Parasitology   25(1) 15-21   1995   [Refereed]
Adhesion of Plasmodium falciparum-infected erythrocytes to human cells and secretion of cytokines (IL-1-beta, IL-1RA, IL-6, IL-8, IL-10, TGF-beta, TNF alpha, G-CGF, GM-CSF).
Wahlgren M, Abrams JS, Fernandez V, Bejarano MT, Azuma M, Torii M, Aikawa M, Howard RJ
Scadinavian Journal of Immunology   42(6) 626-636   1995   [Refereed]
Hepatotrophic activity in mouse serum infected with plerocercoids of Spirometra erinacei.
Tsuboi T, Torii M, Oka K, Hirai K
Parasitology Research   80(8) 629-633   1994   [Refereed]
Characteristics of the growth hormone-like factor produced by plerocercoids of Spirometra erinacei.
Japanese Journal of Parasitology   42(3) 185-192   1993
The metabolism of arachidonic acid to prostaglandin E2 in plerocercoids of Spirometra erinacei.
Parasitology Research   79 634-638   1993   [Refereed]
Light and scanning electron microscopy of Diphyllobothrium pacificum expelled from a man.
Takafumi TSUBOI, Motomi TORII, Kazumitsu HIRAI
Japanese Journal of Parasitology   42(5) 422-428   1993   [Refereed]
Experimental infection of wild boars with metacercariae of Paragonimus miyazakii (Trematoda: Trogrotrematidae).
Japanease Journal of Parasitology   41 274-278   1992   [Refereed]
Expression and subcellular localization of Plasmadium falciparum aldolase.
Journal of Protozoology Research   2(1) 10-15   1992   [Refereed]
Appearance and localization of Loasmodium yoelii circumsporozoite protein during sporogony in anopheles stephensi.
Journal of Protozoology Research   2(4) 134-140   1992   [Refereed]


54(8) 1041-1046   2009

Books etc

Malaria Parasite Biology, Pathogenesis, and protection
American Society for Microbiology PressAmerican Society for Microbiology   1998   
Advances in Experimental Medicine and Biology, Vol 531, Tropical Diseases: From Molecule To Bedside
Kluwer/Springer   2003   
Methods in Molecular Biology, vol607, Cell-Free Protein Production : Methods and Protocols
Humana Press   2009   
Cell-free protein production: Methods and protocols. Methods in Molecular Biology 607
Humana Press, a part of Springer Science+Business Media   2010   

Conference Activities & Talks

Functional analysis of a sporozoite rhoptry protein hepatocyte infection
Sirasate Bantuchai, Mamoru Nozaki, Amporn Thongkukiatkul, Natcha Lorsuwannarat, Mayumi Tachibana, Kazuhiro Matsuoka, Takafumi Tsuboi, Motomi Torii, Tomoko Ishino
66th Annual meeting of American Society of Tropical Medicine & Hygene   2017   
PyGM75, a protein in osmiophilic bodies, is dispensable for egress of male gametocytes but important for exflagellation of microgametes
Mayumi Tachibana, Motomi Torii, Takafumi Tsuboi, Tomoko Ishino
66th Annual meeting of American Society of Tropical Medicine & Hygene   2017   
C-terminus region of male gamete surface protein, PyGM75 induce malaria transmission-blocking antibody
Mayumi Tachibana, Motomi Torii, Moe Sudo, Takafumi Tsuboi, Tomoko Ishino
Molecular approaches to Malaria 2016   2016   
Rhoptry proteins have important roles during sporozoite invasion of mosquito salivary glands or mammalian hepatocytes
Tomoko Ishino, Yuka Sugino, Mamoru Nozaki, Eri Murata, Naohito Tokunaga, Mayumi Tachibana, Takafumi Tsuboi, Motomi Torii
Molecular approaches to Malaria 2016   2016   
Functional analyses of sporozoite rhoptry proteins of Plasmodium berghei during target cell invasion
Tomoko Ishino
2nd International Symposium "matryoshika-type Evolution"   2015   

Research Grants & Projects

Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2009 - 2011    Investigator(s): Motomi TORII
The aim of the malaria transmission-blocking vaccine(TBV) is to block the development of malaria parasites in the mosquito and prevent the following infection to the host. We focused on the Pvs230 as a candidate molecule, and produced recombinant ...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2009 - 2011    Investigator(s): Motomi TORII
Characterization of P36p, the sporozoite secreted proteins involved in hepatocyte infection, was performed using monoclonal antibody. It was revealed that P36p starts expression after sporozoites released into hemolymph and stored in microneme, th...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2007 - 2009    Investigator(s): Motomi TORII
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2006 - 2008    Investigator(s): Motomi TORII
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(特定領域研究)
Project Year: 2004 - 2005    Investigator(s): Motomi TORII
Parasitophorous vacuole formation is a critical step for the successful invasion of host erythrocytes by malaria parasite. Rhoptry proteins are believed to have essential roles in vacuole formation, although their biological roles are poorly under...